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Genomic surveillance of the Chikungunya Virus (CHIKV) in Northeast Brazil after the first outbreak in 2014. [PDF]

open access: diamondRev Soc Bras Med Trop, 2020
We performed an epidemiological surveillance of the Chikungunya (CHIKV) lineages in Bahia after the 2014 East/Central/South African (ECSA) genotype outbreak.Reverse-transcription polymerase chain reaction (RT-PCR), viral isolation, and phylogenetic analyses were conducted on serum samples from 605 patients with CHIKV-like symptoms during 2014-2018.Of ...
Rodrigues AM   +6 more
europepmc   +6 more sources

Infectious Chikungunya Virus (CHIKV) with a Complete Capsid Deletion: a New Approach for a CHIKV Vaccine. [PDF]

open access: bronzeJ Virol, 2019
Currently, there is no licensed vaccine against CHIKV infection. An ideal CHIKV vaccine should generate an optimal balance between efficacy and safety. Live attenuated vaccines that can elicit strong immune responses often involve a trade-off of reduced safety. Here, a novel live attenuated vaccine candidate for CHIKV lacking the entire capsid gene, ΔC-
Zhang YN   +7 more
europepmc   +6 more sources

Isolation and diagnosis of Chikungunya virus causing outbreaks in Andhra Pradesh, India [PDF]

open access: yesJournal of Clinical and Scientific Research, 2013
Background: Chikungunya fever has recently re-emerged in India with a high morbidity. However, the prevalence of chikungunya fever in India has been underreported due to non-availability of specialized kits to confirm the disease in most of the ...
C.V.M. Naresh Kumar, D.V.R. Sai Gopa
doaj   +2 more sources

2888. Safety and Immunogenicity of an Adjuvanted Chikungunya Virus (CHIKV) Virus-like Particle (VLP) Based Vaccine in Two Pivotal Phase 3 Trials, ≥12 Years of Age [PDF]

open access: goldOpen Forum Infect Dis, 2023
Jason S. Richardson   +9 more
europepmc   +3 more sources

A retrospective investigation for the seroprevalence of Chikungunya virus and its co-existence with Dengue virus in Pakistani population, 2014–2015 [PDF]

open access: yesScientific Reports
Dengue and Chikungunya are caused by the same vectors, Aedes aegypti and Aedes albopictus. Both mosquitoes are endemic in Pakistan, and various parts of the country experienced outbreaks of Dengue virus over the past decades.
Darakhshan Guhar   +4 more
doaj   +2 more sources

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