Results 21 to 30 of about 10,194 (239)

Cleistocalyx nervosum var. paniala Berry Seed Protects against TNF-α-Stimulated Neuroinflammation by Inducing HO-1 and Suppressing NF-κB Mechanism in BV-2 Microglial Cells

Molecules, 2023
Sustained inflammatory responses have been implicated in various neurodegenerative diseases (NDDs). Cleistocalyx nervosum var. paniala (CN), an indigenous berry, has been reported to exhibit several health-beneficial properties. However, investigation of
Sakawrat Janpaijit, Chanin Sillapachaiyaporn, Atsadang Theerasri, Somsri Charoenkiatkul, Monruedee Sukprasansap, Tewin Tencomnao   +5 more
doaj   +1 more source

Neuroprotective Effects of Extracts from Tiger Milk Mushroom Lignosus rhinocerus Against Glutamate-Induced Toxicity in HT22 Hippocampal Neuronal Cells and Neurodegenerative Diseases in Caenorhabditis elegans

Biology, 2021
Despite the Tiger Milk Mushroom Lignosus rhinocerus (LR) having been used as a traditional medicine, little is known about the neuroprotective effects of LR extracts.
Parinee Kittimongkolsuk, Nattaporn Pattarachotanant, Siriporn Chuchawankul, Michael Wink, Tewin Tencomnao   +4 more
doaj   +1 more source

Antioxidant and Anti-Skin Aging Potential of Selected Thai Plants: In Vitro Evaluation and In Silico Target Prediction

Plants, 2022
The skin is the largest organ that performs a variety of the body’s essential functions. Impairment of skin structure and functions during the aging process might severely impact our health and well-being. Extensive evidence suggests that reactive oxygen
Kamonwan Chaikhong, Sawarin Chumpolphant, Panthakarn Rangsinth, Chanin Sillapachaiyaporn, Siriporn Chuchawankul, Tewin Tencomnao, Anchalee Prasansuklab   +6 more
doaj   +1 more source

A computational pipeline combining machine learning and molecular simulations identifies repurposed PI3Kα inhibitors from FDA-approved drugs

Artificial Intelligence Chemistry
The computational repurposing of existing drugs has proven to be a fast-track strategy in the development of new cancer therapy. Nonetheless, integrated mechanistically grounded approaches are required for a more reliable in silico identification of new ...
Prince Danan Biniyam, Naomi Kayeri, Seth Junior Ayihi, Syed Arslan Haider, Hope Dzitorwoko, Kwabena Adu-Adjei, Michael Osei, Victoria Ohene-Adu, Portia Frimpong, Clifford Tignangnen Penajah, Silas Boakye Amissah, Nimra Mazhar, Cedric Dzidzor Kodjo Amengor   +12 more
doaj   +1 more source

Thai plants with high antioxidant levels, free radical scavenging activity, anti-tyrosinase and anti-collagenase activity

BMC Complementary and Alternative Medicine, 2017
Background Ultraviolet radiation from sunlight induces overproduction of reactive oxygen species (ROS) resulting in skin photoaging and hyperpigmentation disorders.
Moragot Chatatikun, Anchalee Chiabchalard   +1 more
doaj   +1 more source

Comparative assessment of the physicochemical properties of antacid suspensions available in the Ho Municipality of the Volta Region of Ghana

Scientific African, 2021
Antacids are over-the-counter medications that neutralize stomach acid and inhibit pepsin activity. They are used to relieve symptoms associated with some upper gastrointestinal disorders.
Hilda Amekyeh, Adelaide Mensah, Yussif Saaka, Emmanuel Orman   +3 more
doaj   +1 more source

ChatGPT Generated Content and Similarity Index in Chemistry & Allied Sciences

, 2023
The main objective of this study is to verify similarity index of ChatGPT generated content in the field of chemistry and its allied subjects. To complete this study twenty sub subjects of chemistry based on controlled vocabulary tools such as Dewey Decimal Classification (DDC) system, Sears List of Subject Headings and Library of Congress Subject ...
openaire   +1 more source

Neuroprotective Effects against Glutamate-Induced HT-22 Hippocampal Cell Damage and Caenorhabditis elegans Lifespan/Healthspan Enhancing Activity of Auricularia polytricha Mushroom Extracts

Pharmaceuticals, 2021
Oxidative stress is associated with several diseases, particularly neurodegenerative diseases, commonly found in the elderly. The attenuation of oxidative status is one of the alternatives for neuroprotection and anti-aging.
Chanin Sillapachaiyaporn, Panthakarn Rangsinth, Sunita Nilkhet, Alison T. Ung, Siriporn Chuchawankul, Tewin Tencomnao   +5 more
doaj   +1 more source

Association of Drug-Metabolizing Enzyme and Transporter Gene Polymorphisms and Lipid-Lowering Response to Statins in Thai Patients with Dyslipidemia

Pharmacogenomics and Personalized Medicine, 2022
Natchaya Vanwong,1,2 Sayanit Tipnoppanon,1 Chalitpon Na Nakorn,3 Pornpen Srisawasdi,4 Punyanuch Rodcharoen,4 Sadeep Medhasi,5 Pajaree Chariyavilaskul,2,6,7 Sarawut Siwamogsatham,2,8,9 Yongkasem Vorasettakarnkij,2,9 Chonlaphat Sukasem10– 12 1Department of
Vanwong N, Tipnoppanon S, Na Nakorn C, Srisawasdi P, Rodcharoen P, Medhasi S, Chariyavilaskul P, Siwamogsatham S, Vorasettakarnkij Y, Sukasem C   +9 more
doaj  

The need for a functional pharmaceutical industry in Sierra Leone: lessons from the COVID-19 pandemic

Journal of Pharmaceutical Policy and Practice, 2022
With an estimated population of 8.3 million, Sierra Leone has no existing pharmaceutical manufacturing company at present. The recent COVID-19 pandemic brought to the limelight the fragility and weakness of the Sierra Leonean pharmaceutical industry as ...
Eugene Conteh, Melody Okereke, Foday Umaro Turay, Alhaji Sununu Bah, Abdulwasiu Muhsinah   +4 more
doaj   +1 more source