Results 101 to 110 of about 65,117 (210)

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

A Review and Meta‐Analysis of Biomarkers in Early‐Stage Osteoarthritis

Orthopaedic Surgery, EarlyView.
A systematic review of biomarkers associated with osteoarthritis progression. Meta‐analysis of dysregulation among the biomarkers distinguishes it from baseline patients as well as other pathologies, suggesting advancements in early diagnosis of the disease.
Austin Lawrence, Joseph Boesel, Rogelio Martinez Aguilar, Drew Gryczewski, Ahmed Suparno Bahar Moni   +4 more
wiley   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Differences in the product characteristics and clinical use of granulocytes for transfusion: The BEST Collaborative study

Transfusion, EarlyView.
Abstract Background Whether granulocytes for transfusion are beneficial remains uncertain, although some evidence suggests that efficacy may be dose‐related. Granulocytes are mostly produced by apheresis procedure, but other means of production are increasingly used.
Lorna Cain, Charles Lafrance, Suzy Morton, Catherine Latour, Mélissa Girard, Pierre Tiberghien, Virginie de la Taille, Suvro Sankha Datta, Mrigender Singh Virk, Jennifer Andrews, Vered Yahalom, Ana María Pugliese, Romina Alba, Richard Charlewood, Susy Kirwan, Ana Paula Hitomi Yokoyama, Jose Mauro Kutner, Eva Alonso Nogues, Nuria Martinez i Llonch, James Daly, David O. Irving, Torsten J. Schulze, Elise Huisman, Kaatje Le Poole, Hans Vrielink, Nabiha H. Saifee, Monica B. Pagano, Simon Stanworth, The Biomedical Excellence for Safer Transfusion Collaborative   +28 more
wiley   +1 more source

Preinfection functions of blood polymorphonuclear leukocytes and the outcome of experimental escherichia-coli mastitis in the cow [PDF]

, 1990
A. Brand, A.S.J.P.A.M. Van Miert, Babior, Babior, C. Burvenich, Collins, Craven, Dulin, Frost, Henricks, Heyneman, Hill, Hill, J.A.C.M. Lohuis, J.H.M. Verheijden, Kehrli, Keller, Klesius, Lohuis, Nelson, P.A.J. Henricks, Paape, R. Heyneman, Roth, Van Der Vliet, Verhoef, Williams, Y.H. Schukken   +27 more
core   +1 more source

Environmental modulators of vascular physiology and inflammation

Experimental Physiology, EarlyView.
Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne, Anne Majumdar, Kalpana Surendranath, Mark R. Miller   +3 more
wiley   +1 more source

Specialized Pro‐Resolving Mediators as Emerging Players in Cardioprotection: From Inflammation Resolution to Therapeutic Potential

Acta Physiologica, Volume 241, Issue 7, July 2025.
ABSTRACT Aim Timely myocardial reperfusion is essential for restoring blood flow to post‐ischemic tissue, thereby reducing cardiac injury and limiting infarct size. However, this process can paradoxically result in additional, irreversible myocardial damage, known as myocardial ischemia–reperfusion injury (MIRI).
Anna De Bartolo, Naomi Romeo, Tommaso Angelone, Carmine Rocca   +3 more
wiley   +1 more source

P2Y14 receptor activation of platelets induces Ca2+ mobilization and Rho‐GTPase‐dependent motility that requires an interaction with P2Y1 receptors

British Journal of Pharmacology, Volume 182, Issue 13, Page 2950-2967, July 2025.
Background and Purpose Platelet function during inflammation is dependent on activation by endogenous nucleotides acting on purinergic receptors. The P2Y14 receptor has been reported to be expressed on platelets and is involved in leukocyte recruitment during inflammation.
Md Monir Hossain, Dingxin Pan, Kate L. Arkless, Khondaker Miraz Rahman, Clive P. Page, Kalwant S. Authi, Simon C. Pitchford   +6 more
wiley   +1 more source

Functional Interactions Between Recombinant Serum Amyloid A1 (SAA1) and Chemokines in Leukocyte Recruitment. [PDF]

Int J Mol Sci
Van Damme J, Struyf S, Proost P, Opdenakker G, Gouwy M.   +4 more
europepmc   +1 more source

Inflammation and response to bacterial infection as potential drivers of equine odontoclastic tooth resorption and hypercementosis: A proteomics insight

Equine Veterinary Journal, Volume 57, Issue 4, Page 977-990, July 2025.
Abstract Background Equine dental diseases significantly impact a horse's overall health, performance and quality of life. They can result in secondary infections and digestive disturbances, potentially leading to colic. A recently described disease affecting the incisors of horses is equine odontoclastic tooth resorption and hypercementosis (EOTRH ...
Anders Jensen, Emily J. Clarke, Zoe Nugent, Emily Paice, Iris Gringel, Kazuhiro Yamamoto, Guido Rocchigiani, Andrew J. Peffers, Lee Cooper, Mandy J. Peffers   +9 more
wiley   +1 more source