Results 11 to 20 of about 67,869 (268)

The Value of CXCL1, CXCL2, CXCL3, and CXCL8 as Potential Prognosis Markers in Cervical Cancer: Evidence of E6/E7 from HPV16 and 18 in Chemokines Regulation

open access: yesBiomedicines, 2023
Cervical cancer (CC) is a serious global health issue, and it is well-known that HPV infection is the main etiological factor that triggers carcinogenesis.
Leonardo Fernandez-Avila   +5 more
doaj   +1 more source

Discovery and pharmacophoric characterization of chemokine network inhibitors using phage-display, saturation mutagenesis and computational modelling

open access: yesNature Communications, 2023
CC and CXC-chemokines are the primary drivers of chemotaxis in inflammation, but chemokine network redundancy thwarts pharmacological intervention. Tick evasins promiscuously bind CC and CXC-chemokines, overcoming redundancy.
Serena Vales   +13 more
doaj   +1 more source

CC chemokines and receptors in osteoarthritis: new insights and potential targets

open access: yesArthritis Research & Therapy, 2023
Osteoarthritis (OA) is a prevalent degenerative disease accompanied by the activation of innate and adaptive immune systems-associated inflammatory responses.
Yuchen Zhang   +5 more
doaj   +1 more source

Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa fever. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
The pathogenesis of Lassa fever (LF), a hemorrhagic fever endemic to West Africa, remains unclear. We previously compared Lassa virus (LASV) with its genetically close, but nonpathogenic homolog Mopeia virus (MOPV) and demonstrated that the strong ...
Delphine Pannetier   +4 more
doaj   +1 more source

HIV protective KIR3DL1/S1-HLA-B genotypes influence NK cell-mediated inhibition of HIV replication in autologous CD4 targets. [PDF]

open access: yesPLoS Pathogens, 2014
Carriage of the genetic combination encoding a high expression inhibitory Killer Immunoglobulin-like Receptor (KIR)3DL1 with its ligand, HLA-B*57 (*h/*y+B*57) is associated with slower time to AIDS and better HIV viral load control than being a Bw6 ...
Rujun Song   +5 more
doaj   +1 more source

Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity

open access: yesFrontiers in Microbiology, 2019
Parapoxvirus of red deer in New Zealand (PVNZ) is a species of the Parapoxvirus genus that causes pustular dermatitis. We identified a cluster of genes in PVNZ that encode three unique chemokine-binding proteins (CBPs) namely ORF112.0, ORF112.3 and ...
Saeed Sharif   +7 more
doaj   +1 more source

CC-chemokine receptors: a potential therapeutic target for Trypanosoma cruzi-elicited myocarditis

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
The comprehension of the pathogenesis of Trypanosoma cruzi-elicited myocarditis is crucial to delineate new therapeutic strategies aiming to ameliorate the inflammation that leads to heart dysfunction, without hampering parasite control.
APMP Marino   +6 more
doaj   +1 more source

The atypical chemokine receptor-2 fine-tunes the immune response in herpes stromal keratitis

open access: yesFrontiers in Immunology, 2022
Herpes stromal keratitis (HSK) is a blinding corneal disease caused by herpes simplex virus-1 (HSV-1), a common pathogen infecting most of the world’s population.
Tian Yu   +9 more
doaj   +1 more source

Chemokines and immunity

open access: yesEinstein (São Paulo)
Chemokines are a large family of small cytokines and generally have low molecular weight ranging from 7 to 15kDa. Chemokines and their receptors are able to control the migration and residence of all immune cells.
Diana Carolina Torres Palomino   +1 more
doaj   +1 more source

Serum CC Chemokines as Potential Biomarkers for the Diagnosis of Major Depressive Disorder

open access: yesPsychology Research and Behavior Management, 2022
Wenfan Gao,1– 4,* Yayun Xu,5– 7,* Jun Liang,1– 4 Yanhong Sun,1– 4 Yuanyuan Zhang,1– 4 Feng Shan,1– 4 Jinfang Ge,6– 8 Qingrong Xia1– 4 1Affiliated Psychological Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2Department ...
Gao W   +7 more
doaj  

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