Results 21 to 30 of about 99,546 (246)

Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa fever. [PDF]

PLoS Neglected Tropical Diseases, 2014
The pathogenesis of Lassa fever (LF), a hemorrhagic fever endemic to West Africa, remains unclear. We previously compared Lassa virus (LASV) with its genetically close, but nonpathogenic homolog Mopeia virus (MOPV) and demonstrated that the strong ...
Delphine Pannetier, Stéphanie Reynard, Marion Russier, Xavier Carnec, Sylvain Baize   +4 more
doaj   +1 more source

The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3 [PDF]

Proceedings of the National Academy of Sciences, 1998
We cloned the mouse homologue of the chemokine receptor CXCR3, which is located in mouse chromosome X. We screened a large panel of chemokines for their ability to induce a calcium flux in mouse CXCR3-transfected cells and identified a new ligand for this receptor, the recently reported CC chemokine 6Ckine. This represents an example of a CC chemokine,
H, Soto, W, Wang, R M, Strieter, N G, Copeland, D J, Gilbert, N A, Jenkins, J, Hedrick, A, Zlotnik   +7 more
openaire   +2 more sources

HIV protective KIR3DL1/S1-HLA-B genotypes influence NK cell-mediated inhibition of HIV replication in autologous CD4 targets. [PDF]

PLoS Pathogens, 2014
Carriage of the genetic combination encoding a high expression inhibitory Killer Immunoglobulin-like Receptor (KIR)3DL1 with its ligand, HLA-B*57 (*h/*y+B*57) is associated with slower time to AIDS and better HIV viral load control than being a Bw6 ...
Rujun Song, Irene Lisovsky, Bertrand Lebouché, Jean-Pierre Routy, Julie Bruneau, Nicole F Bernard   +5 more
doaj   +1 more source

Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity

Frontiers in Microbiology, 2019
Parapoxvirus of red deer in New Zealand (PVNZ) is a species of the Parapoxvirus genus that causes pustular dermatitis. We identified a cluster of genes in PVNZ that encode three unique chemokine-binding proteins (CBPs) namely ORF112.0, ORF112.3 and ...
Saeed Sharif, Norihito Ueda, Yoshio Nakatani, Lyn M. Wise, Sheree Clifton, Zabeen Lateef, Andrew A. Mercer, Stephen B. Fleming   +7 more
doaj   +1 more source

CC-chemokine receptors: a potential therapeutic target for Trypanosoma cruzi-elicited myocarditis

Memorias do Instituto Oswaldo Cruz, 2005
The comprehension of the pathogenesis of Trypanosoma cruzi-elicited myocarditis is crucial to delineate new therapeutic strategies aiming to ameliorate the inflammation that leads to heart dysfunction, without hampering parasite control.
APMP Marino, AA Silva, PVA Santos, LMO Pinto, RT Gazinelli, MM Teixeira, J Lannes-Vieira   +6 more
doaj   +1 more source

Chemokines and immunity

Einstein (São Paulo)
Chemokines are a large family of small cytokines and generally have low molecular weight ranging from 7 to 15kDa. Chemokines and their receptors are able to control the migration and residence of all immune cells.
Diana Carolina Torres Palomino, Luciana Cavalheiro Marti   +1 more
doaj   +1 more source

Serum CC Chemokines as Potential Biomarkers for the Diagnosis of Major Depressive Disorder

Psychology Research and Behavior Management, 2022
Wenfan Gao,1– 4,* Yayun Xu,5– 7,* Jun Liang,1– 4 Yanhong Sun,1– 4 Yuanyuan Zhang,1– 4 Feng Shan,1– 4 Jinfang Ge,6– 8 Qingrong Xia1– 4 1Affiliated Psychological Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2Department ...
Gao W, Xu Y, Liang J, Sun Y, Zhang Y, Shan F, Ge J, Xia Q   +7 more
doaj  

The atypical chemokine receptor-2 fine-tunes the immune response in herpes stromal keratitis

Frontiers in Immunology, 2022
Herpes stromal keratitis (HSK) is a blinding corneal disease caused by herpes simplex virus-1 (HSV-1), a common pathogen infecting most of the world’s population.
Tian Yu, Tian Yu, Fabian Schuette, Maria Christofi, John V. Forrester, John V. Forrester, John V. Forrester, Gerard J. Graham, Lucia Kuffova, Lucia Kuffova   +9 more
doaj   +1 more source

CC chemokines Modulate Immune responses in Pulmonary Hypertension

Journal of Advanced Research
Background: Pulmonary hypertension (PH) represents a progressive condition characterized by the remodeling of pulmonary arteries, ultimately culminating in right heart failure and increased mortality rates. Substantial evidence has elucidated the pivotal
Qian Yan, Shasha Liu, Yang Sun, Chen Chen, Yantao Yang, Songwei Yang, Meiyu Lin, Junpeng Long, Yuting Lin, Jinping Liang, Qidi Ai, Naihong Chen   +11 more
doaj   +1 more source

Enhanced Levels of Chemokines and Their Receptors in the Colon of Microscopic Colitis Patients Indicate Mixed Immune Cell Recruitment

Mediators of Inflammation, 2015
Microscopic colitis (MC), comprising collagenous colitis (CC) and lymphocytic colitis (LC), is a common cause of chronic diarrhea. Various immune cell infiltrations in the epithelium and lamina propria are seen in MC immunopathology. We compared gene and
Sezin Günaltay, Ashok Kumar Kumawat, Nils Nyhlin, Johan Bohr, Curt Tysk, Olof Hultgren, Elisabeth Hultgren Hörnquist   +6 more
doaj   +1 more source