Results 201 to 210 of about 69,950 (300)

Heterogeneity and immune microenvironment of early invasive estrogen receptor-positive breast cancer reveal an immune-rich subset. [PDF]

NPJ Breast Cancer
Jain D, Liao L, Talebian V, Hopkins M, Quintayo MA, Crozier C, Bayani J, Cheung AM, Yaffe M, Bartlett J, Spears M.   +10 more
europepmc   +1 more source

SGO1 and SGO2 are Associated With Disease Progression and an Immunosuppressive Microenvironment in Papillary Renal Cell Carcinoma

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Shugoshin proteins SGO1 and SGO2 regulate chromosome cohesion and segregation during mitosis and meiosis, and their aberrant expression is implicated in several cancers. However, the mechanistic involvement of these two proteins in papillary renal cell carcinoma (KIRP) and their contribution to immune evasion remains unclear ...
Han Fu, Alisherjon Ibrohimov, Hao Zheng, Yue Pan, Jieyu Hu, Banzhan Ruan, Hang Huang, Shi Li   +7 more
wiley   +1 more source

Spatial and Functional Immune Profiling Identifies Impaired Vascular Repair in Human Myocardial Infarction. [PDF]

Biomedicines
Salybekov AA, Shaikalamova S, Kinzhebay A, Wolfien M, Asahara T.   +4 more
europepmc   +1 more source

Platelet extravasation in the microvasculature: an under-appreciated role for platelets. [PDF]

Front Immunol
Courson JA, Afshar-Kharghan V, Burns AR, Rumbaut RE.   +3 more
europepmc   +1 more source

Leukocyte locomotion and chemotaxis 1st International Conference on Leukocyte Locomotion and Chemotaxis, Gersau, May 16 - 21, 1982

, 1983
International Conference on Leukocyte Locomotion and Chemotaxis 1982 Gersau, Keller, Hansuli   +1 more
core  

First‐line envafolimab plus recombinant human‐endostatin in advanced non–small cell lung cancer with PD‐L1 tumor proportion score ≥1% (Endouble): A multicenter, prospective, single‐arm, phase 2 trial

Cancer, Volume 132, Issue 11, 1 June 2026.
Envafolimab combined with recombinant human endostatin demonstrates favorable efficacy and tolerable toxicity in non–small cell lung cancer patients. MMP1 and TNFRSF6B may be predictive biomarkers for treatment response. Abstract Background This trial evaluates the efficacy and safety of combining envafolimab and recombinant human endostatin (Rh ...
Changhong Dong, Liang Liu, Yun Qiao, Mei Wang, Daan Song, Lihua Zhou, Yajun Ji, Yan Li, Fendou Ding, Hao Wang, Min Zhuang, Lei Wang, Zhenghong Liu, Haitao Fei, Xiangjun Guo, Baoxiang Bian, Chunluan Yuan, Guanghui Xu, Lijian Fang, Yan Li, Ziyan Song, Kaiyuan Hui, Xiaodong Jiang   +22 more
wiley   +1 more source

Peripheral blood transcriptional profiling predicts tumor subtype and neoadjuvant chemoimmunotherapy outcomes in human breast cancer. [PDF]

Sci Transl Med
Sun X, Ocampo AA, Hanna A, Taylor BC, Marshall JL, Steele JA, Axelrod ML, Wescott EC, Opalenik SR, DeMichele A, Esserman LJ, Liu MC, Nanda R, Wolf DM, Brown Swigart L, Hirst GL, van 't Veer LJ, Xu Y, Balko JM.   +18 more
europepmc   +1 more source

Endothelial NEDD4L exacerbates acute lung injury by targeting A20 for ubiquitination degradation. [PDF]

Respir Res
Huan C, Jia F, Liu P, Xu Z, Shi Y.
europepmc   +1 more source

Leptin in Obesity‐Related Heart Failure: Pathophysiological Mechanisms and Therapeutic Implications

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Obesity‐associated adipose tissue dysfunction leads to hyperleptinemia and altered leptin signaling. Through Ob‐Rb/LepR‐mediated pathways, leptin may contribute to neurohormonal activation, endothelial dysfunction, inflammation, oxidative stress, and myocardial remodeling.
Xuemin Li, Weiguo Wang, Yibo Zhang, Pengfei Ding, Xuewen Li   +4 more
wiley   +1 more source

The dual non-competitive CXCR1/2 inhibitor ladarixin impairs neutrophil extravasation without altering intravascular adhesion. [PDF]

Haematologica
Napoli M, Sitaru S, Budke A, Kammerl A, Querner G, Immler R, Rohwedder I, Seifert S, Ferraro B, Weckbach L, Catz S, Aramini A, Amendola PG, Allegretti M, Bertini R, Pruenster M, Sperandio M.   +16 more
europepmc   +1 more source