Results 41 to 50 of about 277,155 (334)

TRPM2 ion channels steer neutrophils towards a source of hydrogen peroxide

open access: yesScientific Reports, 2021
Neutrophils must navigate accurately towards pathogens in order to destroy invaders and thus defend our bodies against infection. Here we show that hydrogen peroxide, a potent neutrophil chemoattractant, guides chemotaxis by activating calcium-permeable ...
Hassan Morad   +4 more
doaj   +1 more source

A corrected decoupled scheme for chemotaxis models [PDF]

open access: yesJ. Comput. Appl. Math. 323, 36--52 (2017), 2020
The main purpose of this paper is to present a new corrected decoupled scheme combined with a spatial finite volume method for chemotaxis models. First, we derive the scheme for a parabolic-elliptic chemotaxis model arising in embryology. We then establish the existence and uniqueness of the numerical solution, and we prove that it converges to a ...
arxiv   +1 more source

Chemotaxis as a navigation strategy to boost range expansion

open access: yesNature, 2019
Bacterial chemotaxis, the directed movement of cells along gradients of chemoattractants, is among the best-characterized subjects in molecular biology1–10, but much less is known about its physiological roles11.
J. Cremer   +5 more
semanticscholar   +1 more source

Drug targeting to decrease cardiotoxicity – determination of the cytotoxic effect of GnRH-based conjugates containing doxorubicin, daunorubicin and methotrexate on human cardiomyocytes and endothelial cells

open access: yesBeilstein Journal of Organic Chemistry, 2018
Background: Cardiomyopathy induced by the chemotherapeutic agents doxorubicin and daunorubicin is a major limiting factor for their application in cancer therapy.
Livia Polgár   +7 more
doaj   +1 more source

The Anaphase-Promoting Complex (APC) ubiquitin ligase affects chemosensory behavior in \u3cem\u3eC. elegans\u3c/em\u3e [PDF]

open access: yes, 2016
The regulation of fundamental aspects of neurobiological function has been linked to the ubiquitin signaling system (USS), which regulates the degradation and activity of proteins and is catalyzed by E1, E2, and E3 enzymes. The Anaphase-Promoting Complex
Jennings, Alexandra K.   +2 more
core   +3 more sources

Chemotactic network responses to live bacteria show independence of phagocytosis from chemoreceptor sensing

open access: yeseLife, 2017
Aspects of innate immunity derive from characteristics inherent to phagocytes, including chemotaxis toward and engulfment of unicellular organisms or cell debris.
Netra Pal Meena, Alan R Kimmel
doaj   +1 more source

The effect of bacterial chemotaxis on host infection and pathogenicity.

open access: yesFEMS Microbiology Reviews, 2018
Chemotaxis enables microorganisms to move according to chemical gradients. Although this process requires substantial cellular energy, it also affords key physiological benefits, including enhanced access to growth substrates.
Miguel A. Matilla, T. Krell
semanticscholar   +1 more source

Phoresis and Enhanced Diffusion Compete in Enzyme Chemotaxis. [PDF]

open access: yesNano letters (Print), 2018
Chemotaxis of enzymes in response to gradients in the concentration of their substrate has been widely reported in recent experiments, but a basic understanding of the process is still lacking. Here, we develop a microscopic theory for chemotaxis that is
J. Agudo-Canalejo   +2 more
semanticscholar   +1 more source

The Novel Protein Cj0371 Inhibits Chemotaxis of Campylobacter jejuni

open access: yesFrontiers in Microbiology, 2018
cj0371 is a novel gene that is associated with Campylobacter jejuni virulence, and an isogenic mutant of cj0371 showed hyper chemotaxis and motility. Chemotactic motility is an important virulence factor and is involved in C.
Xueqing Du   +5 more
doaj   +1 more source

Different migration patterns of sea urchin and mouse sperm revealed by a microfluidic chemotaxis device. [PDF]

open access: yesPLoS ONE, 2013
Chemotaxis refers to a process whereby cells move up or down a chemical gradient. Sperm chemotaxis is known to be a strategy exploited by marine invertebrates such as sea urchins to reach eggs efficiently in moving water.
Haixin Chang   +4 more
doaj   +1 more source

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