Results 81 to 90 of about 5,134,427 (306)

Ursodeoxycholic acid treatment in cholesterol gallstone disease: effects on hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity, biliary lipid composition, and plasma lipid levels

Journal of Lipid Research, 1983
The present study was undertaken to characterize the effects of ursodeoxycholic acid on biliary lipid metabolism in man. Fifteen gallstone patients were treated with ursodeoxycholic acid at a daily dosage of 15 mg per kg body weight for about 4 weeks ...
B Angelin, S Ewerth, K Einarsson
doaj   +1 more source

Improved performance of porphyrin-based dye sensitised solar cells by phosphinic acid surface treatment [PDF]

, 2009
Chemical surface treatment of porphyrin-sensitised titania films using bis-(4-methoxyphenyl) phosphinic acid after dye adsorption, results in large improvements in DSSC efficiencies which originate primarily from higher short circuit currents. The result
Alessandra Allegrucci, Attila J. Mozer, Campbell, David L. Officer, Durrant, Fabregat-Santiago, Forneli, Frank, Guerrero, Haque, Haque, Kanzaki, Katoh, Kenji Sunahara, Koumura, Kuang, Kuciauskas, Lee, Leone Spiccia, Lynn Dennany, Miyashita, Mozer, Nakade, Nakade, Naomi A. Lewcenko, Neale, O'Regan, Paulsson, Pawel Wagner, Shogo Mori, Wang, Wang, Wang, Wang, Watson, Yum   +35 more
core   +2 more sources

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi   +8 more
wiley   +1 more source

7 beta-Dehydroxylation of ursodeoxycholic acid by whole cells and cell extracts of the intestinal anaerobic bacterium, Eubacterium species V.P.I. 12708.

Journal of Lipid Research, 1982
Whole cells and cell extracts of Eubacterium species V. P. I. 12708 7-dehydroxylated [3H]ursodeoxycholic acid or [14C]chenodeoxycholic forming lithocholic acid.
B A White, R J Fricke, P B Hylemon
doaj   +1 more source

Ruminal methane inhibition potential of various pure compounds in comparison with garlic oil as determined with a rumen simulation technique (Rusitec) [PDF]

, 2017
Ruminants represent an important source of methane (CH4) emissions; therefore, CH4 mitigation by diet supplementation is a major goal in the current ruminant research. The objective of the present study was to use a rumen simulation technique to evaluate
Amelchanka, Sergej L., Duval, Stéphane M., Kreuzer, Michael, Soliva, Carla R.   +3 more
core  

Improving the Performance and High‐Field Stability of FAPbBr₃ Single Crystals in X‐Ray Detection with Chenodeoxycholic Acid Additive [PDF]

, 2023
Wei Jiang, Jiwei Ren, Haibin Li, Dan Liŭ, Lijun Yang, Ying Xiong, Yiying Zhao   +6 more
openalex   +1 more source

Bile Acids as Key Mediators of the Gut Microbiota–Immune Axis: Potential Biomarker and Therapeutic Perspectives

BioFactors, Volume 52, Issue 1, January/February 2026.
Primary bile acids synthesized in the liver are transformed by gut microbes into secondary bile acids that engage receptors such as FXR and TGR5, thereby modulating immune function and metabolic homeostasis. Dysregulation of these signaling pathways contributes to MASH, NAFLD, IBD, and neurodegenerative disorders, underscoring their relevance as ...
Simone Baldi, Margherita Turrini, Francesco Cei, Marta Menicatti, Gianluca Bartolucci, Amedeo Amedei   +5 more
wiley   +1 more source

TGR 5 signalling inhibits the production of pro‐inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease [PDF]

, 2013
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97471/1/imm12045 ...
Hibi, Toshifumi, Hisamatsu, Tadakazu, Ichikawa, Riko, Kamada, Nobuhiko, Kanai, Takanori, Kitazume, Mina T., Koganei, Kazutaka, Matsuoka, Katsuyoshi, Mori, Maiko, Namikawa, Yuka, Sato, Toshiro, Shimamura, Katsuyoshi, Sugita, Akira, Uo, Michihide, Yoneno, Kazuaki   +14 more
core   +1 more source

Inflammatory bowel disease and metabolic reprogramming: From pathological mechanisms to targeted interventions

Interdisciplinary Medicine, Volume 4, Issue 1, January 2026.
This review explores the role of metabolic reprogramming in inflammatory bowel disease (IBD) by focusing on immune and epithelial cell metabolism, microbial metabolites, and their impact on inflammation. It discusses emerging metabolic therapies and emphasizes the importance of personalized microbiota‐targeted approaches to improve clinical outcomes in
Zemin Tian, Yinde Huang, Ying Wang, Chenyu Zhao, Zhaokai Zhou, Hua Yang, Yuan Qiu   +6 more
wiley   +1 more source

Synthesis of new bile salt analogues, sodium 3 alpha, 7 alpha-dihydroxy-5 beta-cholane-24-sulfonate and sodium 3 alpha, 7 beta-dihydroxy-5 beta-cholane-24-sulfonate.

Journal of Lipid Research, 1990
This report describes the chemical synthesis of two new bile salt analogues, namely sodium 3 alpha,7 alpha-dihydroxy-5 beta-cholane-24-sulfonate and sodium 3 alpha,7 beta-dihydroxy-5 beta-cholane-24-sulfonate from chenodeoxycholic acid and ...
K Kihira, M Yoshii, A Okamoto, S Ikawa, H Ishii, T Hoshita   +5 more
doaj   +1 more source