Results 11 to 20 of about 33,667 (226)

In vivo imaging and quantitative analysis of leukocyte directional migration and polarization in inflamed tissue [PDF]

, 2009
Directional migration of transmigrated leukocytes to the site of injury is a central event in the inflammatory response. Here, we present an in vivo chemotaxis assay enabling the visualization and quantitative analysis of subtype-specific directional ...
Alexander Georg Khandoga, Andrej Khandoga, B Heit, B Heit, C Auffray, C Sumen, C Weber, CA Reichel, Christoph Andreas Reichel, CX Sun, D Carstanjen, D Vestweber, DA Schuschke, F Wegmann, Fritz Krombach, G Bardi, G Migliorisi, Howard E. Gendelman, IG Colditz, J Alblas, J Middleton, J Werr, K Ley, K Ley, M Pruenster, Markus Rehberg, MD Cahalan, MJ Hickey, MJ Redd, MX Wan, O Soehnlein, P Friedl, Peter Bihari, RA Worthylake, RE Young, RJ Linhardt, RR Kay, S Baez, S Miyazaki, S Normark, S Nourshargh, SY Bae, T Lammermann, TA Russo, TR Mempel, V Niggli, WA Muller, WG Tharp   +47 more
core   +17 more sources

Monitoring Phosphoinositide Fluxes and Effectors During Leukocyte Chemotaxis and Phagocytosis

Frontiers in Cell and Developmental Biology, 2021
The dynamic re-organization of cellular membranes in response to extracellular stimuli is fundamental to the cell physiology of myeloid and lymphoid cells of the immune system.
Fernando Montaño-Rendón, Fernando Montaño-Rendón, Sergio Grinstein, Sergio Grinstein, Sergio Grinstein, Sergio Grinstein, Glenn F. W. Walpole, Glenn F. W. Walpole   +7 more
doaj   +1 more source

Identification and validation of candidate genes dysregulated in alveolar macrophages of acute respiratory distress syndrome [PDF]

PeerJ, 2021
Background Acute respiratory distress syndrome (ARDS) is a common cause of death in ICU patients and its underlying mechanism remains unclear, which leads to its high mortality rate. This study aimed to identify candidate genes potentially implicating in
Yong Mao, Xin Lv, Wei Xu, Youguo Ying, Zonghe Qin, Handi Liao, Li Chen, Ya Liu   +7 more
doaj   +2 more sources

Preinfection in vitro chemotaxis, phagocytosis, oxidative burst, and expression of CD11/CD18 receptors and their predictive capacity on the outcome of mastitis induced in dairy cows with Escherichia coli. [PDF]

, 1997
Four to 6 wk after parturition, 12 cows in second, fourth, or fifth lactation were experimentally infected in one gland with Escherichia coli. The capacity of chemotaxis, phagocytosis, oxidative burst, and expression of CD11/CD18 receptors to predict the
A. Brand, A.J.J.M. Daemen, Arfors, Burton, Burvenich, C. Burvenich, Cai, Caroll, Chenoweth, E.N. Noordhuizen-Stassen, Gelfand, Gilbert, Heyneman, Hill, Kehrli, Kehrli, Kremer, Lohuis, Myllys, Nagahata, Paape, Rainard, Saad, Schukken, Shuster, Simpson, Smith, Splitter, T. Van Werven, van Werven, Y.H. Schukken   +30 more
core   +2 more sources

Focal MMP-2 and MMP-9 Activity at the Blood-Brain Barrier Promotes Chemokine-Induced Leukocyte Migration

Cell Reports, 2015
Although chemokines are sufficient for chemotaxis of various cells, increasing evidence exists for their fine-tuning by selective proteolytic processing. Using a model of immune cell chemotaxis into the CNS (experimental autoimmune encephalomyelitis [EAE]
Jian Song, Chuan Wu, Eva Korpos, Xueli Zhang, Smriti M. Agrawal, Ying Wang, Cornelius Faber, Michael Schäfers, Heinrich Körner, Ghislain Opdenakker, Rupert Hallmann, Lydia Sorokin   +11 more
doaj   +1 more source

Psoriasis and Leukocyte Chemotaxis.

Journal of Investigative Dermatology, 1987
Transepidermal migration of leukocytes, with resultant formation of microscopic or macroscopic sterile subcorneal pustules is a phenomenon characteristically noted in psoriasis and related sterile pustular dermatoses. It is natural to assume the presence of potent neutrophil chemotactic substances in the subcorneal portion of the lesional epidermis ...
Hideaki Takematsu, Keiji Iwatsuki, Hachiro Tagami   +2 more
openaire   +3 more sources

Identification of an alternative G{alpha}q-dependent chemokine receptor signal transduction pathway in dendritic cells and granulocytes [PDF]

, 2007
CD38 controls the chemotaxis of leukocytes to some, but not all, chemokines, suggesting that chemokine receptor signaling in leukocytes is more diverse than previously appreciated.
Borchers, Michael T., Lee, James J., Lund, Frances E., Misra, Ravi S., Partida-Sánchz, Santiago, Shi, Guixiu, Simon, Melvin I., Tighe, Michael   +7 more
core   +2 more sources

Blood polymorphonuclear leukocyte chemotaxis during experimental escherichia-coli bovine mastitis. [PDF]

, 1993
The relationship between the severity of experimental Escherichia coli mastitis and the chemotactic response of blood polymorphonuclear leukocytes was investigated before and during mastitis. Experimental E.
A. Brand, A.J.J.M. Daemen, Brown, Burvenich, C. Burvenich, E.N. Noordhuizen-Stassen, Ellis, F.J. Grommers, Grommers, Heyneman, Hill, Hill, Jain, Jain, Kehrli, Kremer, Kremer, Lohuis, Löfstadt, Mowat, Nagahata, Nelson, Paape, Reid, W.D.J. Kremer   +24 more
core   +1 more source

Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF [PDF]

, 2002
Injury to peripheral nerves results in the infiltration of immune cells, which remove axonal- and myelin-derived material. Schwann cells could play a key role in this process by regulating macrophage infiltration.
Jessen, KR, Mirsky, R, Patterson, PH, Tofaris, GK   +3 more
core   +2 more sources

Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis [PDF]

, 2017
Background and Purpose: Inflammation plays a key role in atherosclerosis. A protective role of angiotensin-(1-7) in vascular pathologies opened a possibility for therapeutic use of small molecule non-peptide Ang-(1-7) mimetics, such as AVE0991.
Czesnikiewicz-Guzik, M., Guzik, T.J., Jawien, J., Korbut, R., Mikolajczyk, T.P., Montezano, A.C., Nosalski, R., Olszanecki, R., Rios, F.J., Siedlinski, M., Skiba, D.S., Touyz, R.M.   +11 more
core   +2 more sources