Results 231 to 240 of about 455,922 (328)

CD40 Ligand-CD40 Interaction Induces Chemokines in Cervical Carcinoma Cells in Synergism with IFN-γ [PDF]

, 1999
Andreas Altenburg, Stephan Baldus, Hans Smola, Herbert Pfister, Sigrun Hess   +4 more
openalex   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Checkpoint Kinase 1 Inhibitor Combined with Low Dose Hydroxyurea Promotes ATM-Activated NF-κB-Dependent Pro-Inflammatory Chemokine Expression in Melanomas. [PDF]

Cancers (Basel)
Goh NLL, Abdul Rahim NJ, Bhatt R, Ong SE, Lim KY, Gandini A, Zeng Z, Kumari S, Gabrielli B.   +8 more
europepmc   +1 more source

Up-Regulation of CCR2 Chemokine Receptor Expression and Increased Susceptibility to the Multitropic HIV Strain 89.6 in Monocytes Exposed to Glucocorticoid Hormones [PDF]

, 1999
Giselle Pentón‐Rol, Manuela Cota, Nadia Polentarutti, Walter Luini, Sergio Bernasconi, Alessandro Borsatti, Antonio Sica, Gregory J. LaRosa, Silvano Sozzani, Guido Poli, Alberto Mantovani   +10 more
openalex   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Therapeutic impact of human trophoblast stem cells in peritoneal and pneumonia-induced sepsis in mice. [PDF]

Stem Cell Res Ther
Hwang N, Li G, Murzin E, Mays CJ, Lederer JA, Liu X, Perrella MA.   +6 more
europepmc   +1 more source

Localization of the gene for the human MIG cytokine on chromosome 4q21 adjacent to INP10 reveals a chemokine “mini-cluster” [PDF]

, 1996
H.-H Lee, Joshua Μ. Farber
openalex   +1 more source

Cytokine Engineering Approaches for Regenerative Medicine

Advanced Therapeutics, EarlyView.
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley   +1 more source

Fatty Acids and Inflammatory Protein Biomarkers From Coronavirus Disease 2019 Patients. [PDF]

Immun Inflamm Dis
Bala N, Habib AH, Kozuch M, Denslow ND, Dhaliwal NS, Owings AH, Glover SC, Alli AA.   +7 more
europepmc   +1 more source

Enhancing the Effectiveness of Chemotherapy in Osteosarcoma by Targeting Tumour‐Associated Macrophages (TAMs) through STING Activation

Advanced Therapeutics, EarlyView.
Osteosarcoma isa highly aggressive bone cancer with an immunosuppressive tumor microenvironment that limits immunotherapy. This study explores STING pathway activation to reprogram tumor‐associated macrophages into a tumoricidal M1‐like phenotype and enhance doxorubicin efficacy. Results show that doxorubicin alone failed to activate the STING pathway,
Jordan C. O'Donoghue, Amanda Guitián‐Caamaño, Maeve Boyce, Fiona E. Freeman   +3 more
wiley   +1 more source