Results 11 to 20 of about 69,950 (300)

Metallothionein mediates leukocyte chemotaxis [PDF]

open access: yesBMC Immunology, 2005
Background Metallothionein (MT) is a cysteine-rich, metal-binding protein that can be induced by a variety of agents. Modulation of MT levels has also been shown to alter specific immune functions.
Lynes Michael A   +2 more
doaj   +4 more sources

Modeling leukocyte-leukocyte non-contact interactions in a lymph node. [PDF]

open access: yesPLoS ONE, 2013
The interaction among leukocytes is at the basis of the innate and adaptive immune-response and it is largely ascribed to direct cell-cell contacts. However, the exchange of a number of chemical stimuli (chemokines) allows also non-contact interaction ...
Nicola Gritti   +7 more
doaj   +2 more sources

Potential molecular communication of blood and synovium through ligand-receptor interactions in osteoarthritis [PDF]

open access: yesFrontiers in Medicine
IntroductionOsteoarthritis (OA) is a common degenerative joint disease resulting from the breakdown of multiple joint tissues, remains a leading cause of disability with limited therapeutic options.
Maochun Wang   +3 more
doaj   +2 more sources

Combined boyden-flow cytometry assay improves quantification and provides phenotypification of leukocyte chemotaxis. [PDF]

open access: yesPLoS ONE, 2011
Chemotaxis has been studied by classical methods that measure chemotactic and random motility responses in vitro, but these methods do not evaluate the total number and phenotype of migrating leukocytes simultaneously.
Nardhy Gomez-Lopez   +2 more
doaj   +3 more sources

THE EFFECT OF ANTIMICROBIAL AGENTS ON LEUKOCYTE CHEMOTAXIS

open access: yesJournal of Investigative Dermatology, 1978
The effects of several chemotherapeutic agents on the chemotaxis of human leukocytes were studied in an in vitro system using a Sykes-Moore chamber and a double-filter technique. Chemotactic factor was generated by the interaction of normal human serum and zymosan.
Esterly, Nancy B.   +2 more
openaire   +3 more sources

Splenic Transcriptional Responses in Severe Visceral Leishmaniasis: Impaired Leukocyte Chemotaxis and Cell Cycle Arrest [PDF]

open access: yesFrontiers in Immunology, 2021
Structural changes in the spleen have been reported in several infectious diseases. In visceral leishmaniasis (VL), a severe parasitic disease caused by Leishmania spp., the loss of white pulp accompanies a severe clinical presentation.
Caroline Vilas Boas de Melo   +11 more
doaj   +2 more sources

Combined Antiplatelet Therapy Reduces the Proinflammatory Properties of Activated Platelets

open access: yesTH Open, 2021
The cause of atherothrombosis is rupture or erosion of atherosclerotic lesions, leading to an increased risk of myocardial infarction or stroke. Here, platelet activation plays a major role, leading to the release of bioactive molecules, for example ...
Alexandra C.A. Heinzmann   +4 more
doaj   +1 more source

Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing

open access: yesNature Communications, 2021
Here the authors use optogenetic tools to directly measure spatial signal processing in leukocyte chemotaxis. Their results reveal the importance of multiple negative feedback loops for maintaining spatial information in chemotaxis.
George R. R. Bell   +3 more
doaj   +1 more source

Effect of Ylang-Ylang (Cananga odorata Hook. F. & Thomson) Essential Oil on Acute Inflammatory Response In Vitro and In Vivo

open access: yesMolecules, 2022
The aim of this study is to evaluate the phytochemical profile, oral acute toxicity, and the effect of ylang-ylang (Cananga odorata Hook. F. & Thomson) essential oil (YEO) on acute inflammation.
Robson Araújo de Freitas Junior   +10 more
doaj   +1 more source

Role of insulin hormone in modulation of inflammatory phenomena [PDF]

open access: yesEinstein (São Paulo), 2011
Evidence demonstrates the involvement of hormones in thedevelopment of inflammatory response. Inflammation evokes markedstructural alterations of microvasculature, besides migration ofleukocytes from microcirculation to the site of lesion.
Antonio Di Petta
doaj   +4 more sources

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