Results 81 to 90 of about 16,871 (260)

Beyond weight loss: exploring bile acid modulations after bariatric surgery and their impact on type 2 diabetes across 5 years

Obesity, Volume 33, Issue 7, Page 1275-1286, July 2025.
Abstract Objective This study aimed to explore the dynamic role of bile acids (BAs) in metabolic improvements following bariatric surgery, specifically comparing the effects of silastic ring laparoscopic Roux‐en‐Y gastric bypass (SR‐LRYGB) and laparoscopic sleeve gastrectomy (LSG) on BA composition and clinical parameters over a 5‐year period.
John Zhiyong Yang, Michelle Li, Weiyu Zhou, Reza Nemati, Xiaodong Jin, Lindsay D. Plank, Rinki Murphy, Jun Lu   +7 more
wiley   +1 more source

Human hepatoblastoma cells (HepG2) and rat hepatoma cells are defective in important enzyme activities in the oxidation of the C27 steroid side chain in bile acid formation

Journal of Lipid Research, 1993
We have examined the ability of HepG2 human hepatoblastoma cells and 7800 C1 Morris rat hepatoma cells to convert 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoic acid (THCA) and 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic acid (DHCA) to ...
Ann-Kristin Östlund Farrants, Astrid Nilsson, Jan I. Pedersen   +2 more
doaj  

HFD Exacerbates Hepatic Lipid Metabolism Disorders After Cholecystectomy by Regulating the Bile Acid and Neutrophil Recruitment

Liver International, Volume 45, Issue 7, July 2025.
ABSTRACT Background and Aims Previous studies have suggested that cholecystectomy may lead to an elevated risk of metabolic dysfunction‐associated fatty liver disease (MAFLD). However, there is a dearth of knowledge concerning the precise effects and underlying mechanisms through which cholecystectomy influences hepatic lipid metabolism, necessitating ...
Yanting Xu, Feng Zhang, Ziliang Ke, Yiken Lin, Yang Zhang, Yun Liu, Yifan Zhang, Jun Xu, Yulan Liu   +8 more
wiley   +1 more source

Cofactor requiremets for 7 alpha-dehydroxylation of cholic and chenodeoxycholic acid in cell extracts of the intestinal anaerobic bacterium, Eubacterium species V.P.I. 13708.

Journal of Lipid Research, 1981
The characteristics of 7 alpha-dehydroxylase, a bile acid-biotransforming enzyme, were determined using dialyzed cell extracts of Eubacterium sp. V.P.I. 12708. 7 alpha-Dehydroxylase was induced by cholic acid in this organism.
B A White, A F Cacciapuoti, R J Fricke, T R Whitehead, E H Mosbach, P B Hylemon   +5 more
doaj  

Cholesterol reducing and bile-acid binding properties of taioba (Xanthosoma sagittifolium) leaf in rats fed a high-fat diet [PDF]

, 2013
The consumption of vegetables has been correlated with reduced risk of chronic non-communicable diseases due to the high fiber content and bioactive compounds found in vegetables.
Amaya-Farfán, Jaime, de Almeida Jackix, Elisa, Monteiro, Elisa Bernardes, Raposo, Helena Fonseca   +3 more
core   +1 more source

Occurrence and Metabolism of Chenodeoxycholic Acid in the Rat. Bile Acids and Steroids. 13. [PDF]

, 1954
Sune Bergström, Jan Sjövall, Roger Bonnichsen, John Rastrup Andersen   +3 more
openalex   +1 more source

Bile acids of marsupials. 2. Hepatic formation of vulpecholic acid (1 alpha,3 alpha,7 alpha-trihydroxy-5 beta-cholan-24-oic acid) from chenodeoxycholic acid in a marsupial, Trichosurus vulpecula (Lesson).

Journal of Lipid Research, 1991
Free vulpecholic acid (1 alpha,3 alpha,7 alpha-trihydroxy-5 beta-cholan-24-oic) is the major biliary component of the Australian opossum (Trichosurus vulpecula), accompanied only by a few percent of its taurine conjugate.
J St Pyrek, SP Lee, L Thomsen, C Tasman-Jones, B Leydon   +4 more
doaj  

A Method for Spectrophotometric Determination of Chenodeoxycholic Acid in Bile. [PDF]

, 1954
Björn Isaksson, L. Ƶechmeister, Børge Bak, John Rastrup Andersen   +3 more
openalex   +1 more source

TGR 5 signalling inhibits the production of pro‐inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease [PDF]

, 2013
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97471/1/imm12045 ...
Hibi, Toshifumi, Hisamatsu, Tadakazu, Ichikawa, Riko, Kamada, Nobuhiko, Kanai, Takanori, Kitazume, Mina T., Koganei, Kazutaka, Matsuoka, Katsuyoshi, Mori, Maiko, Namikawa, Yuka, Sato, Toshiro, Shimamura, Katsuyoshi, Sugita, Akira, Uo, Michihide, Yoneno, Kazuaki   +14 more
core   +1 more source

Effect of ethanol on cholesterol and bile acid metabolism

Journal of Lipid Research, 1972
Ethanol feeding increased significantly levels of hepatic esterified cholesterol and serum free and esterified cholesterol in rats. Incorporation of intraperitoneally administered [14C]acetate into cholesterol was significantly increased.
A.F. Lefèvre, L.M. DeCarli, C.S. Lieber
doaj