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Chemotactic factors and renal inflammation
American Journal of Kidney Diseases, 1998The mechanisms of leukocyte entry into the kidney during inflammatory renal disease have recently received considerable attention. Chemotactic factors appear to play a central role in this process, not only by inducing leukocyte movement but also by enhancing endothelial and leukocyte adhesiveness and endothelial permeability.
Brad H. Rovin, LT Phan
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Are Growth Factors Chemotactic Agents?
Experimental Cell Research, 1995We report the first direct observation of chemotaxis in slowly moving malignant cells. Two sarcoma cell lines of different metastatic potential were used. In a direct-viewing chemotaxis chamber with two concentric wells, the pooled trajectories of highly malignant rat T15 cells were strongly biased toward the outer well which contained platelet-derived
Daniel Zicha, Graham Dunn
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Chemotactic factors for bovine leukocytes
American Journal of Veterinary Research, 1982SUMMARY An agarose method was used to determine the nature of chemotaxins for bovine leukocytes as related to coliform mastitis. Freshly collected bovine serum or plasma was frequently chemotactic, probably due to spontaneous complement activation. Fresh serum was always rendered chemotactic when activated with zymosan or when heat-killed or viable ...
E J, Carroll, R, Mueller, L, Panico
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The influence of chemotactic factors on neutrophil adhesiveness
Inflammation, 1978The ability of several chemotactic factors to alter polymorphonuclear neutrophil (PMN) adhesiveness to nylon fibers was studied. Partly purified bacterial chemotactic factor, the isolated chemotactic fragment of human C5, and the chemotactic synthetic tripeptide, formyl-methionyl-leucyl-phenylalanine, transiently enhanced the nylon fiber adhesiveness ...
Donald L. Kreutzer +2 more
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Lymphangiogenic and Chemotactic Factors in Conjunctival Melanoma
Ophthalmic Plastic & Reconstructive Surgery, 2016Purpose: The aim of this study was to evaluate expression patterns of known lymphangiogenic growth factors and chemokines in conjunctival melanoma, and to describe patterns of lymphatic vessel growth in these tumors. Methods: This was a retrospective chart review comprising 5 ...
César A. Briceño +2 more
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Factors involved in ‘Chemotactism’ of Leucocytes in vitro
Nature, 1951The polymorphonuclear leucocytes isolated from blood or an inflammatory exudate are able to respond to chemotactic stimuli (‘tactism’). This property is readily demonstrated by the following technique1. A suspension of starch granules, isolated from potatoes, is spread on microscope slides and the films fixed by drying.
Delaunay A, J Lebrun, Mary Barber
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[19] Chemotactic factors of bacterial origin
1988Publisher Summary This chapter discusses the methodology that has been used to obtain partial or complete purification of bacterial peptide chemoattractants, including the chemoattractant fMet-Leu-Phe (fMLP) from E. coli culture filtrates. For the latter, definitive demonstration of the formylmethionyl group has been obtained following high ...
Wayne A. Marasco, Peter A. Ward
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Neutrophil chemotactic factors
1991Polymorphonuclear leukocytes (neutrophils) are recruited to inflammatory sites by a variety of soluble mediators (chemoattractants) that stimulate neutrophil directed migration (chemotaxis). Many neutrophil chemoattractants such as neutrophil activating proteins, leukotriene B4 (LTB4), platelet activating factor, and complement-derived C5a, are ...
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Immunoglobulin G as Possible Precursor of Chemotactic Factor [PDF]
Nature, 1970 FROM the site of an Arthus reaction or burn lesion, a chemical factor has been isolated (“leucoegressin”) that causes the accumulation of polymorphonuclear leucocytes1,2. A possible precursor has, moreover, been located in the γ2-globulin fraction of normal rabbit serum3, because when six protein fractions such as albumin and α1, α2, β1, β2 (or γ1) and
S. Yamamoto +3 more
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[12] Chemotactic factors: An overview
1988Publisher Summary The chemotactic factors of major interest are formyl peptides, C5a, and LTB 4 , the structure of each of which has been determined. The formyl peptides are the most widely used, because they have the advantage of being easy to synthesize in large quantity and have powerful and immediate actions on leukocytes, which can be assayed ...
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