Results 1 to 10 of about 75,340 (210)

Chiral chromatography and surface chirality of carbon nanoparticles [PDF]

open access: yesChirality, 2022
AbstractChiral carbon nanoparticles (CNPs) represent a rapidly evolving area of research for optical and biomedical technologies. Similar to small molecules, applications of CNPs as well as fundamental relationships between their optical activity and structural asymmetry would greatly benefit from their enantioselective separations by chromatography ...
Misché A. Hubbard   +6 more
openaire   +4 more sources

Biomimetic properties and estimated in vivo distribution of chloroquine and hydroxy-chloroquine enantiomers

open access: yesADMET and DMPK, 2021
Chloroquine and hydroxy-chloroquine already established as anti-malarial and lupus drugs have recently gained renewed attention in the fight against the Covid-19 pandemic.
Klara Livia Valko, Tong Zhang
doaj   +1 more source

Emerging Developments in Separation Techniques and Analysis of Chiral Pharmaceuticals

open access: yesMolecules, 2023
Chiral separation, the process of isolating enantiomers from a racemic mixture, holds paramount importance in diverse scientific disciplines. Using chiral separation methods like chromatography and electrophoresis, enantiomers can be isolated and ...
Sulaiman Al-Sulaimi   +5 more
doaj   +1 more source

Metal–Organic Frameworks-Based Analytical Devices for Chiral Sensing and Separations: A Review (2012–2022)

open access: yesChemosensors, 2022
Metal–organic frameworks (MOFs), as high-surface-area materials, have shown promise in various areas of application, such as chiral sensing and separation, due to their flexibility in design and organized porous cages.
Soodabeh Hassanpour   +2 more
doaj   +1 more source

An electronic circular dichroism spectroscopy method for the quantification of L- and D-amino acids in enantiomeric mixtures [PDF]

open access: yesRoyal Society Open Science, 2021
Rapid quantitative analysis of single chiral amino acid (aa) was achieved using circular dichroism (CD) with data analysis by standard calibration curve.
Ruiwen Ding, Jianxi Ying, Yufen Zhao
doaj   +1 more source

Chiral Micellar Electrokinetic Chromatography

open access: yesJournal of Chromatography A, 2020
The potential of Micellar Electrokinetic Chromatography to achieve enantiomeric separations is reviewed in this article. The separation principles and the most frequently employed separation strategies to achieve chiral separations by Micellar Electrokinetic Chromatography are described.
Marina Alegre, María Luisa   +2 more
openaire   +3 more sources

Chiral Separations in Preparative Scale: A Medicinal Chemistry Point of View

open access: yesMolecules, 2020
Enantiomeric separation is a key step in the development of a new chiral drug. Preparative liquid chromatography (LC) continues to be the technique of choice either during the drug discovery process, to achieve a few milligrams, or to a scale-up during ...
Madalena M.M. Pinto   +2 more
doaj   +1 more source

Enantioselective Liquid Chromatographic Separations Using Macrocyclic Glycopeptide-Based Chiral Selectors

open access: yesMolecules, 2021
Numerous chemical compounds of high practical importance, such as drugs, fertilizers, and food additives are being commercialized as racemic mixtures, although in most cases only one of the isomers possesses the desirable properties. As our understanding
Róbert Berkecz   +3 more
doaj   +1 more source

Chiral Separations of Pyrethroic Acids Using Cyclodextrin Selectors

open access: yesMolecules, 2022
Pyrethroid insecticides are broadly used. They have low toxicity for warm-blooded living creatures, but high toxicity for both insects and fish. Therefore, it is important to reduce the environmental impact of pyrethroids.
Zoltán Juvancz   +4 more
doaj   +1 more source

Volatile Composition and Enantiomeric Distribution of Spanish Sage ( Subsp [Vahl] Gams) From Spain

open access: yesNatural Product Communications, 2022
Background: Spanish sage ( Salvia officinalis subsp . lavandulifolia [Vahl] Gams) is historically an important medicinal plant with a myriad of uses. Methods: In this work, 11 S officinalis subsp.
Noura S. Dosoky   +3 more
doaj   +1 more source

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