Results 111 to 120 of about 928,240 (334)

BayesPeak: Bayesian analysis of ChIP-seq data [PDF]

BMC Bioinformatics, 2009
High-throughput sequencing technology has become popular and widely used to study protein and DNA interactions. Chromatin immunoprecipitation, followed by sequencing of the resulting samples, produces large amounts of data that can be used to map genomic features such as transcription factor binding sites and histone modifications.Our proposed ...
Spyrou, Christiana, Stark, Rory, Lynch, Andy G, Tavaré, Simon   +3 more
openaire   +3 more sources

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

aFARP-ChIP-seq, a convenient and reliable method for genome profiling in as few as 100 cells with a capability for multiplexing ChIP-seq

Epigenetics, 2019
Much effort has been devoted to understand how chromatin modification regulates development and disease. Despite recent progress, however, it remains difficult to obtain high-quality epigenomic maps using chromatin-immunoprecipitation-coupled deep ...
Wenbin Liu, Sibiao Yue, Xiaobin Zheng, Minjie Hu, Jia Cao, Yixian Zheng   +5 more
doaj   +1 more source

7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs

BMC Genomics, 2019
Background Knowledge of the three-dimensional structure of the genome is necessary to understand how gene expression is regulated. Recent experimental techniques such as Hi-C or ChIA-PET measure long-range chromatin interactions genome-wide but are ...
Jonas Ibn-Salem, Miguel A. Andrade-Navarro   +1 more
doaj   +1 more source

Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation. [PDF]

, 2019
Genome wide association studies (GWAS) in obesity have identified a large number of noncoding loci located near genes expressed in the central nervous system.
Ahituv, Nadav, Eckalbar, Walter L, Inoue, Fumitaka, Matharu, Navneet, Murphy, Karl K, Vaisse, Christian, Wang, Yi   +6 more
core   +1 more source

VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer

Genome Biology, 2019
VirtUaL ChIP-seq Analysis through Networks (VULCAN) infers regulatory interactions of transcription factors by overlaying networks generated from publicly available tumor expression data onto ChIP-seq data.
Andrew N. Holding, F. Giorgi, Amanda Donnelly, Amy E Cullen, S. Nagarajan, L. Selth, F. Markowetz   +6 more
semanticscholar   +1 more source

Transcriptomic and ChIP seq data

, 2021
Transcriptomic and ChIP seq ...
Wicky, Chantal, Rodriguez-Crespo, David, Nanchen, Magali, Rajopadhye, Shweta   +3 more
openaire   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

In silico pooling of ChIP-seq control experiments.

PLoS ONE, 2014
As next generation sequencing technologies are becoming more economical, large-scale ChIP-seq studies are enabling the investigation of the roles of transcription factor binding and epigenome on phenotypic variation.
Guannan Sun, Rajini Srinivasan, Camila Lopez-Anido, Holly A Hung, John Svaren, Sündüz Keleş   +5 more
doaj   +1 more source

ChIP-chip versus ChIP-seq: Lessons for experimental design and data analysis

BMC Genomics, 2011
Background Chromatin immunoprecipitation (ChIP) followed by microarray hybridization (ChIP-chip) or high-throughput sequencing (ChIP-seq) allows genome-wide discovery of protein-DNA interactions such as transcription factor bindings and histone ...
Karchenko Peter V, Bishop Eric, Ho Joshua WK, Nègre Nicolas, White Kevin P, Park Peter J   +5 more
doaj   +1 more source