Results 61 to 70 of about 70,358 (244)

Study protocol: Randomized controlled trial of web-based decision support tools for high-risk women and healthcare providers to increase breast cancer chemoprevention

Contemporary Clinical Trials Communications, 2019
Background: Chemoprevention using selective estrogen receptor modulators and aromatase inhibitors has been shown to reduce invasive breast cancer incidence in high-risk women.
Katherine D. Crew, Thomas B. Silverman, Alejandro Vanegas, Meghna S. Trivedi, Jill Dimond, Jennie Mata, Margaret Sin, Tarsha Jones, Mary Beth Terry, Wei-Yann Tsai, Rita Kukafka   +10 more
doaj   +1 more source

Associations Between Climate‐Sensitive Nutrients, Clinical Malaria, and Anaemia Among Young Children in Rural Burkina Faso: An Analysis of Baseline Data From a Cluster‐Randomised Controlled Trial

Tropical Medicine &International Health, Volume 31, Issue 2, Page 181-189, February 2026.
ABSTRACT Objective Malaria and anaemia are significant public health challenges among young children in Burkina Faso, with complex interactions between climate variability, food security, and nutrient deficiencies. This study aimed to identify the malariometric profile and nutrient patterns among young children and to determine the associations of ...
Adi Lukas Kurniawan, Maria Virginia Borga, Fanta Zerbo, Carol Akinyi Abidha, Anais Gonnet, Raissa Sorgho, Boubacar Coulibaly, Ali Sié, Ina Danquah   +8 more
wiley   +1 more source

DNA polymerase β deficiency promotes the occurrence of esophageal precancerous lesions in mice

Neoplasia: An International Journal for Oncology Research, 2021
Esophageal mucosa undergoes mild, moderate, severe dysplasia, and other precancerous lesions and eventually develops into carcinoma in situ, and understanding the developmental progress of esophageal precancerous lesions is beneficial to prevent them ...
Jiace Qin, Yanyan Zhu, Yongwei Ding, Tingting Niu, Yangyang Zhang, Huiting Wu, Lili Zhu, Baoyin Yuan, Yan Qiao, Jing Lu, Kangdong Liu, Ziming Dong, Ge Jin, Xinhuan Chen, Jimin Zhao   +14 more
doaj   +1 more source

A high-fat diet containing whole walnuts (Juglans regia) reduces tumour size and growth along with plasma insulin-like growth factor 1 in the transgenic adenocarcinoma of the mouse prostate model. [PDF]

, 2012
Prostate cancer (PCa) has been linked to fat intake, but the effects of both different dietary fat levels and types remain inconsistent and incompletely characterised.
Cross, Carroll E, Davis, Paul A, Gohil, Kishorchandra, Khan, Imran H, Kim, Hyunsook, Vasu, Vihas T, Yokoyama, Wallace   +6 more
core   +1 more source

Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli, Seshasai Srinivasan, Amin Reza Rajabzadeh   +2 more
wiley   +1 more source

Phthalocyanine aggregates as semiconductor-like photocatalysts for hypoxic-tumor photodynamic immunotherapy

Nature Communications
Photodynamic immunotherapy (PIT) has emerged as a promising approach for efficient eradication of primary tumors and inhibition of tumor metastasis. However, most of photosensitizers (PSs) for PIT exhibit notable oxygen dependence.
Hao Liu, Ziqing Li, Xiaojun Zhang, Yihui Xu, Guoyan Tang, Zhaoxin Wang, Yuan-Yuan Zhao, Mei-Rong Ke, Bi-Yuan Zheng, Shuping Huang, Jian-Dong Huang, Xingshu Li   +11 more
doaj   +1 more source

OA-183 Dynamic of molecular and resistance markers prevalence of Plasmodium falciparum during the seasonal malaria chemoprevention campaign in school aged children in Bandiagara, Mali [PDF]

, 2023
Karim Traoré, Ali Thera, Drissa Coulibaly, Abdoulaye K. Koné, S. Traoré, Kindie Kouriba, Moussa Djimdé, Guillaume Bonot, Anne‐Lise Bienvenu, Stéphane Picot, Mahamadou A. Théra   +10 more
openalex   +1 more source

Natural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy

Food Frontiers, Volume 7, Issue 1, January 2026.
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli, Anna Maria Posadino, Roberta Giordo, Antonio Barberis, Ylenia Spissu, Redouane Lemoui, William N. Setzer, Javad Sharifi‐Rad, Gianfranco Pintus   +8 more
wiley   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, Volume 7, Issue 1, January 2026.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Orchestrated Cu2+-coordinated tetracycline-porphyrin self-assembly remodels tumor microenvironment for photo-enhanced immuno-chemodynamic therapy

Journal of Nanobiotechnology
Reactive oxygen species (ROS)-based nanodynamic therapy is emerging as a promising approach for tumor treatment, particularly in eliciting immune responses for tumor immunotherapy.
Xianbin Sun, Xinyi Wang, Xudong Li, Ya Wang, Ruofei Xu, Xinyi Shen, Ding Tan, Jingjing Liao, Haijun Chen, Yu Gao, Jianping Zheng   +10 more
doaj   +1 more source