In vivo functional screens reveal <i>KEAP1</i> loss as a driver of chemoresistance in small cell lung cancer. [PDF]
Brumage L+16 more
europepmc +1 more source
Tumor–Stroma Ratio in Head and Neck Squamous Cell Carcinoma: A Systematic Review and Meta‐Analysis
ABSTRACT Background Tumor‐stroma ratio (TSR) has been recognized as a significant prognostic factor in various cancers. This systematic review evaluates the role of TSR in head and neck squamous cell carcinoma (HNSCC) and its association with patient outcomes such as overall survival (OS), disease‐free survival (DFS), disease‐specific survival (DSS ...
Gennaro Musella+6 more
wiley +1 more source
Retraction notice: "MicroRNA-19b Downregulates NR3C1 and Enhances Oxaliplatin Chemoresistance in Colon Cancer via the PI3K/AKT/mTOR Pathway". [PDF]
europepmc +1 more source
Induction of ferroptosis in oxaliplatin-resistant colorectal cancer cells by extract from <i>Actinidia chinensis</i> Planch radix. [PDF]
Lu J, Wang Y, Cui W, Ma C.
europepmc +1 more source
PFAS are widespread environmental contaminants that are associated with platinum resistance and mitochondrial membrane hyperpolarization in endometrial cancer cell lines. Photodynamic therapy, using BPD or ALA‐PpIX, in combination with low‐dose carboplatin overcomes PFAS‐induced platinum resistance in endometrial cancer cell lines.
Brittany P. Rickard+7 more
wiley +1 more source
Hyaluronan-mediated motility receptor-mediated aerobic glycolysis enhances stem-like properties and chemoresistance in lung adenocarcinoma. [PDF]
Yu W+6 more
europepmc +1 more source
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina+3 more
wiley +1 more source
Expression of concern: "A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer" [eBioMedicine Volume 44, Pages 311-321 June 2019, 2147]. [PDF]
europepmc +1 more source
USP9X integrates TGF-β and hypoxia signalings to promote ovarian cancer chemoresistance via HIF-2α-maintained stemness. [PDF]
Zhang Z+11 more
europepmc +1 more source
ABSTRACT Canine multicentric lymphoma is a common malignancy in dogs. It often responds well to initial chemotherapy but frequently relapses and has a poor response to subsequent treatment. B‐cell (BCL) and T‐cell (TCL) lymphomas differ in both their prognoses and chemotherapeutic treatment protocols.
Latasha Ludwig+6 more
wiley +1 more source