Asymmetric synthesis of 2-substituted oxetan-3-ones via metalated SAMP/RAMP hydrazones [PDF]
, 2013 2-Substituted oxetan-3-ones can be prepared in good yields and enantioselectivities (up to 84% ee) by the metalation of the SAMP/RAMP hydrazones of oxetan-3-one, followed by reaction with a range of electrophiles that include alkyl, allyl, and benzyl ...
Beasley, Benjamin +3 more
core +1 more source
Preparative Scale Resolution of Enantiomers Enables Accelerated Drug Discovery and Development
Molecules, 2017 The provision of pure enantiomers is of increasing importance not only for the pharmaceutical industry but also for agro-chemistry and biotechnology.
Hanna Leek, Shalini Andersson
doaj +1 more source
In pursuit of β-amino α-nitro β-trifluoromethyl ketones: nitro-Mannich vs Mannich-type reactions [PDF]
, 2017 The reactivity of alfa-nitro ketones with trifluoromethyl aldimines is studied for the first time. While under nitro-Mannich conditions only the facial stereoselectivity can be controlled, organocatalysed Mannich-type reactions allowed a complete control
Ballini +45 more
core +1 more source
Research Progress in the Residue Analysis and Risk Assessment of Chiral Pesticides in Tea [PDF]
Chaye kexueChiral pesticides have one or more enantiomers, and their biological activity, toxicity, environmental behavior, degradation and metabolism may be different.
HU Yue, NING Yating, LI Hongxia, LUO Fengjian, YIN Rongxiu, ZHANG Xinzhong
doaj +1 more source
Synthesis of Optically Active Bifunctional Building Blocks through Enantioselective Copper-Catalyzed Allylic Alkylation Using Grignard Reagents [PDF]
, 2007 Enantioselective copper-catalyzed allylic alkylations were performed on allylic bromides with a protected hydroxyl or amine functional group using several Grignard reagents and Taniaphos L1 as a ligand.
Feringa, Ben L., +3 more
core +1 more source
Metal-mediated intramolecular hydroamination and hydro(acy)alkoxylation reactions [PDF]
, 2012 This PhD thesis describes work undertaken to effect asymmetric catalysis in hydroamination and hydro(acy)alkoxylation reactions of allenes. The introductory Chapter provides an overview of recent advances in asymmetric heterofunctionalisation reactions ...
Arbour, Jannine Louise +1 more
core +1 more source
Enantiomeric Ratio Changes of Terpenes in Essential Oils from Hybrid Eucalyptus grandis × E. tereticornis and its Pure Species [PDF]
, 2018 Some Eucalyptus species produce oils with biological activities and the effect of their interspecifc hybridization on the enantiomeric composition of terpenes has not been reported.
Alvarez Costa, Agustin +4 more
core +2 more sources
Bile Salts in Chiral Micellar Electrokinetic Chromatography: 2000–2020
Molecules, 2021 Bile salts are naturally occurring chiral surfactants that are able to solubilize hydrophobic compounds. Because of this ability, bile salts were exploited as chiral selectors added to the background solution (BGS) in the chiral micellar electrokinetic ...
Raymond B. Yu, Joselito P. Quirino
doaj +1 more source
Absolute Configuration of Falcarinol (9Z-heptadeca-1,9-diene-4,6- diyn-3-ol) from Pastinaca sativa [PDF]
, 2013 Falcarinol (9Z-heptadeca-1,9-diene-4,6-diyn-3-ol; 1) is a polyacetylene commonly found in several plant families. The absolute configuration of naturally occurring 1 is not clear and contradictory results have been reported in the literature ...
Brunton, Nigel +4 more
core +1 more source
Chiral Selectors in Capillary Electrophoresis: Trends during 2017–2018
Molecules, 2019 Chiral separation is an important process in the chemical and pharmaceutical industries. From the analytical chemistry perspective, chiral separation is required for assessing the fit-for-purpose and the safety of chemical products.
Raymond B. Yu, Joselito P. Quirino
doaj +1 more source