Results 61 to 70 of about 60,935 (266)
British Journal of Clinical Pharmacology, EarlyView.Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post +4 more
wiley +1 more source
Structure of bacterial cytoplasmic chemoreceptor arrays and implications for chemotactic signaling [PDF]
, 2014 Most motile bacteria sense and respond to their environment through a transmembrane chemoreceptor array whose structure and function have been well-studied, but many species also contain an additional cluster of chemoreceptors in their cytoplasm ...
Armitage, Judith P. +9 more
core +2 more sources
Purines and Carotid Body: New Roles in Pathological Conditions
Frontiers in Pharmacology, 2017 It is known that adenosine and adenosine-5′-triphosphate (ATP) are excitatory mediators involved in carotid body (CB) hypoxic signaling. The CBs are peripheral chemoreceptors classically defined by O2, CO2, and pH sensors.
Silvia V. Conde +2 more
doaj +1 more source
Emergence of collective propulsion through cell-cell adhesion [PDF]
Phys. Rev. E 97, 042413 (2018), 2017 The mechanisms driving the collective movement of cells remain poorly understood. To contribute toward resolving this mystery, a model was formulated to theoretically explore the possible functions of polarized cell-cell adhesion in collective cell migration. The model consists of an amoeba cell with polarized cell-cell adhesion, which is controlled by
arxiv +1 more source
Neural regulation of cardiovascular response to exercise: role of central command and peripheral afferents [PDF]
, 2014 During dynamic exercise, mechanisms controlling the cardiovascular apparatus operate to provide adequate oxygen to fulfill metabolic demand of exercising muscles and to guarantee metabolic end-products washout.
Crisafulli, A +5 more
core +8 more sources
British Journal of Pharmacology, EarlyView.Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio +5 more
wiley +1 more source
Chemotaxis cluster 1 proteins form cytoplasmic arrays in Vibrio cholera and are stabilized by a double signaling domain receptor DosM [PDF]
, 2016 Nearly all motile bacterial cells use a highly sensitive and adaptable sensory system to detect changes in nutrient concentrations in the environment and guide their movements toward attractants and away from repellents.
Briegel, Ariane +5 more
core +3 more sources
Fernando De Castro and the discovery of the arterial chemoreceptors
Frontiers in Neuroanatomy, 2014 When De Castro entered the carotid body (CB) field, the organ was considered to be a small autonomic ganglion, a gland, a glomus or glomerulus, or a paraganglion.
Constancio eGonzalez +11 more
doaj +1 more source
Asymmetric polar localization dynamics of the serine chemoreceptor protein Tsr in Escherichia coli. [PDF]
PLoS ONE, 2018 The spatial location of proteins in living cells can be critical for their function. For example, the E. coli chemotaxis machinery is localized to the cell poles.
Dongmyung Oh +5 more
doaj +1 more source
Epilepsia, EarlyView.Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder +4 more
wiley +1 more source