Results 71 to 80 of about 60,074 (286)

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Omission of dexamethasone in prophylaxis for highly emetogenic chemotherapy in patients with breast cancer [PDF]

Einstein (São Paulo)
Objective Chemotherapy-induced nausea and vomiting are highly prevalent adverse events that can lead to poor treatment adherence and a decreased quality of life.
Camilla Vieira de Rebouças, Rafaela de Brito Alves, Alayne Magalhães Trindade Domingues Yamada, Auro del Giglio, Felipe José Silva Melo Cruz   +4 more
doaj   +1 more source

A scoping review of nausea, vomiting and retching measurement methods in children with cancer

Pediatrics and Neonatology, 2022
Evaluation of chemotherapy-induced nausea and vomiting (CINV) in the pediatric population is subject to diverse approaches. This scoping review summarizes the methods used in clinical studies that assessed nausea, vomiting or retching in children with ...
Celeste LY. Ewig, Wai Yin Yung, Hobart Ho Man Ng, Cho Lee Wong, Alex Wing Kwan Leung, Chi-kong Li, Yin Ting Cheung   +6 more
doaj   +1 more source

Acupressure on Zusanli (St36) and Taibai (Sp3) in Reducing Nausea for Patients with Dyspepsia at Banyumas Hospital [PDF]

, 2014
Background: Nausea is unpleasant sensation behind the throat and epigastrium often causing vomiting. Nausea is a major symptom in patients with dyspepsia. Typical treatments for nausea are antiemetic drugs and non-pharmacological therapy.
Achiriyati, D. (Deny), Mardiyono, M. (Mardiyono), Oktaviani, R. (Rizky)   +2 more
core  

Antiemetic research: future directions [PDF]

, 2010
PURPOSE AND METHODS: As a part of reviewing the Multinational Association of Supportive Care in Cancer (MASCC) antiemetic guidelines in Perugia in 2009, an expert group identified directions for future antiemetic research.
Aapro, Matti, Grunberg, Steven, Herrstedt, Jørn, Molassiotis, Alexander, Morrow, Garry, Olver, Ian   +5 more
core   +1 more source

Impacts of Diets and Food Plans in Health and Diseases—A Narrative Review

Food Safety and Health, EarlyView.
This review emphasizes different diet types, providing insights into their nutritional content and health effects. Vegetarian and vegan diets, ketogenic diets, Mediterranean diets, Western diets, pescatarian diets, flexitarian diets, and territorial diversified diets are discussed, highlighting their influences on health, and diseases.
Md. Mahbubar Rahman, Manisha Pandit, Bhawana Thukral, Morshed M. Khandoker   +3 more
wiley   +1 more source

Using haloperidol as an anti-emetic in palliative care: informing practice through evidence from cancer treatment and post-operative contexts [PDF]

, 2013
YesNausea and vomiting are common symptoms in palliative care. Haloperidol is often used as an antiemetic in this context, although direct evidence supporting this practice is limited.
Alison Blenkinsopp, Büttner M, Chaparro LE, Chu CC, Cole DR, Critchley P, Depoortère R, Feng PH, Glare P, Grecu L, Hardy JR, Hsu WH, Janssen PAJ, Jha SK, Keeley PW, Kennett A, Lee Y, Lima L, Michael I. Bennett, Neidhart JA, Osinski MA, Perkins P, Rosow CE, Sadashivaiah R, Samantha L. McLean, Settle EC, Tramèr MR, Wang TF   +27 more
core   +1 more source

Hypofractionated Spot Scanning Proton Therapy for Head and Neck Mucosal Melanoma: A Retrospective Analysis With Quality‐of‐Life Outcome

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate clinical outcomes and quality of life (QOL) following hypofractionated spot‐scanning proton therapy (SSPT) for head and neck malignant mucosal melanoma (HNMM). Methods This retrospective study included 39 patients treated with SSPT (60–64 Gy[RBE] in 15–16 fractions) between 2013 and 2023.
Koichiro Nakajima, Hiromitsu Iwata, Gaku Takano, Daiki Kojima, Yukiko Hattori, Yusuke Tsuzuki, Shuou Sudo, Kensuke Hayashi, Toshiyuki Toshito, Hideo Fukano, Hiroyuki Ogino, Akio Hiwatashi   +11 more
wiley   +1 more source

PARP inhibition: a promising therapeutic target in ovarian cancer [PDF]

, 2015
Ovarian cancer is burdened by the highest mortality rate among gynecological cancers. Gold standard is represented by the association of platinum-taxane -based chemotherapy and radical surgery.
Abdul Halim, T, BENEDETTI PANICI, PIERLUIGI, CASORELLI, ASSUNTA, DI DONATO, VIOLANTE, DOMENICI, LAVINIA, GASPARRI, MARIALUISA, IMPERIALE, LUDOVICA, MARCHETTI, CLAUDIA, MONTI, Marco, MUSELLA, ANGELA, MUZII, LUDOVICO, PALAIA, INNOCENZA, PECORINI, Francesco, RUSCITO, ILARY, SALERNO, LAURA   +14 more
core   +1 more source

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

International Journal of Cancer, EarlyView.
What's New? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma, Kai Ou, Xiu Liu, Biyang Cao, Wenwei Yang, Jingyu Lu, Letian Zhang, Qi Wang, Lizhen Gao, Zhichao Jiang, Yongkun Sun, Lin Yang   +11 more
wiley   +1 more source