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Progress in structure-based drug development targeting chemokine receptors. [PDF]
Wang J+5 more
europepmc +1 more source
Chemokine System Changes Drive Age-Related Macular Degeneration and Influence Treatment Outcomes. [PDF]
Thomsen AK+6 more
europepmc +1 more source
Microglial activation is inhibited by selective anti-seizure medications. [PDF]
Platow RJ+5 more
europepmc +1 more source
Intermediate Monocytes and High Levels of Chemokine CCL3 Are Associated With Increased Risk of Atrial Fibrillation in the General Population. [PDF]
Sveen KA+10 more
europepmc +1 more source
AbstractThe chemokines and their receptors are a superfamily of small secreted molecules that control the migration of many cell types in the body. Several years ago it became clear that some chemokines and receptors regulate the migration of certain cells in the lymphoid system, and this raised the possibility that chemokines could also control the ...
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Chemokines, chemokine receptors and hematopoiesis
Immunological Reviews, 2000Hematopoiesis during steady state conditions is regulated and finely tuned by a network of cytokines and their effects on hematopoietic stem and progenitor cells and on accessory cells that influence the stem and progenitor cells. Amongst the numerous cytokines implicated in this regulation are members of the CC, CXC and C family of chemokines.
Hal E. Broxmeyer+2 more
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Cytokine & Growth Factor Reviews, 2001
Although chemokines were originally defined as host defense proteins it is now clear that their repertoire of functions extend well beyond this role. For example chemokines such as MGSA have growth regulatory properties while members of the CXC chemokine family can be mediators or inhibitors of angiogenesis and may be important targets for oncology ...
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Although chemokines were originally defined as host defense proteins it is now clear that their repertoire of functions extend well beyond this role. For example chemokines such as MGSA have growth regulatory properties while members of the CXC chemokine family can be mediators or inhibitors of angiogenesis and may be important targets for oncology ...
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Chemokines and Chemokine Receptors
2001The recruitment of cells to sites of inflammation is an essential component of the host inflammatory response. Cell recruitment relies on the coordinated action of cell activation, cell adhesion, chemoattraction, and transmigration across the endothelial barrier.
James A. MacLean, Andrew D. Luster
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