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Chinese hamsters and diabetes mellitus
Acta Diabetologica Latina, 1964In the Chinese Hamster inbreeding and exposure to stressful situations are capable of precipitating Diabetes mellitus. The condition produced by gene-mutation is hereditary and the signs and symptoms of the disease, including degenerative vascular lesions, resemble closely those observed in human subjects.
Otakar V. Sirek, Anna Sirek
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Lysosomes in Chinese Hamster fibroblasts in culture
Experimental Cell Research, 1964Abstract A modified Gomori method for staining cultured cells for acid phosphatase is described, which permits a chosen cell to be photographed after various times of incubation in the substrate mixture, and thereby assists in the identification of artefacts.
J.T. Dingle, M.R. Daniel, T.R. Munro
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Maturation of spermatozoa in the epididymis of the Chinese hamster
American Journal of Anatomy, 1985AbstractChinese hamster spermatozoa gain their ability to move when they descend from the testis to the distal part of the caput epididymis, but it is not until they enter the corpus epididymis that they become capable of fertilizing eggs. The maturation of the spermatozoa proceeds as they further descend the tract and perhaps continues even in the vas
Ryuzo Yanagimachi +4 more
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Delayed mutation in Chinese hamster cells
Somatic Cell and Molecular Genetics, 1987The possibility was examined that mutational events can be delayed for more than one or two cell divisions following treatment of Chinese hamster cells with the DNA alkylating agent ethyl methane sulfonate. If mutations in mammalian cells are delayed, the proportion of mutant cells in colonies grown from single mutagen-treated cells will reflect the ...
Ronald Weinstein +5 more
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Diabetes in the Chinese hamster
1996According to Yerganian,1 the first recorded experimental use of the Chinese hamster, Cricetulus griseus, was for the identification of pneumococcal types prior to treatment of pneumonia at the Peking Medical College Hospital in 1919 because laboratory mice were not available.2 The Chinese or “striped-back” hamster is recognized by the black stripe that
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Proteomic profiling of a high-producing Chinese hamster ovary cell culture.
Analytical Chemistry, 2009The productivity of mammalian cell culture expression systems is critically important to the production of biopharmaceuticals. In this study, a high-producing Chinese hamster ovary cell culture which was transfected with the apoptosis inhibitor Bcl-X(L ...
Tyler Carlage +6 more
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Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter.
Science, 1979Wild-type Chinese hamster V79 cells (6-thioguanine-sensitive) reduce the recovery of 6-thioguanine-resistant cells when they are cultured together at high densities, through a form of intercellular communication (metabolic cooperation).
L. Yotti, C. Chang, J. Trosko
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Architecture of the Chinese hamster metaphase chromosome
Chromosoma, 1971The development of procedures for the isolation of unfixed metaphase chromosomes has made feasible a direct analysis of their morphology. Wholemount stereo electron microscopy was used to examine intact and partially disrupted chromosomes produced by physical shearing and extraction with salt and urea solutions.
Wayne Wray, Elton Stubblefield
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Histone phosphorylation and chromatin structure during mitosis in Chinese hamster cells.
European Journal of Biochemistry, 1978Histone phosphorylation and chromatin structure were examined in synchronized CHO Chinese hamster cells during progression through mitosis. Cell population distribution in various phases of mitosis was determined by electron microscopy.
L. Gurley +4 more
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Pachytene mapping of the male Chinese hamster
Cytogenetic and Genome Research, 1976Minced seminiferous tubules of male Chinese hamsters, when treated with a mixture of trypsin (one part) and McCoy’s 5a growth medium with 20 % fetal calf serum (nine parts) at 4° C, washed twice with the regular growth medium, incubated at 37° C in growth medium for 4 h, and harvested without Colcemid and hypotonic pretreatments, gave excellent ...
Amara Markvong, T. C. Hsu, S. Pathak
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