Results 181 to 190 of about 36,278 (230)
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Comparison of monomeric and polymeric chiral stationary phases
Journal of Chromatography A, 2003Two-type polymeric chiral stationary phases (pCSPs) were prepared by surface grafting of chiral acryl-type monomers on a silica gel surface modified with 3-(trimethoxysilyl)propylmethacrylate. The prepared pCSPs were characterized by IR, Fr-Raman, scanning electron microscopy, and elemental analysis.
Kwang-Pill, Lee +8 more
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Monolithic chiral stationary phases for liquid‐phase enantioseparation techniques
Journal of Separation Science, 2010AbstractThis short overview summarizes the development in the field of enantioselective monolithic chromatographic media and their application for pressure‐driven and electrokinetic separations. The major emphasis is put on the currently existing problems and the author's vision for their solution is provided.
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Derivatized vancomycin stationary phases for LC chiral separations
Talanta, 1996In this work, synthetic and natural chiral selectors were combined to form two different chiral stationary phases (CSPs). These were made by bonding R- or S-(1-naphthylethyl) carbamate (R-NEC or S-NEC)-derivatized vancomycin molecules to a silica gel support. The two CSPs were evaluated using a set of 60 enantiomeric pairs. The results were compared to
A, Berthod +3 more
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Advances in polymer materials as chiral stationary phase
Chinese Journal of Chromatography, 2016The applications of chiral drugs had a profound impact on human health. With the development of disciplines of chemistry, materials and life science, the research on the separation and analysis of chiral drugs became intensified. Chromatography and the selection of chiral stationary phase played important roles in resolving chiral drugs.
Rongji, Dai +5 more
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Imprintable brush-type chiral stationary phase
Journal of Chromatography A, 1995Abstract A chiral stationary phase (CSP) based upon a previously studied naphthamide atropisomer is described. Although CSPs based upon imprinted polymers have been known for some time, this naphthamide-derived CSP is the first reported example of an imprintable brush-type CSP.
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Cellulosic Chiral Stationary Phase Under Reversed-Phase Condition
Journal of Liquid Chromatography, 1993Abstract Chiral stationary phases on polysaccharide esters have been mainly applied under a normal phase condition. However, there are some samples that can not be analyzed under normal phase conditions because of the solubility and the procedures by which they are prepared.
A. Ishikawa, T. Shffiata
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Solution‐phase synthesis and evaluation of tetraproline chiral stationary phases
Chirality, 2012AbstractA protocol was developed for the solution‐phase synthesis of multigram amounts of two 9‐fluorenylmethoxycarbonyl (Fmoc)‐protected tetraproline peptides. These tetraproline peptides were then attached to amino derivatized silica gel. The replacement of the Fmoc group with the trimethylacetyl group lead to two tetraproline chiral stationary ...
Zhi, Dai +3 more
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HPLC Enantioseparation on Cyclodextrin-Based Chiral Stationary Phases
2012Cyclodextrin-bonded silica material is one of the most commonly used chiral stationary phases in liquid chromatography for pharmaceutical analysis and enantioseparations. The approaches for immobilization of cyclodextrins onto the silica surface influence both, the stability of the chiral stationary phase and the enantioselectivity. In this chapter, we
Yong, Wang, Siu Choon, Ng
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Chirality, 2001
AbstractA comparison of the enantiomeric resolution of (±)‐threo‐methylphenidate (MPH) (Ritalin®) was achieved on different polysaccharide based chiral stationary phases. The mobile phase used was hexane‐ethanol‐methanol‐trifluoroacetic acid (480:9.75:9.75:0.5, v/v/v/v).
Hassan Y, Aboul-Enein, Imran, Ali
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AbstractA comparison of the enantiomeric resolution of (±)‐threo‐methylphenidate (MPH) (Ritalin®) was achieved on different polysaccharide based chiral stationary phases. The mobile phase used was hexane‐ethanol‐methanol‐trifluoroacetic acid (480:9.75:9.75:0.5, v/v/v/v).
Hassan Y, Aboul-Enein, Imran, Ali
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Chiral stationary phases on a crystalline support
Mikrochimica Acta, 1996For direct HPLC resolution of enantiomers of optically active substances, supports having an optically pure organic layer with a high order of chirality are advantageous. To ensure this, the support itself has to possess a structure of well-defined regularity. For this reason, zeolite A, a material of crystalline character has been used as support, for
Lujza P. Szab� +2 more
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