Results 81 to 90 of about 92,663 (299)

Genome-wide association study of hippocampal BOLD-CBF correlation in Han Chinese population

, 2023
GWAS summary of hippocampal BOLD-CBF correlation in Han Chinese ...
Hui Xue (16410183)
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

A genetic contribution from the Far East into Ashkenazi Jews via the ancient Silk Road

, 2015
Contemporary Jews retain a genetic imprint from their Near Eastern ancestry, but obtained substantial genetic components from their neighboring populations during their history.
Jits van Straten, Li, Yu-Chun, Wang, Hua Wei, Wen Zhang, Yao, Yong-Gang, Hua-Wei Wang, Wang, Hua-Wei, Yu-Chun Li, Qing-Peng Kong, Yao, Yong Gang, Tian, Jiao-Yang, Li, Yu Chun, Kong, Qing-Peng, Jiao-Yang Tian, Richards, Martin B., Yong-Gang Yao, Tian, Jiao Yang, van Straten, Jits, Zhang, Wen, Kong, Qing Peng, Martin B. Richards   +20 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Tyrosinase gene mutations in the Chinese Han population with OCA1

Genetics Research, 2014
SummaryOculocutaneous albinism (OCA) is a heterogeneous autosomal recessive genetic disorder that affects melanin synthesis. OCA results in reduced or absent pigmentation in the hair, skin and eyes. Type 1 OCA (OCA1) is the result of tyrosinase (TYR) gene mutations and is a severe disease type.
Ning, Liu, Xiang Dong, Kong, Hui Rong, Shi, Qing Hua, Wu, Miao, Jiang   +4 more
openaire   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Association of RPS26 gene polymorphism with different types of diabetes in Chinese individuals

Journal of Diabetes Investigation
Aims/Introduction Different types of diabetes show distinct genetic characteristics, but the specific genetic susceptibility factors remain unclear. Our study aimed to explore the associations between the ribosomal protein S26 (RPS26) gene rs1131017 ...
Rong Song, Lingxiang Xie, Jin Ding, Yan Chen, Hailan Zou, Haipeng Pang, Yiman Peng, Ying Xia, Zhiguo Xie, Xia Li, Yang Xiao, Zhiguang Zhou, Jingyi Hu   +12 more
doaj   +1 more source

The combined forensic efficacy of AGCU X19 system in Han Chinese population.

, 2018
The combined forensic efficacy of AGCU X19 system in Han Chinese population.
Guanglin He (5775206), Pengyu Chen (1312830), Jida Li (5775215), Xing Zou (2118862), Huiru Bai (5775212), Fuquan Jia (5775209), Jian Yu (141239), Mengge Wang (5526449), Yanyan Han (523045)   +8 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Genetic polymorphisms in the TERT gene and susceptibility to non-small cell lung cancer in a Chinese Han population

Cancer Management and Research, 2018
Chuanyin Li,1,* Xiaona Wang,1,* Yingfu Li,2 Xinwen Zhang,1 Mingbo Sun,1 Shuyuan Liu,1 Le Sun,3 Li Shi,1 Yufeng Yao1 1Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming 650118, China; 2Department ...
Li C, Wang X, Li Y, Zhang X, Sun M, Liu S, Sun L, Shi L, Yao Y   +8 more
doaj