Results 21 to 30 of about 459,773 (306)

A simple method for generating high-resolution maps of genome-wide protein binding

open access: yeseLife, 2015
Chromatin immunoprecipitation (ChIP) and its derivatives are the main techniques used to determine transcription factor binding sites. However, conventional ChIP with sequencing (ChIP-seq) has problems with poor resolution, and newer techniques require ...
Peter J Skene, Steven Henikoff
doaj   +1 more source

Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease. [PDF]

open access: yes, 2013
BACKGROUND: Vitamin D insufficiency has been implicated in autoimmunity. ChIP-seq experiments using immune cell lines have shown that vitamin D receptor (VDR) binding sites are enriched near regions of the genome associated with autoimmune diseases.
Heather Hanwell   +34 more
core   +1 more source

ILM-MLOlab/ChIP-seq-GATA1: v.1.0.0

open access: yes, 2022
Here is the depository for the code and source data for ChIP-seq GATA1 ...
mattiasmoller, ILM-MLOlab
core   +1 more source

Genomic location analysis by ChIP‐Seq [PDF]

open access: yesJournal of Cellular Biochemistry, 2009
AbstractThe interaction of a multitude of transcription factors and other chromatin proteins with the genome can influence gene expression and subsequently cell differentiation and function. Thus systematic identification of binding targets of transcription factors is key to unraveling gene regulation networks.
Artem, Barski, Keji, Zhao
openaire   +2 more sources

ChIP-seq extended data.

open access: yes, 2022
A) Log2 immunoprecipitate/Input ChIP-seq data from each replicate (2x AP2-EXP::GFP and 1xAP2-EXP::HA) of AP2-EXP ChIP-seq visualized by IGV at a representative DNA locus.
Charisse Flerida A. Pasaje (13949382)   +13 more
core   +1 more source

An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition. [PDF]

open access: yesPLoS ONE, 2016
Chromatin immunoprecipitation and DNA sequencing (ChIP-seq) has been instrumental in inferring the roles of histone post-translational modifications in the regulation of transcription, chromatin compaction and other cellular processes that require ...
Brian Egan   +16 more
doaj   +1 more source

ENCODE-DCC/chip-seq-pipeline2: v2.2.0

open access: yes, 2022
Upgrade Caper to >=2.2.0 for new HPC features. $ pip install caper>=2.2.0 --upgrade Conda environment name change: encode-chip-seq-pipeline -> encd-chip Please reinstall your Conda environment after updating pipeline's git repo.
Jin wook Lee   +5 more
core   +1 more source

Low-Cell-Number Epigenome Profiling Aids the Study of Lens Aging and Hematopoiesis

open access: yesCell Reports, 2015
Understanding how chromatin modification regulates development and disease can be limited by available material. Despite recent progress, balancing high-quality and reliable mapping using chromatin-immunoprecipitation-based deep sequencing (ChIP-seq ...
Xiaobin Zheng   +5 more
doaj   +1 more source

intePareto: an R package for integrative analyses of RNA-Seq and ChIP-Seq data

open access: yesBMC Genomics, 2020
Background RNA-Seq, the high-throughput sequencing (HT-Seq) of mRNAs, has become an essential tool for characterizing gene expression differences between different cell types and conditions.
Yingying Cao   +2 more
doaj   +1 more source

CMT: a constrained multi-level thresholding approach for ChIP-Seq data analysis. [PDF]

open access: yesPLoS ONE, 2014
Genome-wide profiling of DNA-binding proteins using ChIP-Seq has emerged as an alternative to ChIP-chip methods. ChIP-Seq technology offers many advantages over ChIP-chip arrays, including but not limited to less noise, higher resolution, and more ...
Iman Rezaeian, Luis Rueda
doaj   +1 more source

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