Results 21 to 30 of about 603,906 (283)
Gastroenterology & Endoscopy, 2023 Pancreatic adenocarcinoma (PAAD), one of the most aggressive and lethal malignant tumors, is correlated with increased morbidity and mortality. CC chemokines can modulate the infiltration of immune cells and affect the clinical outcome of cancer patients.
Xinyuan Liu +7 more
doaj +1 more source
BMC Urology, 2021 Background Urothelial bladder cancer (BC) is one of the most prevalent malignancies with high mortality and high recurrence rate. Angiogenesis, tumor growth and metastasis of multiple cancers are partly modulated by CC chemokines. However, we know little
Yuxin Li +8 more
doaj +1 more source
Vaccines, 2022 COVID-19 is one of the progressive viral pandemics that originated from East Asia. COVID-19 or SARS-CoV-2 has been shown to be associated with a chain of physio-pathological mechanisms that are basically immunological in nature.
Mojgan Noroozi Karimabad +9 more
doaj +1 more source
Virology Journal, 2021 It has been reported that polyomaviruses are the microbes which can be a cause of several human pathological conditions including cancers, nephropathy, progressive multifocal leukoencephalopathy and gynaecological disease. Although investigators proposed
Mohammad Hassan Mohammadi +1 more
doaj +1 more source
Molecular determinants for CC-chemokine recognition by a poxvirus CC-chemokine inhibitor [PDF]
Proceedings of the National Academy of Sciences, 2001 Poxviruses express a family of secreted proteins that bind with high affinity to chemokines and antagonize the interaction with their cognate G protein-coupled receptors (GPCRs). These viral inhibitors are novel in structure and, unlike cellular chemokine receptors, are able to specifically interact with most, if not all, CC-chemokines.
B T, Seet +5 more
openaire +2 more sources
The CC Chemokine Eotaxin (CCL11) Is a Partial Agonist of CC Chemokine Receptor 2b [PDF]
Journal of Biological Chemistry, 2001 Despite sharing considerable homology with the members of the monocyte chemoattractant protein (MCP) family, the CC chemokine eotaxin (CCL11) has previously been reported to signal exclusively via the receptor CC chemokine receptor 3 (CCR3). Using the monocyte cell line THP-1, we investigated the relative abilities of eotaxin and MCPs 1-4 to induce ...
R, Martinelli +4 more
openaire +2 more sources
Cancer Cell International, 2021 Background The tumor microenvironment (TME) has received an increasing amount of attention. CXC chemokines can regulate immune cell transport and tumor cell activity to exert anti-tumor immunity.
Weina Kong +7 more
doaj +1 more source
iScience, 2022 Summary: Inflammatory cytokines and chemokines (CC) drive COVID-19 pathology. Yet, patients with similar circulating CC levels present with different disease severity. Here, we determined 171 microRNAomes from 58 hospitalized COVID-19 patients (Cohort 1)
Julie C. Wilson +20 more
doaj +1 more source
Nature Communications, 2023 CC and CXC-chemokines are the primary drivers of chemotaxis in inflammation, but chemokine network redundancy thwarts pharmacological intervention. Tick evasins promiscuously bind CC and CXC-chemokines, overcoming redundancy.
Serena Vales +13 more
doaj +1 more source
Biomedicines, 2023 Cervical cancer (CC) is a serious global health issue, and it is well-known that HPV infection is the main etiological factor that triggers carcinogenesis.
Leonardo Fernandez-Avila +5 more
doaj +1 more source