Results 71 to 80 of about 5,445,983 (296)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Two-process Model and Residual Abundance Analysis of the Milky Way Massive Satellites

open access: yesThe Astrophysical Journal
The “two-process model” is a promising technique for interpreting stellar chemical abundance data from large-scale surveys (e.g., the Sloan Digital Sky Survey IV/V and the Galactic Archeology with HERMES survey), enabling more quantitative empirical ...
Sten Hasselquist   +6 more
doaj   +1 more source

Differential abundances of open clusters and their tidal tails : Chemical tagging and chemical homogeneity

open access: yes, 2020
Context: Well studied open clusters (OCs) of the solar neighborhood are frequently used as reference objects to test galactic and stellar theories. For that purpose, their chemical composition needs to be known with a high level of confidence. It is also
Heiter, Ulrike   +20 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Metallicities from High-resolution TRES Spectra with uberMS: Performance Benchmarks and Literature Comparison

open access: yesThe Astrophysical Journal Supplement Series
As the field of exoplanetary astronomy has matured, demand has grown for precise stellar abundances to probe subtle correlations between stellar compositions and planetary demographics.
Emily K. Pass   +9 more
doaj   +1 more source

The Sunburst Arc with JWST. III. An Abundance of Direct Chemical Abundances

open access: yesThe Astrophysical Journal
Abstract We measure the gas-phase abundances of the elements He, N, O, Ne, S, Ar, and Fe in an individual H ii region known to be leaking Lyman-continuum photons in the Sunburst Arc, a highly magnified galaxy at redshift z = 2.37. We detect the temperature-sensitive auroral lines [S ii] λλ4070, 4076, [O iii] λ4363, [S ...
Brian Welch   +13 more
openaire   +3 more sources

Chemical abundances across the first kpc of the LMC

open access: yes, 2019
The chemical evolution of the Large Magellanic Cloud (LMC) yields information on many different aspects of low-mass disc galaxy evolution, and the evolution of an interacting system.
Van der Swaelmen, Mathieu (8343477)   +1 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Hot Stars in Stellar Populations of Galaxies

open access: yesGalaxies
Star-forming galaxies are hosts of dominant populations of recently formed, hot, massive stars, which give rise to conspicuous stellar spectral features and provide the ionizing fluxes. Strong outflows of these stars shape their properties.
Claus Leitherer
doaj   +1 more source

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