Results 111 to 120 of about 277,006 (294)
Engineering Bacteria as Living Therapeutics in Cancer Therapy
Advanced Science, EarlyView.Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen +6 more
wiley +1 more source
Effect of Amino Acids and Oxygen on Chemotaxis in Escherichia coli
, 1966 Julius Adler
openalex +1 more source
Histamine-Induced Inhibition of Normal Human Basophil Chemotaxis to C5a [PDF]
, 1977 Michael A. Lett-Brown, Edward J. Leonard
openalex +1 more source
Targeting HDAC and PARP Enhances STING‐Dependent Antitumor Immunity in STING‐Deficient Tumor
Advanced Science, EarlyView.Dual HDAC and PARP inhibition restores STING signaling, enhances interferon response, and boosts antitumor immunity in STING‐deficient tumors. . Abstract The stimulator of interferon genes (STING)‐mediated innate immune pathway plays an important role in tumor immunosurveillance.
Chengzhou Mao +10 more
wiley +1 more source
Advanced Science, EarlyView.In this study, the expression and function of LCN2 in GC is aimed to investigate and elucidate the mechanisms by which the LCN2‐dependent positive‐feedback loop between GC cells and TAMs drives lymphangiogenesis and lymphatic metastasis. These findings suggest that LCN2 may serve as a potential prognostic biomarker and therapeutic target in GC ...
Zhixin Huang +15 more
wiley +1 more source
Influence of serum-derived chemotactic factors and bacterial products on human neutrophil chemotaxis [PDF]
, 1977 Andrew C. Issekutz, W. Douglas Biggar
openalex +1 more source
Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease
Advanced Science, EarlyView.Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou +18 more
wiley +1 more source
Tumor‐Tissue Boundaries as Instructive Interfaces in Breast Cancer Cell Invasion
Advanced Science, EarlyView.Tumor‐tissue boundaries reprogram metastatic breast cancer cells, enhancing invasiveness through an instructive, not permissive, mechanism. Using a 3D collagen I‐based tumor‐tissue interface model, single‐cell analysis, and simulations, this study shows that all cells can transmigrate without selective filtering, highlighting a targetable process in ...
Cornelia Clemens +6 more
wiley +1 more source
Decrease of the major high molecular weight surface glycoprotein of human granulocytes in monosomy-7 associated with defective chemotaxis [PDF]
, 1979 Carl G. Gahmberg +6 more
openalex +1 more source