Results 151 to 160 of about 64,721 (205)

In vivo functional screens reveal <i>KEAP1</i> loss as a driver of chemoresistance in small cell lung cancer. [PDF]

open access: yesSci Adv
Brumage L   +16 more
europepmc   +1 more source

Tumor–Stroma Ratio in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta‐Analysis

open access: yesOral Diseases, EarlyView.
ABSTRACT Background Tumor‐stroma ratio (TSR) has been recognized as a significant prognostic factor in various cancers. This systematic review evaluates the role of TSR in head and neck squamous cell carcinoma (HNSCC) and its association with patient outcomes such as overall survival (OS), disease‐free survival (DFS), disease‐specific survival (DSS ...
Gennaro Musella   +6 more
wiley   +1 more source

Photodynamic priming overcomes platinum resistance from short‐term exposure to select perfluoroalkyl substances in endometrial cancer cell lines

open access: yesPhotochemistry and Photobiology, EarlyView.
PFAS are widespread environmental contaminants that are associated with platinum resistance and mitochondrial membrane hyperpolarization in endometrial cancer cell lines. Photodynamic therapy, using BPD or ALA‐PpIX, in combination with low‐dose carboplatin overcomes PFAS‐induced platinum resistance in endometrial cancer cell lines.
Brittany P. Rickard   +7 more
wiley   +1 more source

Identification of potential cell surface targets in patient‐derived cultures toward photoimmunotherapy of high‐grade serous ovarian cancer

open access: yesPhotochemistry and Photobiology, EarlyView.
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina   +3 more
wiley   +1 more source

USP9X integrates TGF-β and hypoxia signalings to promote ovarian cancer chemoresistance via HIF-2α-maintained stemness. [PDF]

open access: yesCell Death Dis
Zhang Z   +11 more
europepmc   +1 more source

Classification and Prognostication of B‐Cell and T‐Cell Multicentric Lymphoma in Dogs Using Serum MicroRNAs

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine multicentric lymphoma is a common malignancy in dogs. It often responds well to initial chemotherapy but frequently relapses and has a poor response to subsequent treatment. B‐cell (BCL) and T‐cell (TCL) lymphomas differ in both their prognoses and chemotherapeutic treatment protocols.
Latasha Ludwig   +6 more
wiley   +1 more source

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