Results 111 to 120 of about 596,259 (322)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Metal-poor Star-forming Clumps in Cosmic Noon Galaxies: Evidence for Gas Inflow and Chemical Dilution Using JWST NIRISS

The Astrophysical Journal
The formation and evolution of galaxies are intricately linked to the baryon cycle, which fuels star formation while shaping chemical abundances within galaxies.
Vicente Estrada-Carpenter, Marcin Sawicki, Roberto Abraham, Yoshihisa Asada, Maruša Bradač, Gabe Brammer, Guillaume Desprez, Kartheik G. Iyer, Nicholas S. Martis, Adam Muzzin, Gaël Noirot, Gregor Rihtaršič, Ghassan T. E. Sarrouh, Chris J. Willott, Jeremy Favaro, Vladan Markov, Rosa M. Mérida, Katherine Myers, Visal Sok   +18 more
doaj   +1 more source

Chemical enrichment and star formation in the Milky Way disk III. Chemodynamical constraints

, 2004
In this paper, we investigate some chemokinematical properties of the Milky Way disk, by using a sample composed by 424 late-type dwarfs. We show that the velocity dispersion of a stellar group correlates with the age of this group, according to a law ...
Asiain, Avila-Reese, Barbier-Brossat, Bassino, Berczik, Berczik, Bizyaev, Burkert, Byl, Byl, C. Flynn, Carlberg, Carlberg, Carlberg, Chiba, Cubarsí, Dehnen, Dehnen, Dehnen, Dempster, Duflot, Duflot, Edvardsson, Eggen, Elmegreen, Feast, Fehrenbach, Fehrenbach, Flynn, Font, Fridman, Friedli, Fujimoto, Fux, G. Hensler, Gerssen, Gerssen, Gilmore, Gratton, Gómez, H. J. Rocha-Pinto, Hartmann, Hilton, House, Hänninen, Ibata, J. Hänninen, J. Scalo, Jahreiß, Jeffries, Jenkins, Jenkins, Johnson, Kato, Knude, Kokubo, Kroupa, Köppen, Köppen, Lacey, Lacey, Larson, Larson, Mac Low, Maciel, Majewski, Mayor, Mayor, Mayor, Meusinger, Moreno, Mühlbauer, Nemec, Newberg, Nordström, Nordström, Núñez, Oblak, Ojha, Ostriker, Raiteri, Ratnatunga, Robin, Rocha-Pinto, Rocha-Pinto, Rocha-Pinto, Rocha-Pinto, Rocha-Pinto, Roman, Roman, Samland, Scalo, Sellwood, Semenzato, Shapiro, Skuljan, Soderblom, Sotnikova, Spitzer, Spitzer, Steinmetz, Steinmetz, Taylor, Tinsley, Velázquez, Villumsen, W. J. Maciel, Wielen, Wielen, Yanny, Yasutomi, Yasutomi, Yuan   +112 more
core   +1 more source

Chemical enrichment in LINERs from MaNGA

Astronomy & Astrophysics
Context. The chemical enrichment in low-ionization nuclear emission-line regions (LINERs) is still an issue with spatial resolution spectroscopic data because we lack studies and because the nature of their ionizing source is uncertain, although they are the most abundant type of active galaxies in the nearby Universe. Aims.
Borja Pérez-Díaz, Enrique Pérez-Montero, Igor A. Zinchenko, José M. Vílchez   +3 more
openaire   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Rapid Chemical Enrichment by Intermittent Star Formation in GN-z11

The Astrophysical Journal Letters
We interpret the peculiar supersolar nitrogen abundance recently reported by the James Webb Space Telescope observations for GN-z11 ( z = 10.6) using our state-of-the-art chemical evolution models.
Chiaki Kobayashi, Andrea Ferrara
doaj   +1 more source

The self-enrichment of galactic halo globular clusters : a clue to their formation ? [PDF]

, 1999
We present a model of globular cluster self-enrichment. In the protogalaxy, cold and dense clouds embedded in the hot protogalactic medium are assumed to be the progenitors of galactic halo globular clusters.
Jehin, E., Magain, P., Neuforge, C., Noels, A., Parmentier, G., Thoul, A. A.   +5 more
core   +1 more source

The most metal-poor damped Ly alpha system at z<3: constraints on early nucleosynthesis

, 2006
To constrain the conditions for very early nucleosynthesis in the Universe we compare the chemical enrichment pattern of an extremely metal-poor damped Lyman alpha (DLA) absorber with predictions from recent explosive nucleosynthesis model calculations ...
Akerman, Allende Prieto, Aoki, Bromm, C. Ledoux, Centurión, Chieffi, Christlieb, Ciardi, D'Odorico, Daigne, Fontana, Frebel, Grevesse, Heger, Henry, Israelian, Izotov, Kawata, Kobayashi, Lanfranchi, Lanzetta, Ledoux, Ledoux, Levshakov, Levshakov, Levshakov, Matteucci, McWilliam, Morton, Nakamura, Oh, Omukai, Omukai, P. Erni, P. Petitjean, P. Richter, Pettini, Prochaska, Prochaska, Péroux, Rao, Richter, Schneider, Songaila, Spite, Storrie-Lombardi, Strolger, Tumlinson, Umeda, Vladilo, Wolfe   +51 more
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source