Results 21 to 30 of about 6,129,228 (249)

scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data

open access: yesGenome Biology, 2020
Single-cell chromatin accessibility sequencing has become a powerful technology for understanding epigenetic heterogeneity of complex tissues. However, there is a lack of open-source software for comprehensive processing, analysis, and visualization of ...
Wenbao Yu   +4 more
doaj   +1 more source

International incidence of childhood cancer, 2001–10: a population-based registry study

open access: yesThe Lancet Oncology, 2017
Summary Background Cancer is a major cause of death in children worldwide, and the recorded incidence tends to increase with time. Internationally comparable data on childhood cancer incidence in the past two decades are scarce.
E. Steliarova-Foucher   +230 more
semanticscholar   +1 more source

Childhood cancer: Estimating regional and global incidence.

open access: yesCancer Epidemiology, 2020
BACKGROUND Most of the world's population is not covered by cancer surveillance systems or vital registration, and worldwide/UN-regional cancer incidence is estimated using a variety of methods. Quantifying the cancer burden in children (
W. Johnston   +5 more
semanticscholar   +1 more source

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

open access: yesHaematologica, 2018
Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia.
Paul. B. Sinclair   +18 more
doaj   +1 more source

Life Expectancy of Adult Survivors of Childhood Cancer Over 3 Decades.

open access: yesJAMA Oncology, 2020
Importance Advances in childhood and adolescent cancer treatment have been associated with increased rates of cure during the past 3 decades; however, improvement in adult life expectancy for these individuals has not yet been reported.
J. Yeh   +12 more
semanticscholar   +1 more source

Equivalent doses for anticancer agents used in pediatric oncology: A literature review and evaluation of a novel approach for conversion factors

open access: yesCancer Reports, 2023
Background Epidemiological research on late effects of therapy shows the necessity to aggregate chemotherapy agents to substance classes. This requires using conversion factors by substance classes.
Meike Ressing   +11 more
doaj   +1 more source

Scaling Up the Surveillance of Childhood Cancer: A Global Roadmap

open access: yesJournal of the National Cancer Institute, 2020
The World Health Organization recently launched the Global Initiative for Childhood Cancer aiming to substantially increase survival among children with cancer by 2030.
M. Piñeros   +4 more
semanticscholar   +1 more source

Quality of life of caregivers and impact on the nuclear family of children with leukaemia in the National Cancer Institute of Sri Lanka [PDF]

open access: yes, 2015
Childhood leukaemia is the commonest cancer in children aged below 15 years. A diagnosis of childhood leukaemia is a devastating experience for any parent. This hospital-based descriptive cross sectional study aimed to assess the quality of life (QOL) of
Goonawardena, C S E   +2 more
core   +1 more source

Motor skill delays in pre-school children with leukemia one year after treatment: Hematopoietic stem cell transplantation therapy as an important risk factor [PDF]

open access: yes, 2017
CNS-directed therapies for the treatment of leukemia can adversely affect the acquisition of new skills, such as reading/writing and math. Two years after the end of treatments, children show gross and fine motor skill delays that may persist even when ...
Barbara Tosetto   +6 more
core   +13 more sources

Income disparities between adult childhood cancer survivors and their peers—A register‐based cohort study from the SALiCCS research programme

open access: yesCancer Medicine, 2023
Background Childhood cancer survivors face various adverse consequences. This Nordic register‐based cohort study aimed to assess whether survivors of childhood cancer are more likely to have low income than their peers.
Anniina Kyrönlahti   +15 more
doaj   +1 more source

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