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Chemokines and Chemokine Receptors Encoded by Cytomegaloviruses
2008CMVs carry several genes that are homologous to genes of the host organism. These include genes homologous to those encoding chemokines (CKs) and G protein-coupled receptors (GPCRs). It is generally assumed that these CMV genes were hijacked from the host genome during the long co-evolution of virus and host.
Beisser, PS +3 more
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Chemokine/Chemokine Receptor Nomenclature
Journal of Interferon & Cytokine Research, 2002Kevin, Bacon +18 more
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Introduction to Chemokines and Chemokine Antagonists
2004Chemokines are small, soluble proteins with four conserved cysteines (Baggiolini et al. 1994, 1997). They consist of about 70–130 amino acids yielding molecular weights in the range of 7–15 kDa, and are synthesized with a leader sequence of 20–25 amino acids, which is cleaved off before release.
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2016
Chemokines are a large family of secreted cytokines whose main function is to mediate leukocyte directional migration. Most cancers contain chemokines and express chemokine receptors as a consequence of the activity of deregulated transcription factors or tumor-suppressor genes.
Caronni N. +5 more
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Chemokines are a large family of secreted cytokines whose main function is to mediate leukocyte directional migration. Most cancers contain chemokines and express chemokine receptors as a consequence of the activity of deregulated transcription factors or tumor-suppressor genes.
Caronni N. +5 more
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International Journal of Cancer, 2004
AbstractThe chemokines and their receptors are a superfamily of small secreted molecules that control the migration of many cell types in the body. Several years ago it became clear that some chemokines and receptors regulate the migration of certain cells in the lymphoid system, and this raised the possibility that chemokines could also control the ...
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AbstractThe chemokines and their receptors are a superfamily of small secreted molecules that control the migration of many cell types in the body. Several years ago it became clear that some chemokines and receptors regulate the migration of certain cells in the lymphoid system, and this raised the possibility that chemokines could also control the ...
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Chemokine and Chemokine Receptor Analysis
2016This chapter describes the methodological approaches to studying the role of chemokines and chemokine receptors in the physiology of immune and inflammatory responses. Chemokines share the common function of attracting leukocytes to sites of an inflammatory or immune response.
Sabina A. Islam +2 more
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