Results 171 to 180 of about 133,761 (337)

One‐Stone‐Two‐Birds Carrier‐Free Nano‐Cocktail Enables Synergistic Eradication of Cancer Cells/Stem Cells in Breast Cancer Treatment

Exploration, EarlyView.
ABSTRACT Cancer stem cells (CSCs) are widely recognized as the culprits of chemoresistance, tumor metastasis, and relapse. Moreover, most chemotherapeutic drugs not only fail to eliminate CSCs effectively, but also induce the acquisition of stemness characteristics in non‐stem cancer cells. Herein, we propose a cancer cells/CSCs double‐killing modality
Tongyao Zhao, Yao Chen, Haimeng Yuan, Shuqian Yang, Hongyuan Zhang, Yuequan Wang, Shenwu Zhang, Qin Chen, Jin Sun, Zhonggui He, Cong Luo   +10 more
wiley   +1 more source

Chemoresistance of PRAME-expressing melanoma cell can be resolved with help of bortezomib

, 2019
V. A. Misyurin, Daria Kalenichenko, A. A. Rudakova, Yu. P. Finashutina, Н. А. Лыжко, В. В. Тихонова, Л. А. Кесаева, О. Н. Солопова, Anna Misyurina, А. Н. Великанов, М. А. Барышникова, A. V. Misyurin   +11 more
openalex   +2 more sources

Role of Long Non-Coding RNAs in the Chemoresistance of Gastric Cancer: A Systematic Review

, 2021
Zonglin Li, Muhan Lü, Yejiang Zhou, Linxia Xu, Yifan Jiang, Yi Liu, Xin Li, Min Song   +7 more
openalex   +2 more sources

Figure S1 from Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring [PDF]

, 2023
Jean Nakhle, Khattar Khattar, Tülin Özkan, Adel Boughlita, Daouda Abba Moussa, Amélie Darlix, Frédérique Lorcy, Valérie Rigau, Luc Bauchet, Sabine Gerbal‐Chaloin, Martine Daujat‐Chavanieu, Floriant Bellvert, Laurent Turchi, Thierry Virolle, Jean‐Philippe Hugnot, Nicolas Buisine, Mireille Galloni, Valérie Dardalhon, Anne‐Marie Rodriguez, Marie‐Luce Vignais   +19 more
openalex   +1 more source

Single-cell multi-omics elucidates the role of RPS27-RPS24 fusion gene in osteosarcoma chemoresistance and metabolic regulation

Cell Death Discovery
Osteosarcoma (OS) presents significant treatment challenges due to chemoresistance. This study explores the molecular mechanisms underlying chemoresistance in OS, focusing on the novel fusion gene RPS27-RPS24. Using single-cell multi-omics techniques, we
Zhiwei Tao, Pingan Zou, Zhengxu Yang, Tao Xiong, Zhi Deng, Qincan Chen   +5 more
doaj   +1 more source

The PIK3CA Mutation in Advanced Breast Cancer Chemoresistance and Recurrence [PDF]

Movchan Oleksii Volodimirovich, Smolanka Ivan Ivanovich, Lyashenko Andriy Oleksandrovich, Loboda Anton Dmitrovich, Dosenko Irina Viktorivna, Dosenko Irina Viktorivna, Ivankova Oksana Mykolaivna   +6 more
openalex   +1 more source

Advanced extracellular vesicle immunotherapy

FlexMat, EarlyView.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang, Yunfei Mu, Xianyue Ji, Xiaoting Jiang, Ruiheng Wang, Xianguang Ding, Lianhui Wang   +6 more
wiley   +1 more source

Retraction Note: RCC2 contributes to tumor invasion and chemoresistance to cisplatin in hepatocellular carcinoma [PDF]

Qingmin Chen, Peiqiang Jiang, Baoxing Jia, Yahui Liu, Ze Zhang   +4 more
openalex   +1 more source

Clinical validation of a DNA methylation biomarker associated with overall survival of relapsed ovarian cancer patients

International Journal of Cancer, EarlyView.
What's New? Most patients with ovarian cancer (OC) relapse after first‐line chemotherapy, and prognosis with second‐line treatment depends largely on the platinum‐free interval. However, reliable biomarkers to predict response to second‐line therapy remain lacking.
Muhammad Habiburrahman, Nahal Masrour, Naina Patel, Anna M. Piskorz, Robert Brown, James D. Brenton, Iain A. McNeish, James M. Flanagan   +7 more
wiley   +1 more source

Overexpressing lncRNA <em>SNHG16</em> inhibited HCC proliferation and chemoresistance by functionally sponging hsa-miR-93

, 2018
Fengfeng Xu, Guoqing Zha, Yanpeng Wu, Weilong Cai, Jian Ao   +4 more
openalex   +2 more sources