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ChIP-Seq and the Complexity of Bacterial Transcriptional Regulation

2012
Transcription factors (TFs) play a central role in regulating gene expression in all bacteria. Yet, until recently, studies of TF binding were limited to a small number of factors at a few genomic locations. Chromatin immunoprecipitation followed by sequencing enables mapping of binding sites for TFs in a global and high-throughput fashion.
James, Galagan   +2 more
openaire   +2 more sources

Modelling ChIP-seq Data Using HMMs

2017
Chromatin ImmunoPrecipitation-sequencing (ChIP-seq) experiments have now become routine in biology for the detection of protein binding sites. In this chapter, we show how hidden Markov models can be used for the analysis of data generated by ChIP-seq experiments.
openaire   +2 more sources

Introduction to ChIP-Seq

2015
Introduction to ChIP-seq data analysis. Overview of quality control, mapping, peak calling and downstream analysis methods.
openaire  

CoBRA: Containerized Bioinformatics Workflow for Reproducible ChIP/ATAC-Seq Analysis

Genomics, Proteomics and Bioinformatics, 2021
Xintao Qiu, Avery Feit, Yingtian Xie
exaly  

ChIP-Seq

2010
Philippe Lefrançois   +2 more
openaire   +1 more source

Impact of artifact removal on ChIP quality metrics in ChIP-seq and ChIP-exo data

Frontiers in Genetics, 2014
Thomas S Carroll   +2 more
exaly  

ChIP-seq: Using high-throughput sequencing to discover protein–DNA interactions

Methods, 2009
Dominic Schmidt   +2 more
exaly  

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