Results 11 to 20 of about 603,906 (283)

The roles of CC chemokines in response to radiation

Radiation Oncology, 2022
Radiotherapy is an effective regimen for cancer treatment alone or combined with chemotherapy or immunotherapy. The direct effect of radiotherapy involves radiation-induced DNA damage, and most studies have focused on this area to improve the efficacy of
Lei Wang, Jizong Jiang, Yuan Chen, Qingzhu Jia, Qian Chu   +4 more
doaj   +3 more sources

CC Chemokines in Idiopathic Pulmonary Fibrosis: Pathogenic Role and Therapeutic Potential

Biomolecules, 2023
Idiopathic pulmonary fibrosis (IPF), characterized by progressive worsening of dyspnea and irreversible decline in lung function, is a chronic and progressive respiratory disease with a poor prognosis.
Shanshan Liu, Chang Liu, Qianrong Wang, Suosi Liu, Jiali Min   +4 more
doaj   +2 more sources

Hypoxia Alters the Expression of CC Chemokines and CC Chemokine Receptors in a Tumor–A Literature Review [PDF]

International Journal of Molecular Sciences, 2020
Hypoxia, i.e., oxygen deficiency condition, is one of the most important factors promoting the growth of tumors. Since its effect on the chemokine system is crucial in understanding the changes in the recruitment of cells to a tumor niche, in this review we have gathered all the available data about the impact of hypoxia on β chemokines.
Jan Korbecki, Klaudyna Kojder, Katarzyna Barczak, Donata Simińska, Izabela Gutowska, Dariusz Chlubek, Irena Baranowska-Bosiacka   +6 more
openaire   +3 more sources

CC chemokines Modulate Immune responses in Pulmonary Hypertension

Journal of Advanced Research
Background: Pulmonary hypertension (PH) represents a progressive condition characterized by the remodeling of pulmonary arteries, ultimately culminating in right heart failure and increased mortality rates. Substantial evidence has elucidated the pivotal
Qian Yan, Shasha Liu, Yang Sun, Chen Chen, Yantao Yang, Songwei Yang, Meiyu Lin, Junpeng Long, Yuting Lin, Jinping Liang, Qidi Ai, Naihong Chen   +11 more
doaj   +2 more sources

The Role of CC-Chemokines in the Regulation of Angiogenesis [PDF]

International Journal of Molecular Sciences, 2016
Angiogenesis, the formation of new blood vessels, is critical for survival and in the regenerative response to tissue injury or ischemia. However, in diseases such as cancer and atherosclerosis, inflammation can cause unregulated angiogenesis leading to excessive neovascularization, which exacerbates disease.
Anisyah Ridiandries, Joanne Tan, Christina Bursill   +2 more
openaire   +5 more sources

Re: Chemokines in Cancer

Journal of Urological Surgery, 2016
Chemokines are chemotactic cytokines that regulate the trafficking and positioning of cells by activating the seven-transmembrane spanning G protein-coupled chemokine receptors (GPCR) or non G protein-coupled seven-transmembrane spanning receptors called
Fehmi Narter
doaj   +2 more sources

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection [PDF]

FEBS Open Bio
Chemokines and their cognate receptors are central orchestrators of the immune response to Mycobacterium tuberculosis (Mtb) infection. While their overall significance in tuberculosis (TB) is well‐established, this review synthesizes recent advances to ...
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
doaj   +2 more sources

Neuronal CC chemokines: the distinct roles of CCL21 and CCL2 in neuropathic pain

Frontiers in Cellular Neuroscience, 2014
The development of neuropathic pain in response to peripheral nerve lesion for a large part depends on microglia located at the dorsal horn of the spinal cord.
Knut eBiber, Knut eBiber, Erik eBoddeke
doaj   +2 more sources

Blockade of CC chemokine receptor 2 suppresses pancreatic cancer progression through the interaction with macrophages in the tumor microenvironment [PDF]

Scientific Reports
Pancreatic ductal adenocarcinoma (PDAC) is the most intractable cancer, demonstrating abundant stroma in the tumor microenvironment (TME). Previously, we reported that CXC chemokines contributed to the progression of PDAC through tumor-stromal ...
Gen Kimura, Hideaki Ijichi, Makoto Sano, Genso Notoya, Koji Miyabayashi, Ryota Takahashi, Takahiro Kishikawa, Mitsuhiro Fujishiro   +7 more
doaj   +2 more sources

Human Chemokines as Antimicrobial Peptides with Direct Parasiticidal Effect on Leishmania mexicana In Vitro [PDF]

, 2013
Chemokines and chemokine receptor-mediated effects are important mediators of the immunological response and cure in human leishmaniasis. However, in addition to their signalling properties for leukocytes, many chemokines have also been shown to act ...
Collin, Mattias, Bates, Paul, Shannon, Oonagh, Söbirk, Sara K, Egesten, Arne, Mörgelin, Matthias   +5 more
core   +5 more sources