Results 211 to 220 of about 133,761 (337)

Supplementary Figure 3 from Novel Inhibitors of Cyclin-Dependent Kinases Combat Hepatocellular Carcinoma without Inducing Chemoresistance

, 2023
Christine Haider, Markus Grubinger, Eva Řezníčková, Thomas S. Weiß, Hans Rotheneder, Walter Miklos, Walter Berger, Radek Jorda, Marek Zatloukal, Tomáš Gucký, Miroslav Strnad, Vladimı́r Kryštof, Wolfgang Mikulits   +12 more
openalex   +1 more source

The 5‐Methylcytosine RNA Modification in Hepatitis B Virus‐Negative Hepatocellular Carcinoma: Insights From Long‐Read Nanopore Sequencing

Molecular Carcinogenesis, EarlyView.
ABSTRACT 5‐Methylcytosine (m5C) RNA modification contributes to tumor initiation and progression. However, its transcriptome‐wide distribution patterns and biological implications in hepatitis B virus (HBV)‐negative hepatocellular carcinoma (HCC) remain poorly understood.
Tianhan Sun, Liying Zhou, XiaoQing Li, Ryan Xiao, Gaoyuan Sun, Lili Zhang, Yifei Li, Wei Huang, Yayu Li, Lu Kuai, Xuanmei Luo, Hongyuan Cui, Meng Chen   +12 more
wiley   +1 more source

Hypoxic conditions confer chemoresistance to crizotinib but not to imatinib in chronic myeloid leukemia cells. [PDF]

Hematol Transfus Cell Ther
Avinery L, Regev D, Khamaisi H, Gopas J, Mahajna J.   +4 more
europepmc   +1 more source

Small molecule inhibition of Axl receptor tyrosine kinase potently suppresses multiple malignant properties of glioma cells [PDF]

, 2015
An, Qian, Birt, Matthew, Hafizi, Sassan, Pilkington, Geoffrey John, Vouri, Mikaella   +4 more
core   +2 more sources

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

GIPC1 Restrains the Progression and Chemoresistance of Colorectal Cancer by Regulating TTC7B/mTOR/NF-κB Axis. [PDF]

Int J Biol Sci
Gan D, Yang C, Shen X, Shi J, Wang R, Zhu L, Li H, Luo J, Zhao T, Li J, Song Y, Su H.   +11 more
europepmc   +1 more source

Figure S3 from Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring

, 2023
Jean Nakhle, Khattar Khattar, Tülin Özkan, Adel Boughlita, Daouda Abba Moussa, Amélie Darlix, Frédérique Lorcy, Valérie Rigau, Luc Bauchet, Sabine Gerbal‐Chaloin, Martine Daujat‐Chavanieu, Floriant Bellvert, Laurent Turchi, Thierry Virolle, Jean‐Philippe Hugnot, Nicolas Buisine, Mireille Galloni, Valérie Dardalhon, Anne‐Marie Rodriguez, Marie‐Luce Vignais   +19 more
openalex   +1 more source

Leukemia in Older Adults: Global, National, and Regional Disease Burden Patterns During 1990–2019 and Forecasted Trends to 2030

Medicine Advances, EarlyView.
After analyzing the burden of leukemia in the elderly aged 60–89 years from 1990 to 2019 using the Global Burden of Disease database, we found that although the burden of chronic myeloid leukemia has decreased over the past 30 years, the burden of other types of leukemia has continued to increase to varying degrees.
Jing Wei, Qijian Feng, Ziyuan Lu
wiley   +1 more source

Supplementary Figure S8 from Single-Cell Evolutionary Analysis Reveals Drivers of Plasticity and Mediators of Chemoresistance in Small Cell Lung Cancer

, 2023
Hannah Wollenzien, Yohannes Afeworki Tecleab, Robert Szczepaniak‐Sloane, Anthony Restaino, Michael S. Kareta   +4 more
openalex   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source