Results 241 to 250 of about 7,246,923 (291)

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

open access: yesAdvanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang   +11 more
wiley   +1 more source

Nurturing environments for shaping trauma-responsive care and recovery: a realist coproduction study protocol. [PDF]

open access: yesFront Child Adolesc Psychiatry
Parry S   +8 more
europepmc   +1 more source

Playing It Differently: Using Performance-Based Interviewing to Engage Children in Healthcare Research. [PDF]

open access: yesHealth Expect
Treadgold C   +10 more
europepmc   +1 more source

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