Results 71 to 80 of about 277,155 (334)

A novel computer vision‐based assessment of neutrophil chemotaxis in patients with severe infection

Clinical & Translational Immunology, 2021
Objectives To evaluate the value of chemotactic function of neutrophils in patients with severe infections. Methods A computer vision‐based cellular chemotaxis analysis platform was established for the dynamic assessment of neutrophil chemotaxis.
Yunxi Yang, Lu Liu, Zaiwen Guo, Jiamin Huang, Linbin Li, Yiming Shao, Mingming Song, Aixiang Yang, Bingwei Sun   +8 more
doaj   +1 more source

Identification of Positive Chemotaxis in the Protozoan Pathogen Trypanosoma brucei

mSphere, 2020
To complete its infectious cycle, the protozoan parasite Trypanosoma brucei must navigate through diverse tissue environments in both its tsetse fly and mammalian hosts. This is hypothesized to be driven by yet unidentified chemotactic cues.
Stephanie F. DeMarco, Edwin A. Saada, Miguel A. Lopez, Kent L. Hill   +3 more
doaj   +3 more sources

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Impaired neutrophil directional chemotactic accuracy in chronic periodontitis patients [PDF]

, 2015
Aim: To investigate the chemotactic accuracy of peripheral blood neutrophils from patients with chronic periodontitis compared with matched healthy controls, before and after non-surgical periodontal therapy.
Agarwal, Andrew, Bagorda, Berridge, Biemond, Bostan, Brock, Cedergren, Champagne, Chapple, Chapple, Chapple, Choi, Clark, Cooper, Cotter, Daniel, Dias, Dias, Dias, Dickinson, Dietrich, Dyke, Dyke, Dyke, Dyke, Dyke, Fu, Fujita, Gamonal, Graves, Grossi, Haastert, Harvath, Henry, Herlihy, Herlihy, Kantarci, Kaul, Kolaczkowska, Kuiper, Kumar, Kurihara, Lakshman, Lambeth, Lavine, Matthews, Matthews, Miesel, Mizuno, Muinonen-Martin, Nibali, Niethammer, Nishizuka, Offenbacher, Pablo, Page, Partida-Sanchez, Phillips, Rahman, Sackmann, Samanta, Sapey, Toker, Tsai, Tyagi, Van Dyke, Wells, Worthen, Wright, Yagi, Yoshikawa, Zigmond   +72 more
core   +2 more sources

An Updated Perspective on Sinorhizobium meliloti Chemotaxis to Alfalfa Flavonoids

Frontiers in Microbiology, 2020
The symbiotic interaction between leguminous plants and their cognate rhizobia allows for the fixation of gaseous dinitrogen into bioavailable ammonia.
K. Karl Compton, Sherry B. Hildreth, Richard F. Helm, Birgit E. Scharf   +3 more
doaj   +1 more source

Negligibility of haptotaxis effect in a chemotaxis-haptotaxis model [PDF]

arXiv, 2020
In this work, we rigorously study chemotaxis effect versus haptotaxis effect on boundedness, blow-up and asymptotical behavior of solutions for a combined chemotaxis-haptotaxis model in 2D settings. It is well-known that the corresponding Keller-Segel chemotaxis-only model possesses a striking feature of critical mass blow-up phenomenon, namely ...
arxiv  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Chemotaxis towards autoinducer 2 mediates autoaggregation in Escherichia coli

Nature Communications, 2016
Bacteria communicate by producing and sensing extracellular signal molecules called autoinducers. Such intercellular signalling, known as quorum sensing, allows bacteria to coordinate and synchronize behavioural responses at high cell densities ...
Leanid Laganenka, R. Colin, V. Sourjik
semanticscholar   +1 more source

Self-similar dynamics of bacterial chemotaxis

, 2012
Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical concentration ...
J. Murray, Kannika Khompurngson, T. Matsuyama, Waipot Ngamsaad   +3 more
core   +1 more source

A Novel Microfluidic Device for the Neutrophil Functional Phenotype Analysis: Effects of Glucose and Its Derivatives AGEs

Micromachines, 2021
Neutrophil dysfunction is closely related to the pathophysiology of patients with diabetes mellitus, but existing immunoassays are difficult to implement in clinical applications, and neutrophil’s chemotaxis as a functional biomarker for diabetes ...
Ke Yang, Xiao Yang, Chaoru Gao, Changyi Hua, Chenggang Hong, Ling Zhu   +5 more
doaj   +1 more source