Results 221 to 230 of about 87,127 (319)

Sequential ultrasound‐driven dynamic control of macrophage polarization combined with hydrogel for mechano‐chemical synergistic tissue repair

Interdisciplinary Medicine, EarlyView.
This study presents an innovative therapeutic strategy that integrates sequential ultrasound therapy with an injectable oxidized dextran‐metformin (ODE‐Met) hydrogel to dynamically regulate macrophage polarization and promote angiogenesis for inflamed tissue repair.
Fulong Man, Kun Wang, Zichen Yang, Lulu An, Caoyi You, Rongjie Li, Yanni Cai, Yang Li, Li Chen, Yiqiong Liu, Yan Li, Haiqing Dong, Yongyong Li   +12 more
wiley   +1 more source

Strategies for inhibition of chemokine (CCL2) mediated monocyte migration

International Journal of Surgery, 2013
Saleki, Mahsa, Dark, John, Ali, Simi
openaire   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender, Rosalind Hughes, Brian Kirby   +2 more
wiley   +1 more source

In Vitro Evaluation of the Inhibitory Effects of Linarin on Histamine‐Induced Expression of Proinflammatory Cytokines, Mucin 5AC, and Aquaporin 5 in Human Nasal and Bronchial Epithelial Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Allergic rhinitis and asthma are two prevalent chronic allergic conditions in children. Linarin, a glycosylated flavonoid derived from various plants, exhibits a wide range of biological activities. This study aimed to investigate the therapeutic potential of linarin against allergic rhinitis and asthma.
Xin‐Jing Mi, Jie Wang, Jian‐Qiang Qi
wiley   +1 more source

Amphiregulin (AREG); monocyte chemoattractant protein-1 (MCP-1; CCL2); chemokine CC motif ligand 7 (CCL7; MCP3; SCYA6); CC chemokine receptor 1 (CCR1; CD191) [PDF]

, 2013

openalex   +1 more source

Systematic Deciphering of ATBC Nephrotoxicity Mechanisms via Machine Learning and Single‐Cell Analysis

Medicine Bulletin, EarlyView.
This study elucidates the nephrotoxic mechanism of acetyl tributyl citrate (ATBC) by integrating network toxicology, machine learning, and single‑cell multi‑omics analysis to systematically decipher the molecular mechanisms and cell‑type‑specific regulatory networks underlying ATBC‑induced kidney injury. First, a protein‑protein interaction network was
Yimao Wu, Yalun Liang, Jintao Liang, Wenlong Sun, Qian Zhang, Meng‐Yao Li   +5 more
wiley   +1 more source

β (CCL2) and α (CXCL10) chemokine modulations by cytokines and peroxisome proliferator-activated receptor-α agonists in Graves' ophthalmopathy [PDF]

, 2012
Alessandro Antonelli, Silvia Martina Ferrari, Silvia Frascerra, Ilaria Ruffilli, Cinzia Pupilli, Giampaolo Bernini, Stefano Sellari‐Franceschini, Stefania Gelmini, Ele Ferrannini, Poupak Fallahi   +9 more
openalex   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Data from The Chemokine (CCL2–CCR2) Signaling Axis Mediates Perineural Invasion

, 2023
Shizhi He, Shuangba He, Chun‐Hao Chen, Sylvie Deborde, Richard L. Bakst, Natalya Chernichenko, William F. McNamara, Sei Young Lee, Fernando Barajas, Zhenkun Yu, Hikmat Al‐Ahmadie, Richard Wong   +11 more
openalex   +1 more source

Alveolar Fibroblasts Respond to Pseudomonas Aeruginosa Infection With Cytokine Secretion: Role in Acute Lung Inflammation

Med Research, EarlyView.
ABSTRACT Alveolar fibroblasts play a key role in regulation of lung inflammation. Pseudomonas aeruginosa (PAO) is one of the most common pathogens causing lung injury, and the role of PAO‐infected alveolar fibroblasts in such a condition remains unclear.
Yue Zhou, Yangyang Xiao, Wei Liu, Xiaozhi Wang, Tao Wang, Qian Qi, Dong Zhang   +6 more
wiley   +1 more source