Results 251 to 260 of about 328,477 (299)
Some of the next articles are maybe not open access.
Science Signaling, 2008
A transmembrane protein induced in cytokine-treated bronchial epithelial cells seems to be a long-sought primary carrier of a voltage- and calcium-dependent chloride current.
openaire +2 more sources
A transmembrane protein induced in cytokine-treated bronchial epithelial cells seems to be a long-sought primary carrier of a voltage- and calcium-dependent chloride current.
openaire +2 more sources
Amazing chloride channels: an overview
Acta Physiologica Scandinavica, 2003Abstract Aim: This review describes molecular and functional properties of the following Cl – channels: the ClC family of voltage‐dependent Cl – channels, the cAMP‐activated transmembrane conductance regulator (CFTR), Ca 2+ activated Cl – channels (CaCC) and ...
B, Nilius, G, Droogmans
openaire +2 more sources
1990
The present short overview summarizes the role of chloride channels in epithelial transport. At present, we are aware of a general concept in which chloride uptake is carrier mediated and driven by the electrochemical gradient for chloride and the cotransported or countertransported ions, and in which chloride exit occurs via chloride channels ...
R. Greger, K. Kunzelmann
openaire +1 more source
The present short overview summarizes the role of chloride channels in epithelial transport. At present, we are aware of a general concept in which chloride uptake is carrier mediated and driven by the electrochemical gradient for chloride and the cotransported or countertransported ions, and in which chloride exit occurs via chloride channels ...
R. Greger, K. Kunzelmann
openaire +1 more source
The CLC chloride channel family
Pfl�gers Archiv European Journal of Physiology, 1999Chloride channels perform important roles in the regulation of cellular excitability, in transepithelial transport, cell volume regulation, and acidification of intracellular organelles. This variety of functions requires a large number of different chloride channels that are encoded by genes belonging to several unrelated gene families. The CLC family
T J, Jentsch +3 more
openaire +2 more sources
Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984
Cl- current in GABA-sensitive neurons of the frog dorsal root ganglia was separated from other Na+, Ca2+ and K+ currents using the suction pipette technique which allows internal perfusion and current clamp. Adequacy of the internal perfusion technique was assessed from the reversal potential for GABA-induced Cl- current (EGABA) at various ...
openaire +1 more source
Cl- current in GABA-sensitive neurons of the frog dorsal root ganglia was separated from other Na+, Ca2+ and K+ currents using the suction pipette technique which allows internal perfusion and current clamp. Adequacy of the internal perfusion technique was assessed from the reversal potential for GABA-induced Cl- current (EGABA) at various ...
openaire +1 more source
CLC chloride channels and transporters
Current Opinion in Neurobiology, 2005CLC proteins are found in cells from prokaryotes to mammals and perform functions in plasma membranes and intracellular vesicles. Several genetic human diseases and mouse models underscore their broad physiological functions in mammals. These functions range from the control of excitability to transepithelial transport, endocytotic trafficking and ...
Thomas J, Jentsch +2 more
openaire +2 more sources
Chloride channels in toad skin
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1982A study of the voltage and time dependence of a transepithelial Cl- current in toad skin ( Bufo bufo ) by the voltage-clamp method leads to the conclusion that potential has a dual role for Cl- transport. One is to control the permeability of an apical membrane Cl- pathway, the other is to drive Cl- ions through ...
Larsen, Erik Hviid, Rasmussen, B E
openaire +2 more sources
1998
Abstract It has become clear that chloride channels play a role in a number of different cellular functions. Until recently the γ-amino-butyric acid (GABA) and glycine-activated - receptor anion - selective channels were the only well-characterized anion channels but, following the introduction of the patch-clamp technique, it became ...
M A Valverde, S P Hardy,, A S Monaghan
openaire +1 more source
Abstract It has become clear that chloride channels play a role in a number of different cellular functions. Until recently the γ-amino-butyric acid (GABA) and glycine-activated - receptor anion - selective channels were the only well-characterized anion channels but, following the introduction of the patch-clamp technique, it became ...
M A Valverde, S P Hardy,, A S Monaghan
openaire +1 more source
Chloride channels: a molecular perspective
Current Opinion in Neurobiology, 1996Plasma membrane Cl- channels perform a variety of functions, including control of excitability in neurons and muscle, cell volume regulation and transepithelial transport. Structurally, three classes of Cl- channels have been identified: ligand-gated, postsynaptic Cl- channels (e.g.
openaire +2 more sources
Regulation of Lymphocyte Chloride Channels
1991The chloride permeability defect which characterizes the apical membrane of secretory epithelial cells in cystic fibrosis has been difficult to study in part because of lack of accessibility of tissue for study. This problem has fostered attempts by investigators both to immortalize epithelial cell lines and to search for other cells which may serve as
P, Gardner +6 more
openaire +2 more sources