Results 101 to 110 of about 10,989 (277)

Gancidin W, a potential low-toxicity antimalarial agent isolated from an endophytic Streptomyces SUK10

Drug Design, Development and Therapy, 2017
Noraziah Mohamad Zin,1 Mohd Shukri Baba,2 Abu Hassan Zainal-Abidin,3 Jalifah Latip,4 Noor Wini Mazlan,5 RuAngelie Edrada-Ebel6 1Programme of Biomedical Science, School of Diagnostic and Applied Health Sciences, Faculty of Health Sciences, Universiti ...
Zin NM, Baba MS, Zainal-Abidin AH, Latip J, Mazlan NW, Edrada-Ebel R   +5 more
doaj  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Synthesis and Biological Evaluation of Imidazopyridine-Isatin Hybrids as Inhibitors of Leishmania major Growth

Drug Design, Development and Therapy
Mahmoud A El Hassab,1 Wagdy M Eldehna,2 Zainab M Elsayed,3 Mostafa M Elbadawi,2 Ahmed T Negmeldin,4,5 Marwa Balaha,2,6 Sherry N Nasralla,7 Rehan Monir,8 Tamer M Ibrahim,2 Manabu Abe,9 Haytham O Tawfik,10 Adnan A Bekhit,7,11 Loah R Hemeda12 1Department of
El Hassab MA, Eldehna WM, Elsayed ZM, Elbadawi MM, Negmeldin AT, Balaha M, Nasralla SN, Monir R, Ibrahim TM, Abe M, Tawfik HO, Bekhit AA, Hemeda LR   +12 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The development of green analytical methods to monitor adulteration in honey by UV-visible spectroscopy and chemometrics models

, 2020
The development of green and environmentally friendly analytical methods for agri-food products is an essential element to be treated by green analytical chemistry.
Aimen El Orche, Omar Elhamdaoui, Mustapha Bouatia, Miloud El Karbane, Amine Cheikh, Houda Bouchafra   +5 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Prenatal bisphenol A exposure perturbs sex-dependent transcriptomic regionalization of autism-associated genes in the developing brain

Biology Direct
Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in communication, social interaction, and behavioral regulation.
Suporn Sukjamnong, Thanit Saeliw, Pawinee Panjabud, Surangrat Thongkorn, Songphon Kanlayaprasit, Pattanachat Lertpeerapan, Valerie W. Hu, Tewarit Sarachana   +7 more
doaj   +1 more source

Exploring advanced functional nanomaterial-based electrochemical sensors for the detection of mycotoxins in food matrices: A comprehensive review

Chemistry of Inorganic Materials
The detection of mycotoxins is a worldwide issue given their significant effects on both food safety and human health. The European Union (EU) has implemented various measures to address mycotoxin contamination and regulate their levels in food and feed.
Rupali P. Kalambate, Pramod K. Kalambate, Hossein Khosropour, Parichut Thummarati, Anchalee Chiabchalard, Watcharee Boonlue, Wanida Laiwattanapaisal   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Analogues of antibacterial natural products

, 2012
This thesis is concerned with the synthesis and biological evaluation of structural mimics for the natural products 16-methyloxazolomycin and lemonomycin which display potent biological activity including antibacterial and antitumour activity. Chapter 1
Heaviside, Elizabeth Anne, Heaviside, Elizabeth   +1 more
core   +1 more source