Results 1 to 10 of about 2,801 (109)

Chiral Phosphoric Acid Promoted Chiral 1H NMR Analysis of Atropisomeric Quinolines [PDF]

Frontiers in Chemistry, 2021
An efficient enantioselective NMR analysis of atropisomeric quinolines in the promotion of chiral phosphoric acid is described, in which a variety of racemic 4-aryl quinolines were well-recognized with up to 0.17 ppm ΔΔδ value.
Junlin Wan, Jun Jiang, Juan Li
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Chiral phosphoric acid-catalyzed stereodivergent synthesis of trisubstituted allenes and computational mechanistic studies [PDF]

Nature Communications, 2020
Despite of the high demand of chiral allenes, their asymmetric synthesis remains a challenge for organic chemists. Here, the authors report a stereodivergent synthesis of trisubstituted allenes via asymmetric additions of oxazolones to activated 1,3 ...
Jiawen Wang, Sujuan Zheng, Subramani Rajkumar, Jinglei Xie, Na Yu, Qian Peng, Xiaoyu Yang   +6 more
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Chiral phosphoric acid-catalyzed asymmetric synthesis of helically chiral, planarly chiral and inherently chiral molecules [PDF]

Beilstein Journal of Organic Chemistry
Chiral molecules, distinguished by nonsuperimposability with their mirror image, play crucial roles across diverse research fields. Molecular chirality is conventionally categorized into the following types: central chirality, axial chirality, planar ...
Wei Liu, Xiaoyu Yang
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Chiral phosphoric acid-catalyzed asymmetric epoxidation of alkenyl aza-heteroarenes using hydrogen peroxide [PDF]

Nature Communications
The synthesis of chiral α-azaheteroaryl oxiranes via enantioselective catalysis is a formidable challenge due to the required complex stereoselectivity and diverse N-heterocyclic structures.
Hao-Chen Wen, Wei Chen, Meng Li, Chen Ma, Jian-Fei Wang, Aiping Fu, Shi-Qi Xu, Yi-Feng Zhou, Shao-Fei Ni, Bin Mao   +9 more
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Chiral phosphoric acid-catalyzed atroposelective iodination of N-arylindoles [PDF]

Communications Chemistry
Axially chiral indoles have garnered significant attention due to their synthetic and biological importance. However, atroposelective halogenation of this scaffold has been rarely explored.
Ahreum Kim, Hyun-A Cho, Byeongjun Oh, Jayoung Song, Yongseok Kwon   +4 more
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Stereoselective Biginelli-like reaction catalyzed by a chiral phosphoric acid bearing two hydroxy groups [PDF]

Beilstein Journal of Organic Chemistry, 2020
To develop new efficient stereoselective catalysts for Biginelli-like reactions, a chiral phosphoric acid bearing two hydroxy groups derived from ʟ-tartaric acid was successfully synthesized via highly regioselective transformations of enantiopure 1,1,4 ...
Xiaoyun Hu, Jianxin Guo, Cui Wang, Rui Zhang, Victor Borovkov   +4 more
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Atroposelective Synthesis of Biaryl Diamines and Amino Alcohols via Chiral Phosphoric Acid Catalyzed para-Aminations of Anilines and Phenols [PDF]

iScience, 2019
Summary: A versatile method for atroposelective synthesis of chiral biaryl diamines and amino alcohols has been developed via para-amination of anilines and phenols with azodicarboxylates enabled by chiral phosphoric acid catalysis.
Donglei Wang, Wei Liu, Mengyao Tang, Na Yu, Xiaoyu Yang   +4 more
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Chiral phosphoric acid-catalyzed enantioselective phosphinylation of 3,4-dihydroisoquinolines with diarylphosphine oxides [PDF]

Communications Chemistry, 2023
Catalytic enantioselective phosphinylation of imines with diarylphosphine oxides is a powerful approach to access chiral α-amino diarylphosphine oxides.
Yongbiao Guo, Ning Li, Junchen Li, Xiaojing Bi, Zhenhua Gao, Ya-Nan Duan, Junhua Xiao   +6 more
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Chiral phosphoric acid-catalyzed transfer hydrogenation of 3,3-difluoro-3H-indoles [PDF]

Beilstein Journal of Organic Chemistry
A convenient and efficient method for the synthesis of optically active difluoro-substituted indoline derivatives starting from the corresponding 3H-indoles by chiral phosphoric acid-catalyzed transfer hydrogenation was developed. Using Hantzsch ester as
Yumei Wang, Guangzhu Wang, Yanping Zhu, Kaiwu Dong   +3 more
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Chiral phosphoric acid catalyzed aminative dearomatization of α-naphthols/Michael addition sequence [PDF]

Nature Communications, 2019
Catalytic asymmetric dearomatization (CADA) reactions readily convert common aromatic compounds to diverse 3D chiral, polycyclic molecules. Here, the authors report an intermolecular asymmetric dearomatization of nucleophile-tethered α-naphthols ...
Zi-Lei Xia, Chao Zheng, Ren-Qi Xu, Shu-Li You   +3 more
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