Chimeric Protein-LG and Protein-LAG sandwich ELISA v1 [PDF]
This ELISA is used to study the interactions between protein-LG (SpLG) and protein-LAG (PLAG) with different immunoglobulin preparations from mammals and avian species.
openaire +6 more sources
Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures [PDF]
Vesivirus 2117 is an adventitious agent that in 2009, was identified as a contaminant of CHO cells propagated in bioreactors at a pharmaceutical manufacturing plant belonging to Genzyme.
Bhella, David +8 more
core +1 more source
New simplified molecular design for functional T cell receptor [PDF]
We have produced a chimeric single-chain T cell receptor (TcR) that combines the specific antibody recognition function and TcR/CD3 signaling properties within the same polypeptide chain.
Clevers +23 more
core +1 more source
Protlego: a Python package for the analysis and design of chimeric proteins [PDF]
Abstract Motivation Duplication and recombination of protein fragments have led to the highly diverse protein space that we observe today. By mimicking this natural process, the design of protein chimeras via fragment recombination has proven experimentally successful and has opened a new era ...
Noelia Ferruz +2 more
openaire +3 more sources
Incorporation of chimeric gag protein into retroviral particles [PDF]
The product of the Rous sarcoma virus (RSV) gag gene, Pr76gag, is a polyprotein precursor which is cleaved by the viral protease to yield the major structural proteins of the virion during particle assembly in avian host cells. We have recently shown that myristylated forms of the RSV Gag protein can induce particle formation with very high efficiency ...
R A, Weldon +3 more
openaire +2 more sources
Structure-Guided Recombination Creates an Artificial Family of Cytochromes P450 [PDF]
Creating artificial protein families affords new opportunities to explore the determinants of structure and biological function free from many of the constraints of natural selection.
Arnold, Frances H. +5 more
core +1 more source
Protein Model and Function Analysis in Quorum-Sensing Pathway of Vibrio qinghaiensis sp.-Q67
Bioluminescent bacteria are mainly found in marine habitats. Vibrio qinghaiensis sp.-Q67 (Q67), a nonpathogenic freshwater bacterium, has been a focus due to its wide use in the monitoring of environmental pollution and the assessment of toxicity ...
Ze-Jun Wang +4 more
doaj +1 more source
Nanobody based dual specific CARs [PDF]
Recent clinical trials have shown that adoptive chimeric antigen receptor (CAR) T cell therapy is a very potent and possibly curative option in the treatment of B cell leukemias and lymphomas.
Abken, Hinrich +8 more
core +2 more sources
Construction and characterization of pyocin-colicin chimeric proteins [PDF]
Chimeric proteins were constructed from pyocin S1 or S2 and colicin E3 or E2, and their characteristics were investigated with special reference to the domain structure. The nuclease domains were interchangeable between two bacteriocins so that a new kind of pyocin, with RNase activity, was created.
M, Kageyama +3 more
openaire +2 more sources
Evolution of plant ribosome-inactivating proteins [PDF]
This contribution presents an updated analysis of the evolution of ribosome-inactivating proteins (RIPs) in plants. All evidence suggests that an ancestor of modern seed plants developed the RIP domain at least 300 million years ago.
Peumans, Willy J, Van Damme, Els
core +1 more source

