Results 81 to 90 of about 5,855,365 (255)
Aeos Is Mixing It Up: The (In)homogeneity of Metal Mixing Following Population III Star Formation
The Astrophysical JournalStellar surface abundances are records of the state of the gas from which stars formed and thus trace how individual elements have mixed into the surrounding medium following their ejection from stars.
Jennifer Mead +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Astrophysical JournalMetal-poor stars are crucially important for understanding the early Galaxy, first stars, and the Universe. In this series of papers, we present a homogeneous non–local thermodynamic equilibrium (NLTE) abundance analysis of 12 elements for 103 very metal-
Hong-Liang Yan +14 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A Catalogue of Planetary Nebulae Chemical Abundances in the Galactic Bulge [PDF]
In this, the third of a series of papers, we present well determined chemical abundances for 124 Planetary nebulae (PNe) in the Galactic bulge from deep, long-slit FORS2 spectra from the 8.2 m ESO Very Large telescope (VLT). Prior to this work there were
Parker, Quentin A. +3 more
core +1 more source
Oxygen abundances and the chemical evolution of spiral galaxies
, 1983 This is an electronic version of an article published in Memorie della Società Astronomica Italiana. Tosi, M. and A. I. Díaz. Oxygen abundances and the chemical evolution of spiral galaxies.
Tosi, M. +1 more
core +1 more source
The High-Redshift Gas-Phase Mass–Metallicity Relation in FIRE-2
The Astrophysical Journal LettersThe unprecedented infrared spectroscopic capabilities of JWST have provided high-quality interstellar medium metallicity measurements and enabled characterization of the gas-phase mass–metallicity relation (MZR) for galaxies at z ≳ 5 for the first time ...
Andrew Marszewski +4 more
doaj +1 more source
Astronomy & AstrophysicsContext. In the current era, in which an unprecedented wealth of data are available for the study of the Milky Way, Gaia benchmark stars (GBSs) have become an established reference and calibration sample. Studies of stellar structure and evolution and of
Vitali S. +12 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Chemical abundances from planetary nebulae in local spiral galaxies
, 2015 While the chemical abundances observed in bright planetary nebulae in local spiral galaxies are less varied than their counterparts in dwarfs, they provide new insight.
Marshall L. McCall, Michael G. Richer
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