Results 11 to 20 of about 98,425 (307)
Metallothionein mediates leukocyte chemotaxis [PDF]
Background Metallothionein (MT) is a cysteine-rich, metal-binding protein that can be induced by a variety of agents. Modulation of MT levels has also been shown to alter specific immune functions.
Lynes Michael A +2 more
doaj +3 more sources
Potential molecular communication of blood and synovium through ligand-receptor interactions in osteoarthritis [PDF]
IntroductionOsteoarthritis (OA) is a common degenerative joint disease resulting from the breakdown of multiple joint tissues, remains a leading cause of disability with limited therapeutic options.
Maochun Wang +3 more
doaj +2 more sources
Signal-activated phospholipase regulation of leukocyte chemotaxis
Signal-activated phospholipases are a recent focus of the rapidly growing field of lipid signaling. The extent of their impact on the pathways regulating diverse cell functions is beginning to be appreciated.
Martha K. Cathcart
doaj +3 more sources
Combined Antiplatelet Therapy Reduces the Proinflammatory Properties of Activated Platelets
The cause of atherothrombosis is rupture or erosion of atherosclerotic lesions, leading to an increased risk of myocardial infarction or stroke. Here, platelet activation plays a major role, leading to the release of bioactive molecules, for example ...
Alexandra C.A. Heinzmann +4 more
doaj +1 more source
Here the authors use optogenetic tools to directly measure spatial signal processing in leukocyte chemotaxis. Their results reveal the importance of multiple negative feedback loops for maintaining spatial information in chemotaxis.
George R. R. Bell +3 more
doaj +1 more source
The aim of this study is to evaluate the phytochemical profile, oral acute toxicity, and the effect of ylang-ylang (Cananga odorata Hook. F. & Thomson) essential oil (YEO) on acute inflammation.
Robson Araújo de Freitas Junior +10 more
doaj +1 more source
Role of insulin hormone in modulation of inflammatory phenomena [PDF]
Evidence demonstrates the involvement of hormones in thedevelopment of inflammatory response. Inflammation evokes markedstructural alterations of microvasculature, besides migration ofleukocytes from microcirculation to the site of lesion.
Antonio Di Petta
doaj +4 more sources
Modeling leukocyte-leukocyte non-contact interactions in a lymph node. [PDF]
The interaction among leukocytes is at the basis of the innate and adaptive immune-response and it is largely ascribed to direct cell-cell contacts. However, the exchange of a number of chemical stimuli (chemokines) allows also non-contact interaction ...
Nicola Gritti +7 more
doaj +1 more source
An Agent-Based Interpretation of Leukocyte Chemotaxis in Cancer-on-Chip Experiments
The present paper was inspired by recent developments in laboratory experiments within the framework of cancer-on-chip technology, an immune-oncology microfluidic chip aiming at studying the fundamental mechanisms of immunocompetent behavior. We focus on
Gabriella Bretti, Andrea De Gaetano
doaj +1 more source
Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF [PDF]
Injury to peripheral nerves results in the infiltration of immune cells, which remove axonal- and myelin-derived material. Schwann cells could play a key role in this process by regulating macrophage infiltration.
Jessen, KR +3 more
core +2 more sources

