Results 131 to 140 of about 478,848 (342)
Arthritis Care &Research, EarlyView.Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder +5 more
wiley +1 more source
The Multitasking Potential of Alarmins and Atypical Chemokines
Frontiers in Medicine, 2019 When the human genome was sequenced, it came as a surprise that it contains “only” 21,306 protein-coding genes. However, complexity and diversity are multiplied by alternative splicing, non-protein-coding transcripts, or post-translational modifications (
Aphrodite Kapurniotu +4 more
doaj +1 more source
Chemokines, chemokine receptors and the gastrointestinal system
World Journal of Gastroenterology, 2013 The biological properties of tumor cells are known to be regulated by a multitude of cytokines and growth factors, which include epidermal growth factor receptor agonists and members of the transforming growth factor β family. Furthermore, the recent explosion of research in the field of chemokine function as mediators of tumor progression has led to ...
Hiroshi Miyazaki +2 more
openaire +3 more sources
Arthritis Care &Research, EarlyView.Objective Cognitive impairment (CI) is common in patients with systemic lupus erythematosus (SLE). Despite its prevalence, the immune mechanisms are not well understood. We previously reported elevated serum levels of S100A8/A9 and matrix metalloproteinase 9 (MMP‐9) in patients with SLE and CI.
Carolina Muñoz‐Grajales +18 more
wiley +1 more source
Immunoglobulin E plus antigen challenge induces a novel intercrine/chemokine in mouse mast cells. [PDF]
, 1992 Peter Kulmburg +4 more
openalex +1 more source
Arthritis Care &Research, Accepted Article.Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla +13 more
wiley +1 more source
Regulation of Chemokine Production by the Oxidative Metabolism of L-Arginine in a Human Mixed Lymphocyte Reaction [PDF]
, 1994 Jonathan B. Orens +6 more
openalex +1 more source
Advanced Biology, EarlyView.The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li +10 more
wiley +1 more source
Effects of Clostridium difficile on the human immune response [PDF]
, 2013 Clostridium difficile is a bacterium that is rapidly becoming a large issue in the medical community due to its tendency to infect hospital patients and its resistance to antibiotics.
McGovern, Mike
core +1 more source
Production of the RANTES chemokine in delayed-type hypersensitivity reactions: involvement of macrophages and endothelial cells. [PDF]
, 1994 Odile Devergne +9 more
openalex +1 more source