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CXCR3 signaling promotes Delta One T cell recruitment and antitumor efficacy in colorectal cancer. [PDF]

open access: yesJ Immunother Cancer
Carreira M   +8 more
europepmc   +1 more source
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Chemokines

Developmental & Comparative Immunology, 2004
Chemokines are small proteins that control cellular migration. An extensive family of these molecules has been described in mammals containing nearly 50 members. Within this family are four groups, each defined by the different spacing of two N-terminal cysteines, which form disulphide bonds with two other cysteine residues to create the tertiary ...
Kerry J, Laing, Christopher J, Secombes
openaire   +2 more sources

Chemokines, chemokine receptors and hematopoiesis

Immunological Reviews, 2000
Hematopoiesis during steady state conditions is regulated and finely tuned by a network of cytokines and their effects on hematopoietic stem and progenitor cells and on accessory cells that influence the stem and progenitor cells. Amongst the numerous cytokines implicated in this regulation are members of the CC, CXC and C family of chemokines.
B S, Youn, C, Mantel, H E, Broxmeyer
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Chemokines

2009
Tumor growth is restricted to approximately 2 microm diameters by simple dissociation of nutrients and oxygen. Hence, tumors require the formation of new blood vessels for further growth progression. This process is referred to as tumor neo-angiogenesis. The process of tumor neo-angiogenesis is directed by complex bidirectional interactions between the
Andreas, Hippe   +2 more
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Chemokines, Chemokine Receptors and Allergy

International Archives of Allergy and Immunology, 2001
Chemokines are a group of cytokines that are responsible for the influx of blood cells, including T and B lymphocytes, monocytes, neutrophils, eosinophils and basophils, in allergic and other inflammatory conditions. They function as G protein-coupled chemotactic factors which also activate the cells with which they interact.
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Chemokines and Chemokine Receptors in Scleroderma

International Archives of Allergy and Immunology, 2006
Scleroderma is a connective tissue disease with unknown etiology characterized by excessive deposition of extracellular matrix in the skin. Cellular infiltrates of certain immune cells and proinflammatory mediators are suggested to play a crucial role in cutaneous fibrosis, forming complicated networks between fibroblasts and immune cells via cell-cell
openaire   +2 more sources

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