Results 41 to 50 of about 2,722 (150)

Chiral Phosphoric Acid-Catalyzed Asymmetric Synthesis of Axially Chiral Arylpyrazole

Organic Letters
A chiral phosphoric acid-catalyzed efficient, operationally simple, general method for straightforward syntheses of axially chiral arylpyrazole employing N-alkyl of 3-aryl-5-aminopyrazoles reacting with azonaphthalenes was achieved. A wide variety of axially chiral heterobiaryl diamines in generally good yields with excellent enantioselectivities were ...
Shi-Wu Li, Yu Qi, Shujun Tong, Jiaqi Pu
openaire   +2 more sources

Asymmetric Friedel-Crafts Alkylation of Indole with Chalcones Catalyzed by Chiral Phosphoric Acids

Molecules, 2009
The reaction of indole with chalcones, to give Michael-type adducts, was found to occur with good efficiency (up to 98% yield) and moderate enantioselectivity (up to 52% e.e.) in the presence of a chiral BINOL-based phosphoric acid.
Maria Rosaria Acocella, Rosaria Villano, Arrigo Scettri   +2 more
doaj   +1 more source

A combined continuous microflow photochemistry and asymmetric organocatalysis approach for the enantioselective synthesis of tetrahydroquinolines

Beilstein Journal of Organic Chemistry, 2013
A continuous-flow asymmetric organocatalytic photocyclization–transfer hydrogenation cascade reaction has been developed. The new protocol allows the synthesis of tetrahydroquinolines from readily available 2-aminochalcones using a combination of ...
Erli Sugiono, Magnus Rueping
doaj   +1 more source

A chiral phosphoric acid catalyst for asymmetric construction of 1,3-dioxanes [PDF]

Chemical Communications, 2015
A chiral phosphoric acid catalyst enabled enantioselective 1,3-dioxane construction, useful for polyketide motif synthesis,viaa hemiacetalization/intramolecular oxy-Michael addition cascade.
Matsumoto, Akira, Asano, Keisuke, Matsubara, Seijiro   +2 more
openaire   +2 more sources

Bi(III)-Catalyzed Enantioselective Allylation Reactions of Ketimines

iScience, 2019
Summary: Chiral homoallylic amines not only are found in pharmaceutically relevant compounds but also serve as versatile building blocks for chemical synthesis.
Jie Wang, Qingxia Zhang, Biying Zhou, Chen Yang, Xin Li, Jin-Pei Cheng   +5 more
doaj   +1 more source

Enantioselective Reductions Promoted by (Cyclopentadienone)iron Complexes

CHIMIA, 2017
(Cyclopentadienone)iron complexes have recently gained widespread interest as cheap metal-based pre-catalysts for the reduction of carbonyl compounds and imines, thanks to their air- and moisture-stability and easy synthesis/purification.
Umberto Piarulli, Sofia Vailati Fachini, Luca Pignataro   +2 more
doaj   +1 more source

Catalytic enantioselective synthesis of inherently chiral calix[4]arenes via organocatalyzed aromatic amination enabled desymmetrization

Nature Communications
Inherently chiral calix[4]arenes represent a distinct class of chiral frameworks whose chirality arises from the dissymmetry of the entire molecule. Although these chiral scaffolds have been widely applied in various research fields, their catalytic ...
Mengyao Yuan, Wansen Xie, Shaoze Yu, Tong Liu, Xiaoyu Yang   +4 more
doaj   +1 more source

Catalytic enantioselective nitrone cycloadditions enabling collective syntheses of indole alkaloids

Nature Communications
Tetrahydro-β-carboline skeletons are prominent and ubiquitous in an extraordinary range of indole alkaloid natural products and pharmaceutical compounds. Powerful synthetic approaches for stereoselective synthesis of tetrahydro-β-carboline skeletons have
Xiaochen Tian, Tengfei Xuan, Jingkun Gao, Xinyu Zhang, Tao Liu, Fengbiao Luo, Ruochen Pang, Pengcheng Shao, Yun-Fang Yang, Yang Wang   +9 more
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Publisher Correction: Phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles

Nature Communications, 2019
The original PDF version of this Article contained an error in Table 3, in which all chemical structures were omitted and only the numerical data was shown. This has been corrected in the PDF version of the Article.
Lei Zhang, Shao-Hua Xiang, Jun (Joelle) Wang, Jian Xiao, Jun-Qi Wang, Bin Tan   +5 more
doaj   +1 more source

Synthesis and Application of a New Cyclic Phosphoric Acid in Enantioselective Three-Component Mannich Reactions

Molecules
A novel point-chiral six-membered cyclic phosphoric acid was synthesized starting from an enantiopure precursor via a concise three-step route. Its catalytic performance was evaluated in enantioselective three-component Mannich reactions. Under optimized
Giovanni Ghigo, Alessio Robiolio Bose, Stefano Dughera   +2 more
doaj   +1 more source