Results 61 to 70 of about 1,969,863 (367)

Impact of chemotherapy-induced nausea and vomiting on quality of life in indonesian patients with gynecologic cancer. [PDF]

, 2011
Patients reported a negative impact on the QoL of delayed emesis after chemotherapy. Poor prophylaxis of patients' nausea and vomiting after chemotherapy interferes with patients' QoL.
Atthobari, Jarir, Dwiprahasto, Iwan, Gelderblom, Hans, Guchelaar, Henk-Jan, Hakimi, Mohammad, Kaptein, Ad A, Mustofa, Mustofa, Nortier, Johan W R, Perwitasari, Dyah Aryani, Putter, Hein   +9 more
core   +1 more source

Antiviral chemotherapy [PDF]

Infection, 1984
After a discussion of the principles of antiviral chemotherapy, treatment and chemoprophylaxis of the following virus infections are reviewed in detail: the various manifestations of herpes simplex virus infections, varicella-zoster, cytomegalovirus infections, Epstein-Barr virus infections, laryngeal papillomas, and influenza A.
openaire   +3 more sources

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Antimicrobial resistance of nosocomial Staphylococcus aureus isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
The study included 418 of the 841 clinical isolates of S. aureus, which were regarded as nosocomial. These 418 clinical nosocomial S. aureus strains were isolated in 2013-2014 from patients hospitalized in 25 hospitals in 19 Russian cities.
Romanov A.V., Dekhnich A.V., Sukhorukova M.V., Skleenova E.Yu., Ivanchik N.V., Edelstein M.V., Kozlov R.S., «MARATHON» Study Group   +7 more
doaj  

Role of endogenous and exogenous antioxidants in risk of six cancers: evidence from the Mendelian randomization study

Frontiers in Pharmacology, 2023
Background: Although oxidative stress is known to contribute to cancer, and endogenous and exogenous antioxidants are thought to prevent tumorigenesis by suppressing oxidative stress-induced DNA damage, antioxidants have also been reported to show ...
Jiahao Zhu, Jie Lian, Xin Wang, Ren Wang, Xiangyi Pang, Benjie Xu, Xing Wang, Chenyang Li, Shengjun Ji, Haibo Lu   +9 more
doaj   +1 more source

Controlled Comparison of Oral Twice-weekly and Oral Daily Isoniazid plus PAS in Newly Diagnosed Pulmonary Tuberculosis [PDF]

, 1973
A controlled clinical trial was undertaken in 247 patients with newly diagnosed pulmonary tuberculosis to assess the relative efficacies of a fully supervised twice-weekly oral regimen of isoniazid plus PAS (para-aminosalicylic acid) and a standard ...
Tuberculosis Chemotherapy Centre, Madras
core  

Outcome of ATP-based tumor chemosensitivity assay directed chemotherapy in heavily pre-treated recurrent ovarian carcinoma [PDF]

, 2003
BACKGROUND: We wished to evaluate the clinical response following ATP-Tumor Chemosensitivity Assay (ATP-TCA) directed salvage chemotherapy in a series of UK patients with advanced ovarian cancer. The results are compared with that of a similar assay used
A du Bois, A Villa, Alan Lamont, AN Gordon, Andrew C Hindley, B Lund, Bernard R Higgins, Christian M Kurbacher, CM Kurbacher, CM Kurbacher, DD Von Hoff, DD Von Hoff, DL Clarke-Pearson, DS Ettinger, EM Hunter, Federica Di Nicolantonio, G Blackledge, G Konecny, GJ Rustin, GJ Rustin, IA Cree, IA Cree, IA Cree, Ian A Cree, J Kaern, JS Berek, JT Thigpen, KA Donovan, Louise A Knight, M Breidenbach, M Breidenbach, M Gore, M Harries, M Markman, M Markman, M Markman, M Markman, Martin Gore, ME Gore, ME Gore, ME van der Burg, MH Neale, Michael H Neale, MJ Piccart, ML Hensley, N Myatt, OM Grecu, P Hanjani, P Therasse, Pauline A Whitehouse, PE Andreotti, PG Rose, RD Petty, Richard Osborne, Robert T. Greenlee, Sanjay Sharma, Stuart J Mercer, T Meyer, U Kurbacher CM Stier, WP McGuire   +59 more
core   +4 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Spautin-1 inhibits mitochondrial complex I and leads to suppression of the unfolded protein response and cell survival during glucose starvation

Scientific Reports, 2022
The unfolded protein response (UPR) is an adaptive stress response pathway that is essential for cancer cell survival under endoplasmic reticulum stress such as during glucose starvation.
Kazuhiro Kunimasa, Chika Ikeda-Ishikawa, Yuri Tani, Satomi Tsukahara, Junko Sakurai, Yuka Okamoto, Masaru Koido, Shingo Dan, Akihiro Tomida   +8 more
doaj   +1 more source

Optimal chemotherapy and immunotherapy schedules for a cancer-obesity model with Caputo time fractional derivative [PDF]

, 2018
This work presents a new mathematical model to depict the effect of obesity on cancerous tumor growth when chemotherapy as well as immunotherapy have been administered. We consider an optimal control problem to destroy the tumor population and minimize the drug dose over a finite time interval.
arxiv   +1 more source