Results 131 to 140 of about 459,773 (306)

ChIP-seq summary.

open access: yes, 2014
(A) Schematic of our RNA-seq and ChIP-seq assays, showing the various antibodies used for ChIP-seq and the total number of peaks obtained for each antibody and treatment. (B) Overlap between DMSO and rifampin treated ChIP-seq peaks for each antibody.
Anuradha Ramamoorthy (638650)   +14 more
core   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye   +9 more
wiley   +1 more source

Perm-seq analysis of GM12878 Ctcf and Sin3a ChIP-seq dataset with DNase-seq and Histone ChIP-seq priors.

open access: yes, 2015
(a) Heatmap of normalized DNase-seq and Histone ChIP-seq read counts for the [-1000 bps, +1000 bps] window anchored at GM12878 Ctcf peak summits depicted by the vertical dashed lines.
Constanza Rojo (816204)   +6 more
core   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

open access: yesAdvanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He   +10 more
wiley   +1 more source

ENCODE-DCC/chip-seq-pipeline2: v2.2.2

open access: yes
<p>Fixed broken docker cache and rebuilt docker image, and then synced with atac-seq-pipeline's image.</p ...
Jin wook Lee   +5 more
core   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

ChIP-seq and RNA-seq identify CdpR regulons in P. aeruginosa genome.

open access: yes, 2016
(A) The positions of the CdpR-binding peaks are presented in a pie chart. (B) CdpR binds to the inside sequence of PA0440. (C) Pie chart presents the percentages of CdpR targets with functional categories defined in the Pseudomonas database (http ...
Xin Deng (186800)   +8 more
core   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

open access: yesAdvanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou   +10 more
wiley   +1 more source

ChIP-seq analysis of ERG and FLI1 in HUVECs.

open access: yes, 2018
(A) Venn diagram showing the overlap between the ChIP-seq peaks of ERG and FLI1. (B) Peak distributions of ERG and FLI1 in the indicated genomic regions. (C) Motif analysis of ERG and FLI1 in HUVECs.
Hiroyuki Aburatani (162634)   +7 more
core   +1 more source

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