Results 81 to 90 of about 84,685 (303)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The RRc Stars: Chemical Abundances and Envelope Kinematics [PDF]

open access: yesThe Astrophysical Journal, 2017
Abstract We analyzed series of spectra obtained for 12 stable RRc stars observed with the echelle spectrograph of the du Pont telescope at Las Campanas Observatory and we analyzed the spectra of RRc Blazhko stars discussed by Govea et al.
Sneden, Christopher   +3 more
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Hot Stars in Stellar Populations of Galaxies

open access: yesGalaxies
Star-forming galaxies are hosts of dominant populations of recently formed, hot, massive stars, which give rise to conspicuous stellar spectral features and provide the ionizing fluxes. Strong outflows of these stars shape their properties.
Claus Leitherer
doaj   +1 more source

Carbon-driven Chemical Interactions between Alumina and Iron: A possible reaction pathway in Earth's interior

open access: yes, 2008
Seismological and geochemical observations have revealed a complex structure for the earth's core-mantle boundary (CMB) region, with lateral and chemical heterogeneities.
Rita Khanna   +2 more
core  

Optimal integrated abundances for chemical tagging of extragalactic globular clusters [PDF]

open access: yes, 2015
High-resolution integrated light (IL) spectroscopy provides detailed abundances of distant globular clusters whose stars cannot be resolved. Abundance comparisons with other systems (e.g.
Shetrone, Matthew   +4 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Recent Advances in Understanding R-Process Nucleosynthesis in Metal-Poor Stars and Stellar Systems

open access: yesUniverse
The rapid neutron-capture process (r-process) is responsible for the creation of roughly half of the elements heavier than iron, including precious metals like silver, gold, and platinum, as well as radioactive elements such as thorium and uranium ...
Avrajit Bandyopadhyay, Timothy C. Beers
doaj   +1 more source

The Open Cluster Chemical Abundances from Spanish Observatories survey (OCCASO) [PDF]

open access: yes, 2015
We present the motivation, design and current status of the Open Cluster Chemical Abundances from Spanish Observatories survey (OCCASO). Using the high resolution spectroscopic facilities available at Spanish observatories, OCCASO will derive chemical ...
Jordi, C.   +12 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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