Results 31 to 40 of about 98,425 (307)

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo [PDF]

, 2013
Neutrophil recruitment from blood to extravascular sites of sterile or infectious tissue damage is a hallmark of early innate immune responses, and the molecular events leading to cell exit from the bloodstream have been well defined1,2. Once outside the
Afonso, P., Angermann, B., Germain, R., Kastenmüller, W., Lämmermann, T., Parent, C., Wang, J.   +6 more
core   +2 more sources

TLR signaling paralyzes monocyte chemotaxis through synergized effects of p38 MAPK and global Rap-1 activation. [PDF]

PLoS ONE, 2012
Toll-like receptors (TLRs) that recognize pathogen associated molecular patterns and chemoattractant receptors (CKRs) that orchestrate leukocyte migration to infected tissue are two arms of host innate immunity.
Ling Yi, Prabha Chandrasekaran, Sundararajan Venkatesan   +2 more
doaj   +1 more source

LEUKOCYTE LOCOMOTION AND CHEMOTAXIS [PDF]

The Journal of Experimental Medicine, 1973
Polymorphonuclear leukocyte (PMN) locomotion and chemotaxis have been evaluated by direct microscopic observation of individual cells in thin slide-cover slip preparations, and also by observations on populations of cells migrating into a Millipore filter.
Sally H. Zigmond, James G. Hirsch
openaire   +1 more source

A Functional Variant of CXCL16 Is Associated With Predisposition to Sepsis and MODS in Trauma Patients: Genetic Association Studies

Frontiers in Genetics, 2021
PurposeCXC chemokines are mediators which mediate immune cells migration to sites of inflammation and injury. Chemokine C-X-C motif ligand 16 (CXCL16) plays an important role in the occurrence and development of sepsis through leukocyte chemotaxis ...
Jianhui Sun, Huacai Zhang, Di Liu, Li Cui, Qiang Wang, Lebin Gan, Lebin Gan, Dalin Wen, Jun Wang, Juan Du, Hong Huang, Anqiang Zhang, Jin Deng, Jianxin Jiang, Ling Zeng   +14 more
doaj   +1 more source

Preinfection in vitro chemotaxis, phagocytosis, oxidative burst, and expression of CD11/CD18 receptors and their predictive capacity on the outcome of mastitis induced in dairy cows with Escherichia coli. [PDF]

, 1997
Four to 6 wk after parturition, 12 cows in second, fourth, or fifth lactation were experimentally infected in one gland with Escherichia coli. The capacity of chemotaxis, phagocytosis, oxidative burst, and expression of CD11/CD18 receptors to predict the
A. Brand, A.J.J.M. Daemen, Arfors, Burton, Burvenich, C. Burvenich, Cai, Caroll, Chenoweth, E.N. Noordhuizen-Stassen, Gelfand, Gilbert, Heyneman, Hill, Kehrli, Kehrli, Kremer, Lohuis, Myllys, Nagahata, Paape, Rainard, Saad, Schukken, Shuster, Simpson, Smith, Splitter, T. Van Werven, van Werven, Y.H. Schukken   +30 more
core   +2 more sources

"In vivo" leukocyte chemotaxis in experimental mice Schistosoma mansoni infection Quimiotaxia de leucócitos "in vivo" na infecção experimental por Schistosoma mansoni

Revista do Instituto de Medicina Tropical de São Paulo, 1994
The "in vivo" chemotaxis was studied in C57B1/10 mice 10, 30, 50 and 60 days after a Schistosoma mansoni infection in comparison to a control group (uninfected mice). Staphylococcal protein A was injected into a connective tissue air pouch of control and
Kirte Maria Teixeira, Amaury Domingues Coutinho, Silvia Maria Lucena Montenegro   +2 more
doaj   +1 more source

Targeting Chemokine—Glycosaminoglycan Interactions to Inhibit Inflammation

Frontiers in Immunology, 2020
Leukocyte migration into tissues depends on the activity of chemokines that form concentration gradients to guide leukocytes to a specific site. Interaction of chemokines with their specific G protein-coupled receptors (GPCRs) on leukocytes induces ...
Helena Crijns, Vincent Vanheule, Paul Proost   +2 more
doaj   +1 more source

Facilitated recruitment of mesenchymal stromal cells by bone marrow concentrate and platelet rich plasma. [PDF]

PLoS ONE, 2018
Biologics containing growth factors are frequently used to enhance healing after musculoskeletal injuries. One mechanism of action is thought to be though the ability of biologics to induce homing and migration of endogenous mesenchymal stromal cells ...
Hannah L Holmes, Brooke Wilson, Julian P Goerger, Jesse L Silverberg, Itai Cohen, Warren R Zipfel, Lisa A Fortier   +6 more
doaj   +1 more source

Evaluation of L-selectin expression and assessment of protein tyrosine phosphorylation in bovine polymorphonuclear neutrophil leukocytes around parturition. [PDF]

, 2002
Impaired polymorphonuclear neutrophil leukocyte (PMN) function around parturition has been associated with increased clinical mastitis in dairy cows. Rolling and attachment of PMN to the endothelium is the first step in the recruitment process and is ...
Burvenich, Christian, Capuco, Anthony, HUSHEEM, Michael, Monfardini, Erica, Paape, Max, WANG, Yan, WOOD, Larry   +6 more
core   +1 more source

Splenic Transcriptional Responses in Severe Visceral Leishmaniasis: Impaired Leukocyte Chemotaxis and Cell Cycle Arrest

Frontiers in Immunology, 2021
Structural changes in the spleen have been reported in several infectious diseases. In visceral leishmaniasis (VL), a severe parasitic disease caused by Leishmania spp., the loss of white pulp accompanies a severe clinical presentation.
Caroline Vilas Boas de Melo, Felipe Guimarães Torres, Micely D’El-Rei Hermida, Jonathan L. M. Fontes, Bianca Ramos Mesquita, Reginaldo Brito, Pablo Ivan P. Ramos, Gabriel R. Fernandes, Luiz Antônio Rodrigues Freitas, Ricardo Khouri, Carlos Henrique Nery Costa, Washington L. C. dos-Santos   +11 more
doaj   +1 more source