Results 21 to 30 of about 98,425 (307)

Combined boyden-flow cytometry assay improves quantification and provides phenotypification of leukocyte chemotaxis. [PDF]

PLoS ONE, 2011
Chemotaxis has been studied by classical methods that measure chemotactic and random motility responses in vitro, but these methods do not evaluate the total number and phenotype of migrating leukocytes simultaneously.
Nardhy Gomez-Lopez, Felipe Vadillo-Ortega, Guadalupe Estrada-Gutierrez   +2 more
doaj   +1 more source

Monitoring Phosphoinositide Fluxes and Effectors During Leukocyte Chemotaxis and Phagocytosis

Frontiers in Cell and Developmental Biology, 2021
The dynamic re-organization of cellular membranes in response to extracellular stimuli is fundamental to the cell physiology of myeloid and lymphoid cells of the immune system.
Fernando Montaño-Rendón, Fernando Montaño-Rendón, Sergio Grinstein, Sergio Grinstein, Sergio Grinstein, Sergio Grinstein, Glenn F. W. Walpole, Glenn F. W. Walpole   +7 more
doaj   +1 more source

A randomized double blinded placebo controlled clinical trial for the evaluation of green coffee extract on immune health in healthy adults

Journal of Traditional and Complementary Medicine, 2022
Background: The immune system functions to protect the host from a broad array of infectious diseases. Here, we evaluated the in vitro immunomodulatory effects of green coffee extract (GCE), and conducted a double-blinded, randomized and placebo ...
Jeyaparthasarathy Narayanaperumal, Avin D'souza, Amarnath Miriyala, Bhavna Sharma, Ganesh Gopal   +4 more
doaj   +1 more source

Focal MMP-2 and MMP-9 Activity at the Blood-Brain Barrier Promotes Chemokine-Induced Leukocyte Migration

Cell Reports, 2015
Although chemokines are sufficient for chemotaxis of various cells, increasing evidence exists for their fine-tuning by selective proteolytic processing. Using a model of immune cell chemotaxis into the CNS (experimental autoimmune encephalomyelitis [EAE]
Jian Song, Chuan Wu, Eva Korpos, Xueli Zhang, Smriti M. Agrawal, Ying Wang, Cornelius Faber, Michael Schäfers, Heinrich Körner, Ghislain Opdenakker, Rupert Hallmann, Lydia Sorokin   +11 more
doaj   +1 more source

Psoriasis and Leukocyte Chemotaxis.

Journal of Investigative Dermatology, 1987
Transepidermal migration of leukocytes, with resultant formation of microscopic or macroscopic sterile subcorneal pustules is a phenomenon characteristically noted in psoriasis and related sterile pustular dermatoses. It is natural to assume the presence of potent neutrophil chemotactic substances in the subcorneal portion of the lesional epidermis ...
Tagami, Hachiro, Iwatsuki, Keiji, Takematsu, Hideaki   +2 more
openaire   +2 more sources

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT, Bednar MM, Bellosta S, Buttrum SM, Buyon JP, Calara F, Calderon TM, Diacovo TG, Giroux LM, Jukema JW, Kim JA, Kimura M, Laufs U, Laws KH, Lehr H-A, Marcus AJ, Notabartolo A, Olstrowsky L, Pons F, Ruf A, Smalley DM, Stragliotto E, Sugiyama S, Weber C, Weber C, Weber C, Yeagle PL, Yeo EL, Yue TL   +28 more
core   +1 more source

CCR2 acts as scavenger for CCL2 during monocyte chemotaxis.

PLoS ONE, 2012
BackgroundLeukocyte migration is essential for effective host defense against invading pathogens and during immune homeostasis. A hallmark of the regulation of this process is the presentation of chemokines in gradients stimulating leukocyte chemotaxis ...
Silvia Volpe, Elisabetta Cameroni, Barbara Moepps, Sylvia Thelen, Tiziana Apuzzo, Marcus Thelen   +5 more
doaj   +1 more source

Skap2 is required for β2 integrin-mediated neutrophil recruitment and functions. [PDF]

, 2017
Integrin activation is required for neutrophil functions. Impaired integrin activation on neutrophils is the hallmark of leukocyte adhesion deficiency (LAD) syndrome in humans, characterized by impaired leukocyte recruitment and recurrent infections. The
Bardel, Bernadette, Block, Helena, Bokemeyer, Arne, Boras, Mark, Heitplatz, Barbara, Kliche, Stefanie, Lowell, Clifford, Reinhold, Annegret, Rossaint, Jan, Van Marck, Veerle, Volmering, Stephanie, Zarbock, Alexander   +11 more
core   +2 more sources

Identification and validation of candidate genes dysregulated in alveolar macrophages of acute respiratory distress syndrome [PDF]

PeerJ, 2021
Background Acute respiratory distress syndrome (ARDS) is a common cause of death in ICU patients and its underlying mechanism remains unclear, which leads to its high mortality rate. This study aimed to identify candidate genes potentially implicating in
Yong Mao, Xin Lv, Wei Xu, Youguo Ying, Zonghe Qin, Handi Liao, Li Chen, Ya Liu   +7 more
doaj   +2 more sources

Chemokines in the corpus luteum: Implications of leukocyte chemotaxis

Reproductive Biology and Endocrinology, 2003
Chemokines are small molecular weight peptides responsible for adhesion, activation, and recruitment of leukocytes into tissues. Leukocytes are thought to influence follicular atresia, ovulation, and luteal function.
Liptak Amy R, Townson David H
doaj   +1 more source