Results 81 to 90 of about 771,775 (343)

Effects of AQP4 and KCNJ10 Gene Polymorphisms on Drug Resistance and Seizure Susceptibility in Chinese Han Patients with Focal Epilepsy

Neuropsychiatric Disease and Treatment, 2020
Haoyue Zhu, Mengqi Zhang, Yujiao Fu, Hongyu Long, Wenbiao Xiao, Li Feng, Bo Xiao, Luo Zhou Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, People’s Republic of ChinaCorrespondence: Luo ZhouDepartment of ...
Zhu H, Zhang M, Fu Y, Long H, Xiao W, Feng L, Xiao B, Zhou L   +7 more
doaj  

Genetic variants at 20p11 confer risk to androgenetic alopecia in the Chinese Han population. [PDF]

PLoS ONE, 2013
BACKGROUND: Androgenetic alopecia (AGA) is a well-characterized type of progressive hair loss commonly seen in men, with different prevalences in different ethnic populations. It is generally considered to be a polygenic heritable trait.
Bo Liang, Chunjun Yang, Xianbo Zuo, Yang Li, Yantao Ding, Yujun Sheng, Fusheng Zhou, Hui Cheng, Xiaodong Zheng, Gang Chen, Zhengwei Zhu, Jun Zhu, Xuhui Fu, Tao Wang, Ying Dong, Dawei Duan, Xianfa Tang, Huayang Tang, Jinping Gao, Liangdan Sun, Sen Yang, Xuejun Zhang   +21 more
doaj   +1 more source

Tag SNPs in long non-coding RNA H19 contribute to susceptibility to gastric cancer in the Chinese Han population

OncoTarget, 2015
Long non-coding RNA (lncRNA) H19 is involved in tumor development, progression, and metastasis. This case-control study assessed the association between H19 genetic variants and susceptibility to gastric cancer (GC) in a Chinese Han population.
Chao Yang, R. Tang, Xiang Ma, Younan Wang, Dakui Luo, Zekuan Xu, Yi Zhu, Li Yang   +7 more
semanticscholar   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

DNA methylation age is not affected in psoriatic skin tissue

Clinical Epigenetics, 2018
Background Psoriasis (Ps) is a common chronic inflammatory skin disease. The keratinocytes of psoriatic skin defy normal apoptosis and exhibit active cell proliferation.
Changbing Shen, Leilei Wen, Randy Ko, Jing Gao, Xue Shen, Xianbo Zuo, Liangdan Sun, Yi-Hsiang Hsu, Xuejun Zhang, Yong Cui, Meng Wang, Fusheng Zhou   +11 more
doaj   +1 more source

Diversified pattern of the human colorectal cancer microbiome [PDF]

, 2013
BACKGROUND: The aim of this study is to expand existing knowledge about the CRC-associated microbiome among Han Chinese, and to further discover the variation pattern of the human CRC microbiome across all population. FINDINGS: Using pyrosequencing-based
Hong Fan, Huiqin Zhai, Jiawei Geng, Xiaodan Tang, Zhigang Zhang   +4 more
core   +1 more source

Association of NLRP3 polymorphisms with susceptibility to primary gouty arthritis in a Chinese Han population

Clinical Rheumatology, 2017
The NLRP3-interleukin1β (IL1β) signaling pathway is involved in monosodium urate (MSU)-mediated inflammation. The aim of this present study was to determine whether single nucleotide polymorphisms (SNPs) in the NLRP3 gene are associated with ...
Quan-Bo Zhang, Y. Qing, Yonglong He, Wen-guang Xie, Jingguo Zhou   +4 more
semanticscholar   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Associations of genetic polymorphisms of the vitamin D pathway with blood pressure in a Han Chinese population

Clinical and Experimental Hypertension, 2019
Vitamin D deficiency can lead to high blood pressure. Polymorphisms in the vitamin D hydroxylase gene have been associated with serum vitamin D levels in some Western countries.
Xiaoman Ye, Jian Jia, Ning Zhang, Haixia Ding, Yiyang Zhan   +4 more
doaj   +1 more source

Genetic analysis of the ATP11B gene in Chinese Han population with cerebral small vessel disease

BMC Genomics, 2022
Background A loss-of-function mutation in ATPase phospholipid transporting 11-B (putative) (ATP11B) gene causing cerebral small vessel disease (SVD) in vivo, and a single intronic nucleotide polymorphism in ATP11B: rs148771930 that was associated with ...
Wen-Kai Yu, Yun-Chao Wang, Yuan Gao, Chang-He Shi, Yu Fan, Lu-Lu Yu, Zi-Chen Zhao, Shan-Shan Li, Yu-Ming Xu, Yu-Sheng Li   +9 more
doaj   +1 more source