Results 71 to 80 of about 26,309 (262)

Effect of novel metabotropic glutamate receptor 5 antagonist on gastroesophageal reflux in dogs during anaesthesia

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives Gastroesophageal reflux during anaesthesia is a common event occurring in dogs with the potential to cause oesophageal injury and aspiration pneumonia. The objective of the current study was to evaluate the effect of the novel metabotropic glutamate receptor 5 antagonist TT001 on gastroesophageal reflux during anaesthesia in dogs using two ...
A. Glovéus   +4 more
wiley   +1 more source

PULMONARY CHEMORECEPTORS [PDF]

open access: yesQuarterly Journal of Experimental Physiology and Cognate Medical Sciences, 1963
The existence of a chemoreceptor mechanism supplied by the pulmonary artery was demonstrated in the following manner.In anæsthetized cats or rabbits the main pulmonary artery was cannulated through the right ventricle. The right pulmonary artery was tied and the left pulmonary artery cannulated approximately 0·5 cm. from the bifurcation.
Helen N. Duke   +3 more
openaire   +1 more source

Sex differences in loop gain measured via superimposed end‐expiratory breath holds and inspired steady‐state hypoxia

open access: yesExperimental Physiology, EarlyView.
Abstract Acute low oxygen exposure (hypoxia) elicits a hypoxic ventilatory response (HVR), which increases ventilation and mitigates hypoxaemia. During sustained exposure to hypoxia, ventilatory acclimatization increases peripheral chemoreflex (HVR) sensitivity or chemoreflex loop gain (LG).
Benjamin W. L. MacKenzie   +3 more
wiley   +1 more source

Widespread depolarization during expiration: A source of respiratory drive? [PDF]

open access: yes, 2014
Respiration influences various pacemakers and rhythms of the body during inspiration and expiration but the underlying mechanisms are relatively unknown.
Barnes, Vernon A.   +3 more
core  

Modulation of cerebral blood flow and cognition by hyperthermia and hypoxia: An electroencephalographic event‐related potentials perspective

open access: yesExperimental Physiology, EarlyView.
Abstract Cerebral blood flow (CBF) is essential for sustaining neuronal metabolism and cognitive performance; however, the precise relationship between perfusion and cognition remains unclear. Although ageing and disease are associated with progressive declines in CBF and cognitive impairment, the acute effects of altered CBF under environmental ...
Hiroki Nakata   +2 more
wiley   +1 more source

Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells [PDF]

open access: yes, 2003
Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from inhibition of O2 -regulated K+ channels. However, the mechanisms involved in the detection of changes of O2 tension are unknown.
García Fernández, María   +3 more
core   +2 more sources

Nitric oxide and carotid body chemoreception

open access: yesBiological Research, 2001
Nitric oxide (NO) has been proposed as an inhibitory modulator of carotid body chemosensory responses to hypoxia. It is believed that NO modulates carotid chemoreception by several mechanisms, which include the control of carotid body vascular tone and ...
RODRIGO ITURRIAGA
doaj  

Short-Term Sustained Hypoxia Elevates Basal and Hypoxia-Induced Ventilation but Not the Carotid Body Chemoreceptor Activity in Rats

open access: yesFrontiers in Physiology, 2018
Exposure to chronic sustained hypoxia (SH), as experienced in high altitudes, elicits an increase in ventilation, named ventilatory acclimatization to hypoxia (VAH).
Karine C. Flor   +5 more
doaj   +1 more source

Time‐course analysis of cerebral circulation and cardiorespiratory responses to acute central blood volume reduction in healthy young males

open access: yesExperimental Physiology, EarlyView.
Abstract Central blood volume (CBV) reduction challenges circulatory and respiratory homeostasis, particularly during the initial compensatory phase (0–2 min), when rapid physiological adaptations occur. In this study, we examined dynamic cardiorespiratory responses to CBV reduction using lower‐body negative pressure (LBNP) in 11 healthy young males ...
Marina Feeley   +7 more
wiley   +1 more source

The effect of combined glutamate receptor blockade in the NTS on the hypoxic ventilatory response in awake rats differs from the effect of individual glutamate receptor blockade. [PDF]

open access: yes, 2014
Ventilatory acclimatization to hypoxia (VAH) increases the hypoxic ventilatory response (HVR) and causes persistent hyperventilation when normoxia is restored, which is consistent with the occurrence of synaptic plasticity in acclimatized animals ...
Carr, John A   +3 more
core   +2 more sources

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