Results 1 to 10 of about 26,631 (250)

Infectious Chikungunya Virus (CHIKV) with a Complete Capsid Deletion: a New Approach for a CHIKV Vaccine. [PDF]

J Virol, 2019
Currently, there is no licensed vaccine against CHIKV infection. An ideal CHIKV vaccine should generate an optimal balance between efficacy and safety. Live attenuated vaccines that can elicit strong immune responses often involve a trade-off of reduced ...
Zhang YN, Deng CL, Li JQ, Li N, Zhang QY, Ye HQ, Yuan ZM, Zhang B.   +7 more
europepmc   +5 more sources

Large-scale outbreak of Chikungunya virus infection in Thailand, 2018-2019.

PLoS ONE, 2021
Between 2018 and 2019, the incidence of chikungunya was approximately 15,000 cases across 60 provinces in Thailand. Here, the clinical presentations in chikungunya, emergent pattern, and genomic diversity of the chikungunya virus (CHIKV) causing this ...
Sarawut Khongwichit, Jira Chansaenroj, Thanunrat Thongmee, Saovanee Benjamanukul, Nasamon Wanlapakorn, Chintana Chirathaworn, Yong Poovorawan   +6 more
doaj   +2 more sources

Chikungunya Virus: Priority Pathogen or Passing Trend?

Vaccines, 2023
Chikungunya virus (CHIKV) is considered a priority pathogen and a major threat to global health. While CHIKV infections may be asymptomatic, symptomatic patients can develop chikungunya fever (CHIKF) characterized by severe arthralgia which often ...
Gerardo Montalvo Zurbia-Flores, Arturo Reyes-Sandoval, Young Chan Kim   +2 more
doaj   +2 more sources

Dengue, chikungunya and Zika virus surveillance in blood donors in Brazil, 2019-2021. [PDF]

Vox Sang
Abstract Background and Objectives Arbovirus infections are a major public health concern in Brazil and an ongoing blood safety concern. Periodic outbreaks of such infections are common in the general population. This study aimed to establish the rates of dengue, chikungunya and Zika virus (DENV, CHIKV, ZIKV) RNAemia among blood donors at six public ...
Grebe E, Buccheri R, Montalvo L, Kashima S, Miranda C, Milani P, Stone M, Livezey K, Capuani L, Alencar CS, Amorim L, Loureiro P, Ribeiro M, da Costa AG, Mendrone A, Busch MP, Sabino EC, Custer B, Recipient Epidemiology and Donor Evaluation Study‐IV‐Pediatric (REDS‐IV‐P) Brazil.   +18 more
europepmc   +2 more sources

Chikungunya virus infection: molecular biology, clinical characteristics, and epidemiology in Asian countries

Journal of Biomedical Science, 2021
Chikungunya virus (CHIKV) is a re-emerging mosquito-borne human pathogen that causes chikungunya fever, which is typically accompanied by severe joint pain. In Asia, serological evidence indicated that CHIKV first emerged in 1954. From the 1950’s to 2005,
Sarawut Khongwichit, Jira Chansaenroj, Chintana Chirathaworn, Yong Poovorawan   +3 more
doaj   +2 more sources

Chikungunya Virus Diagnosis: A Review of Current Antigen Detection Methods

Tropical Medicine and Infectious Disease, 2023
Chikungunya is a mosquito-borne viral disease caused by the chikungunya virus (CHIKV). CHIKV is expanding at an alarming rate, potentially spreading and establishing endemicity in new areas where competent vectors are present.
Fredy Brice Nemg Simo, Felicity Jane Burt, Nigel Aminake Makoah   +2 more
doaj   +2 more sources

Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate

Scientific Reports, 2022
Chikungunya virus (CHIKV) is the causative agent of Chikungunya fever, an acute febrile and arthritogenic illness with no effective treatments available. The development of effective therapeutic strategies could be significantly accelerated with detailed
Marjorie C. L. C. Freire, Luis G. M. Basso, Luis F. S. Mendes, Nathalya C. M. R. Mesquita, Melina Mottin, Rafaela S. Fernandes, Lucca R. Policastro, Andre S. Godoy, Igor A. Santos, Uriel E. A. Ruiz, Icaro P. Caruso, Bruna K. P. Sousa, Ana C. G. Jardim, Fabio C. L. Almeida, Laura H. V. G. Gil, Carolina H. Andrade, Glaucius Oliva   +16 more
doaj   +2 more sources

A retrospective investigation for the seroprevalence of Chikungunya virus and its co-existence with Dengue virus in Pakistani population, 2014–2015 [PDF]

Scientific Reports
Dengue and Chikungunya are caused by the same vectors, Aedes aegypti and Aedes albopictus. Both mosquitoes are endemic in Pakistan, and various parts of the country experienced outbreaks of Dengue virus over the past decades.
Darakhshan Guhar, Kiran A. Qadir, Fiza Khan, Shafqat F. Rehmani, Sayyada G. Nadeem   +4 more
doaj   +2 more sources

Continuous Circulation of Chikungunya Virus during COVID-19 Pandemic in Jambi, Sumatra, Indonesia

Tropical Medicine and Infectious Disease, 2022
Chikungunya fever is a self-limiting viral illness that is caused by the chikungunya virus (CHIKV). CHIKV is found in multiple provinces of Indonesia, with clustered local outbreaks.
Marsha Sinditia Santoso, Sotianingsih Haryanto, Fadil Rulian, Rahma F. Hayati, Amanda Kristiani, Rini Kartika, Benediktus Yohan, Martin L. Hibberd, R. Tedjo Sasmono   +8 more
doaj   +1 more source

Calpain-2 protein influences chikungunya virus replication and regulates vimentin rearrangement caused by chikungunya virus infection

Frontiers in Microbiology, 2023
Chikungunya fever (CHIF), a vector-borne disease transmitted mainly by Aedes albopictus and Aedes aegypti, is caused by Chikungunya virus (CHIKV) infection. To date, it is estimated that 39% of the world’s population is at risk of infection for living in
Jia Li, Jia Li, Jia Li, Kang Zheng, Huilong Shen, Hua Wu, Chengsong Wan, Renli Zhang, Zhimin Liu   +8 more
doaj   +1 more source