Results 231 to 240 of about 149,400 (379)

Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance

, 2006
Bao Hoang, Li Zhu, Yijiang Shi, Patrick Frost, Huajun Yan, Sanjai Sharma, Sherven Sharma, Lee Goodglick, Steven M. Dubinett, Alan Lichtenstein   +9 more
openalex   +2 more sources

Characterisation of pvmdr1 and pvdhfr genes associated with chemoresistance in Brazilian Plasmodium vivax isolates [PDF]

, 2009
Bianca Ervatti Gama, Natália K Almeida de Oliveira, José Maria de Souza, Cláudio Tadeu Daniel‐Ribeiro, Maria de Fátima Ferreira‐da‐Cruz   +4 more
openalex   +1 more source

Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation

Food Frontiers, EarlyView.
PDIA4 is significantly upregulated in response to nutrient overload in pancreatic β‐cells, resulting in aberrant ROS production, β‐cell failure, and diabetes. PDIA4 facilitates cancer development by inhibiting caspase‐mediatedcell death in cancer and promoting VEGF‐mediated protumoral immunity andangiogenesis in the tumor microenvironment, highlighting
Yi‐San Lee, Catherine Ortega, Tien‐Fen Kuo, Greta Yang, Wen‐Chin Yang   +4 more
wiley   +1 more source

Integrated Genome-Wide DNA Copy Number and Expression Analysis Identifies Distinct Mechanisms of Primary Chemoresistance in Ovarian Carcinomas [PDF]

, 2009
Dariush Etemadmoghadam, Anna deFazio, Rameen Beroukhim, Craig H. Mermel, Joshy George, Gad Getz, Richard W. Tothill, Aikou Okamoto, Maria B. Ræder, Paul R. Harnett, Stephen Lade, Lars A. Akslen, Anna V. Tinker, Bianca Locandro, Kathryn Alsop, Yoke-Eng Chiew, Nadia Traficante, Sián Fereday, Daryl Johnson, Stephen B. Fox, William R. Sellers, Mitsuyoshi Urashima, Helga B. Salvesen, Matthew Meyerson, David D.L. Bowtell   +24 more
openalex   +1 more source

CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness

Cell, 2018
Shicheng Su, Jianing Chen, H. Yao, Jiang Liu, Shubin Yu, Liyan Lao, Minghui Wang, Man-Li Luo, Yue Xing, Fei Chen, Di Huang, Jinghua Zhao, Linbin Yang, D. Liao, F. Su, Mengfeng Li, Qiang Liu, E. Song   +17 more
semanticscholar   +1 more source

Apoptosis regulators of the Bcl‐2 family play a key role in chemoresistance of cholangiocarcinoma organoids

International Journal of Cancer, EarlyView.
What's New? Poor prognosis in cholangiocarcinoma (CCA) is attributed to late diagnosis and intrinsic chemoresistance. In particular, resistance mechanisms that suppress apoptosis limit the effectiveness of gemcitabine‐based regimens, which remain the standard treatment.
Wunan Mi, Gilles S. van Tienderen, Shaojun Shi, Amy Broeders, Kathryn Monfils, Henk P. Roest, Luc J. W. van der Laan, Monique M. A. Verstegen   +7 more
wiley   +1 more source

AK4 promotes nasopharyngeal carcinoma metastasis and chemoresistance by activating NLRP3 inflammatory complex. [PDF]

Cell Death Dis
Liu SL, Yuan L, Sun XS, Xiao BB, Lan KQ, Lu ZJ, Lin DF, Li XY, Yan JJ, Yan SM, Chen QY, Tang LQ, Mai HQ.   +12 more
europepmc   +1 more source

Cancer Stem Cell Characterization in Olfactory Neuroblastoma Tissue

International Forum of Allergy &Rhinology, EarlyView.
Shivani Ramolia, Riley Larkin, Yvette Robbins, Diana C. Lopez, Wiem Lassoued, Sreenivasulu Gunti, James L. Gulley, Gary Gallia, Clint Allen, Nyall R. London Jr.   +9 more
wiley   +1 more source

Mass cytometric detection of homologous recombination proficiency in circulating tumor cells to predict chemoresistance of metastatic breast cancer patients

International Journal of Cancer, EarlyView.
What's New? Circulating tumor cells can offer insights into treatment responses and metastatic recurrence, but current analysis methods are limited. Here, the authors tested a newly developed mass cytometry panel comprising biomarkers such as γH2AX and RAD51 in longitudinally monitored metastatic breast cancer patients.
Kathrin Niedermayer, Henning Schäffler, Georgios Vlachos, Sara Greco, Kerstin Pfister, Barbara Volz, Leonie Ott, Hans Neubauer, Bernhard Polzer, André Koch, Sabine Riethdorf, Tanja Fehm, Wolfgang Janni, Thomas W. P. Friedl, Brigitte Rack, Ellen Heitzer, Fabienne Schochter, Lisa Wiesmüller   +17 more
wiley   +1 more source

Single-cell transcriptomics identify a chemotherapy-resistance related cluster overexpressed CLIC3 in ovarian cancer. [PDF]

Discov Oncol
Li Z, Li J, Li Y, Yi J, Zhao X, Yue W.
europepmc   +1 more source